Effects of Tropical Legume (\u3cem\u3eStylosanthes cv.\u3c/em\u3e Campo Grande) Silage and Dietary Protein Levels on Animal Performance of Finishing Beef Cattle

Recently, the interest in legume silage for livestock systems has increased in tropical countries (Heinritz et al., 2012) because of the high inclusion of the protein sources in the concentrate used in feedlot diets, like soybean meal. Stylosanthes cv. Campo Grande was developed in Brazil and this cultivar has a good adaptation to tropical conditions, as soils with low fertility and high acidity (Fernandes et al., 2005). Recently, this legume has been indicated for silage making because of its nutritional value and previous results with beef cattle have showed similar performance and digestibility in comparison with corn silage (Souza et al., 2014). The objective of this study was to evaluate the effects of Stylosanthes cv. Campo Grande silage (StS) and corn silage (CS) with two dietary protein levels

Same-Sign Taus Signatures of Maximally Flavor-Violating Scalars at the LHC

We explore single and double flavor-violating scalars (flavons) production at the 13 and 14 TeV LHC in an effective field theory formulation where flavons always change the flavor of Standard Model fermions. When those scalars couple to mass, their flavor-changing couplings to top quarks and tau leptons are favored. Focusing on the mass region below the top quark mass, we find couplings that fit the muon and electron $(g-2)$ discrepancies and avoid several current experimental constraints. We determine the potential of the LHC to exclude or discover such a new physics scenario with clean signatures consisting of same-sign tau leptons and the simultaneous observation of resonances in the tau plus electron or muon invariant mass. We found that in the double production mode, effective couplings down to order $10^{-2}$ TeV$^{-1}$ can be probed for flavon masses in the 10-170 GeV range at the HL-LHC at 14 TeV, but couplings down to 0.1 TeV$^{-1}$ can be excluded at 95\% confidence level with data collected by the 13 TeV LHC in the same mass interval.Comment: 32 pages, 12 figures, 2 table

Identification of "pathologs" (disease-related genes) from the RIKEN mouse cDNA dataset using human curation plus FACTS, a new biological information extraction system

BACKGROUND: A major goal in the post-genomic era is to identify and characterise disease susceptibility genes and to apply this knowledge to disease prevention and treatment. Rodents and humans have remarkably similar genomes and share closely related biochemical, physiological and pathological pathways. In this work we utilised the latest information on the mouse transcriptome as revealed by the RIKEN FANTOM2 project to identify novel human disease-related candidate genes. We define a new term "patholog" to mean a homolog of a human disease-related gene encoding a product (transcript, anti-sense or protein) potentially relevant to disease. Rather than just focus on Mendelian inheritance, we applied the analysis to all potential pathologs regardless of their inheritance pattern. RESULTS: Bioinformatic analysis and human curation of 60,770 RIKEN full-length mouse cDNA clones produced 2,578 sequences that showed similarity (70–85% identity) to known human-disease genes. Using a newly developed biological information extraction and annotation tool (FACTS) in parallel with human expert analysis of 17,051 MEDLINE scientific abstracts we identified 182 novel potential pathologs. Of these, 36 were identified by computational tools only, 49 by human expert analysis only and 97 by both methods. These pathologs were related to neoplastic (53%), hereditary (24%), immunological (5%), cardio-vascular (4%), or other (14%), disorders. CONCLUSIONS: Large scale genome projects continue to produce a vast amount of data with potential application to the study of human disease. For this potential to be realised we need intelligent strategies for data categorisation and the ability to link sequence data with relevant literature. This paper demonstrates the power of combining human expert annotation with FACTS, a newly developed bioinformatics tool, to identify novel pathologs from within large-scale mouse transcript datasets

Hoja Geológica 4369-30 Bajo Chiquichan, Provincia del Chubut.

