114 research outputs found
Positive tension 3-branes in an bulk
In this work, we review and extend the so-called consistency conditions for
the existence of a braneworld scenario in arbitrary dimensions in the
Brans-Dicke (BD) gravitational theory. After that, we consider the particular
case of a five-dimensional scenario which seems to have phenomenological
interesting implications. We show that, in the BD framework, it is possible to
achieve necessary conditions pointing to the possibility of accommodating
branes with positive tensions in an AdS bulk by the presence of the additional
BD scalar field, avoiding in this way the necessity of including unstable
objects in the compactification scheme. Furthermore, in the context of time
variable brane tension, it is shown that the brane tension may change its sign,
following the bulk cosmological constant sign.Comment: 15 pages, new version to appear in JHE
The Role of Sarcopenic Obesity in Cancer and Cardiovascular Disease: A Synthesis of the Evidence on Pathophysiological Aspects and Clinical Implications
Obesity is globally a serious public health concern and is associated with a high risk of cardiovascular disease (CVD) and various types of cancers. It is important to evaluate various types of obesity, such as visceral and sarcopenic obesity. The evidence on the associated risk of CVD, cancer and sarcopenic obesity, including pathophysiological aspects, occurrence, clinical implications and survival, needs further investigation. Sarcopenic obesity is a relatively new term. It is a clinical condition that primarily affects older adults. There are several endocrine-hormonal, metabolic and lifestyle aspects involved in the occurrence of sarcopenic obesity that affect pathophysiological aspects that, in turn, contribute to CVD and neoplasms. However, there is no available evidence on the role of sarcopenic obesity in the occurrence of CVD and cancer and its pathophysiological interplay. Therefore, this review aims to describe the pathophysiological aspects and the clinical and epidemiological evidence on the role of sarcopenic obesity related to the occurrence and mortality risk of various types of cancer and cardiovascular disease. This literature review highlights the need for further research on sarcopenic obesity to demonstrate the interrelation of these various associations
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