62 research outputs found

    Virtual prototyping at CERN

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    A Survey on Design Methodologies for Accelerating Deep Learning on Heterogeneous Architectures

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    In recent years, the field of Deep Learning has seen many disruptive and impactful advancements. Given the increasing complexity of deep neural networks, the need for efficient hardware accelerators has become more and more pressing to design heterogeneous HPC platforms. The design of Deep Learning accelerators requires a multidisciplinary approach, combining expertise from several areas, spanning from computer architecture to approximate computing, computational models, and machine learning algorithms. Several methodologies and tools have been proposed to design accelerators for Deep Learning, including hardware-software co-design approaches, high-level synthesis methods, specific customized compilers, and methodologies for design space exploration, modeling, and simulation. These methodologies aim to maximize the exploitable parallelism and minimize data movement to achieve high performance and energy efficiency. This survey provides a holistic review of the most influential design methodologies and EDA tools proposed in recent years to implement Deep Learning accelerators, offering the reader a wide perspective in this rapidly evolving field. In particular, this work complements the previous survey proposed by the same authors in [203], which focuses on Deep Learning hardware accelerators for heterogeneous HPC platforms

    Serum Albumin Is Inversely Associated With Portal Vein Thrombosis in Cirrhosis

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    We analyzed whether serum albumin is independently associated with portal vein thrombosis (PVT) in liver cirrhosis (LC) and if a biologic plausibility exists. This study was divided into three parts. In part 1 (retrospective analysis), 753 consecutive patients with LC with ultrasound-detected PVT were retrospectively analyzed. In part 2, 112 patients with LC and 56 matched controls were entered in the cross-sectional study. In part 3, 5 patients with cirrhosis were entered in the in vivo study and 4 healthy subjects (HSs) were entered in the in vitro study to explore if albumin may affect platelet activation by modulating oxidative stress. In the 753 patients with LC, the prevalence of PVT was 16.7%; logistic analysis showed that only age (odds ratio [OR], 1.024; P = 0.012) and serum albumin (OR, -0.422; P = 0.0001) significantly predicted patients with PVT. Analyzing the 112 patients with LC and controls, soluble clusters of differentiation (CD)40-ligand (P = 0.0238), soluble Nox2-derived peptide (sNox2-dp; P < 0.0001), and urinary excretion of isoprostanes (P = 0.0078) were higher in patients with LC. In LC, albumin was correlated with sCD4OL (Spearman's rank correlation coefficient [r(s)], -0.33; P < 0.001), sNox2-dp (r(s), -0.57; P < 0.0001), and urinary excretion of isoprostanes (r(s), -0.48; P < 0.0001) levels. The in vivo study showed a progressive decrease in platelet aggregation, sNox2-dp, and urinary 8-iso prostaglandin F2 alpha-III formation 2 hours and 3 days after albumin infusion. Finally, platelet aggregation, sNox2-dp, and isoprostane formation significantly decreased in platelets from HSs incubated with scalar concentrations of albumin. Conclusion: Low serum albumin in LC is associated with PVT, suggesting that albumin could be a modulator of the hemostatic system through interference with mechanisms regulating platelet activation

    I Prototipi Virtuali del CERN

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    DataGrid

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    DataGrid is a project funded by the European Union that aims to enable access to geographically distributed computing power and storage facilities belonging to different institutions. This will provide scientists with an unprecedented computing and data management tool. DataGrid is led by CERN, together with 20 other scientific and industrial partners

    A Web browser for LHC design integration

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    CMS Detector Assembly (17 minutes)

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    This 17-minute long animation shows the construction of the main structural components of CMS in the surface hall in Cessy and offers a detailed overview of the installation in the experimental cavern. Produced by: CERN Multimedia Production Unit Director: Silvano de Gennaro 17:00 min. / 01 June 200

    Virtual reality

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    Informaticiens Sans Frontieres: Helping to bridge the Digital Divide

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    ISF was formed as a CERN club during the World Summit for the Information Society, in Geneva, in 2003. Today we are involved in a number of international projects aimed to helping Africa bridge the Digital Divide, as well as using computing power (BOINCs) in the research against Malaria, or creating GRIDs that could allow African universities to join us in scientific research projects such as the LHC. Our latest project, named MANGO Net, is aimed at capacity building, by creating a network of computer assembly schools across the continent, which would form hardware and software technicians, create assembly centres, and lay the foundation for a future IT industry. ISF est né comme un club du CERN, en 2003, pendant le Sommet Mondiale de la Société de l'information à Genève. Aujourd'hui nous participons à plusieurs projets avec le but d'aider l'Afrique à reduire la Fracture Numérique, ou de fournir de la puissance de calcul (BOINC) à la recherche contre le Paludisme, ou en créant des GRIDs qui pourraient permettre aux universités africaines de se joindre à nous dans des projets de recherche comme le LHC. Notre dernier projet, appelé MANGO Net, a comme but la création d'un reseau d'écoles d'assemblage d'ordinateurs à travers le continent, qui vont former des téchniciens compétents, créer des centres d'assemblage, et ainsi jeter les fondations pour le développement d'une industrie Informatique à venir. La presentation sera en Anglais, mais avec interventions en Françai
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