Fil: Silva Nieto, Diego G. Servicio Geológico Minero Argentino (SEGEMAR); Argentina.Fil: Lizuain, Antonio. Servicio Geológico Minero Argentino (SEGEMAR); Argentina.Fil: Páez, Manuel. Comisión Nacional de Energía Atómica; ArgentinaLa Hoja 4369-30, Bajo de Chiquichan, se encuentra ubicada en el centro-norte de la provincia del Chubut, en el ámbito geológico de Patagonia extraandina, al sur del Macizo Nordpatagónico y al norte del río Chubut. Sus rasgos orográficos más representativos son el bajo Chiquichan por el este, el cerro Gobernador por el oeste y los cerros Ponte y Bororó por el norte y sur respectivamente. El arroyo Perdido, de carácter efímero, atraviesa la Hoja por el sector noroccidental. Dentro del ámbito de la Hoja no hay núcleos poblacionales, los centros urbanos más importantes son el pueblo de Las Plumas ubicado 80 km al sur, sobre la ruta nacional 25, y la aldea Mirasol que se halla a unos 20 km del límite norte. En cuanto a la estratigrafía las rocas más antiguas reconocidas son ignimbritas y andesitas de la Formación Marifil, asignadas al Jurásico inferior, las que son sobrepuestas en discordancia por sedimentitas continentales fluviales con mucho aporte piroclástico, de la Formación Cerro Barcino del Grupo Chubut, de edad Cretácico inferior. Sobre estas últimas se disponen limolitas, arcilitas y piroclastitas de la Formación Puesto Manuel Arce y areniscas conglomeradicas de la Formación Puntudo Chico, ambas de ambiente continental y de edad cretácica tardía. Dentro del Paleógeno se han distinguido varias unidades: la Formación Salamanca, integrada principalmente por areniscas, arcilitas y limolitas de ambiente marino litoral y de edad paleocena; la Formación El Buitre, representada por basanitas y basaltos alcalinos de edad eocena que intruyen discordantemente a las sedimentitas de la Formación Salamanca que las sobreyacen, y la Formación Chiquichan, compuesta esencialmente por basaltos y piroclastitas asignados tentativamente al Oligoceno. El Cuaternario está representado por cuatro niveles de pedimentación cubiertos por depósitos aluviales, asignados los más antiguos al Pleistoceno y al Holoceno los más modernos. Finalmente, se han reconocido depósitos de remoción en masa, aluviales, salinos, coluviales y eólicos de edad holocena. Dentro de la Hoja no hay registros de actividad minera, tanto metalífera como no metalífera, sin embargo, se han reconocido numerosas anomalías de uranio en las sedimentitas cretácicas y paleógenas de las formaciones Puesto Manuel Arce y Salamanca, respectivamente, que han sido motivo de estudio por parte de la Comisión Nacional de Energía Atómica. En el ámbito de la Hoja se destacan como Sitios de Interés Geológico, el Barrio Chino, coloridas geoformas de erosión; La Rinconada, una profunda quebrada en la que se exponen todas las unidades sedimentarias cretácicas y paleógenas; el cerrito Wincheun, pequeño chihuído o chimenea volcánica que intruye a sedimentitas de la Formación Cerro Barcino y el anticlinal del Bajo de Chiquichan

O que é mais eficiente para perda de peso: exercício contínuo ou intermitente? com ou sem dieta? uma revisão baseada em evidências

Modelo do estudo: Revisão sistemática de literatura Objetivo: Apresentar evidências científicas acerca do tipo de exercício aeróbio (Contínuo vs. Intermitente) que resulta em melhores efeitos na redução do peso corporal. Metodologia: Foi realizada revisão da literatura nas bases de dados Pubmed, Medline, ISI Web of Knowledge, Ebsco Host e Scopus de artigos a partir do ano 2000. Resultados: A combinação do exercício aeróbio e restrição calórica podem maximizar a perda de peso em indivíduos com sobrepeso. Ao comparar os dois tipos de exercícios aeróbios, a maior parte das evidências sugerem superioridade do intermitente em comparação ao contínuo na perda de peso. Conclusão: Intervenções realizadas com dieta restrita combinadas com programas de exercícios realizados de três a seis vezes semanais, de preferência intermitente, em intensidade moderada a alta, apresentaram resultados mais significativos para perda de peso em comparação ao exercício contínuo.Study design: Systematic literature review Objective: To present scientific evidence about the type of aerobic exercise (Continuous vs. Intermittent) that results in better effects on reducing body weight. Methodology: Literature review was performed on Pubmed, Medline, ISI Web of Knowledge, Ebsco Host and Scopus of articles from the year 2000. Results: The combination of aerobic exercise and caloric restriction can maximize weight loss in overweight individuals. By comparing the two types of aerobic exercises, most evidence suggests superiority of intermittent exercise compared to continuous exercise in weight loss. Conclusion: Interventions performed with restricted diet combined with exercise programs performed from three to six times weekly, preferably intermittent, from moderate to high intensity, showed more significant results for weight loss compared to continuous exercise

Morphogenic Responses of Two \u3cem\u3eBrachiaria\u3c/em\u3e Genotypes in Response to Clipping Frequency

Tropical grasslands represent an important resource for the Brazilian cattle industry, which is heavily dependent on grazed pastures. Total pasture area in the country totals 196 M ha (23% of the country’s land area) (FAO 2013). The genus Brachiaria represents around 85% of cultivated pastures in Brazil (Moreira et al. 2009), 40% of which are established with B. brizantha cv. Marandu (Barbosa 2006). Mulato II is a new hybrid brachiaria grass cultivar which has been developed to improve agronomic characteristics, broaden the range of adaptation, and to ensure high forage production and nutritive value. It has also been viewed as a means of reducing the dependence on the Marandu palisade grass monoculture (Argel et al. 2007). The use of new cultivars should be based on adequate understanding of physiological processes and growth potential under a range of management practices. Morphogenic characteristics allow for accessing herbage accumulation potential through the measurement of tissue synthesis and senescence in forage plants. Management practices such as defoliation frequency can modify assimilate partitioning in the forage plant, affecting morphogenic characteristics related to growth rate and forage nutritive value. The objective of this research was to describe and explain morphogenic differences between Marandu palisade grass and Mulato II brachiaria grass as affected by harvest frequency

Embedded System for Real Color Composition in Experimental Physics

Software can be considered educational when properly contextualized in a relationship of teaching and learning. This paper describes an embedded system and an educational software developed and applied in experimental physics to real and virtual colors composition. The educational system developed allows student interaction by voice commands, which makes the assimilation process of red/green/blue (RGB) color formation concepts more didactic and playful. The application of educational software in experiments also allows to verify, in real time, the influence of programs change on the physical phenomena and stimulates the logical reasoning development and consequently the autonomy of the students, to the measure that can raise hypothesis, make modifications in the programming and take off conclusions from the practical results obtained