52 research outputs found
EFFECT OF CORTISOL TREATMENT ON HORMONAL RELATIONSHIPS IN CONGENITAL ADRENAL HYPERPLASIA
The temporal relationship between administration of cortisol and serum 17Α-hydroxyprogesterone was investigated in five patients aged 9-19 years with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. There was marked variability in the 17Α-hydroxyprogesterone response (determined hourly for 24 h) of individual patients to administration of cortisol. Mean concentration was less than 0.030 Μmol/l in one patient but 0.519Μ mol/l in another. Levels were higher in all patients while off treatment, and were greatest in those with salt-losing adrenal hyperplasia. Growth hormone secretion was not suppressed by treatment with cortisol. Withdrawal of cortisol for 3 days resulted in a significant decrease in the mean serum FSH/LH ratio and a rise in serum testosterone in all subjects. Episodic release of gonadotrophins persisted in the adolescent patients.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75713/1/j.1365-2265.1977.tb02002.x.pd
Phasenhater Verlauf der 17-Hydroxycorticoidausscheidung beim Meerschweinchen nach eint�giger Behandlung mit ACTH
OESTROGEN DYNAMICS IN ADRENAL VENOUS EFFLUENTS IN CONGENITAL VIRILIZING ADRENAL HYPERPLASIA
Use of the Hypospray Jet Injector for the Intra-Articular and Local Administration of Hydrocortisone Acetate
EVALUATION OF RESECTION OF PITUITARY MICROADENOMA FOR THE TREATMENT OF CUSHING'S DISEASE IN PATIENTS WITH RADIOLOGICALLY NORMAL SELLA TURCICA
The effect of corticotrophin zinc on plasma 17-hydroxycorticoids as a test of adrenal cortical function
- …