UCx_x target design for the SPIRAL 2 project and the ALTO project

ACC NESTERInternational audienceTwo ways of production of radioactive beams using uranium carbide targets are taken into consideration: fission induced by fast neutrons and by bremsstrahlung radiation. For the SPIRAL 2 project, the fission of 238U in uranium carbide target will be induced by a neutron flow created by bombarding a carbon converter with a 40 MeV high intensity deuteron beam. Calculations and design of the target in order to reach 1013 fissions/s with good release time have been done. The second way is the photofission using an electron beam. In 2005 the ALTO project (Accélérateur Linéaire Auprès du Tandem d'Orsay) will give a 50 MeV/10$\mu$A electron beam. This facility will allow more than 1011 fissions/s. In this case, the electron beam hits the target without converter. Calculations realised in order to estimate the production are used to choose the best target shape. For the two cases some R & D on targets to improve release is described

Clinical and Genetic Study of Algerian Patients with Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is the second most common lethal autosomal recessive disorder. It is divided into the acute Werdnig-Hoffmann disease (type I), the intermediate form (type II), the Kugelberg-Welander disease (type III), and the adult form (type IV). The gene involved in all four forms of SMA, the so-called survival motor neuron (SMN) gene, is duplicated, with a telomeric (tel SMN or SMN1) and a centromeric copy (cent SMN or SMN2). SMN1 is homozygously deleted in over 95% of SMA patients. Another candidate gene in SMA is the neuronal apoptosis inhibitory protein (NAIP) gene; it shows homozygous deletions in 45–67% of type I and 20–42% of type II/type III patients. Here we studied the SMN and NAIP genes in 92 Algerian SMA patients (20 type I, 16 type II, 53 type III, and 3 type IV) from 57 unrelated families, using a semiquantitative PCR approach. Homozygous deletions of SMN1 exons 7 and/or 8 were found in 75% of the families. Deletions of exon 4 and/or 5 of the NAIP gene were found in around 25%. Conversely, the quantitative analysis of SMN2 copies showed a significant correlation between SMN2 copy number and the type of SMA

Study of temperature variation effect on the thermoelectric properties of a thermoelectric generator with BiCuseO molecules

Thermoelectric-power generation poses challenges, which are of fundamental and technological nature. Increasing thermoelectric efficiency for work, the therme of the associated policy, has encountered problems related, for example, to heat recovery and conversion to electricity. It is widely recognized that the augmentation of efficient electromechanical systems as a strategic subject of applied study in light of problems related, for example, to waste heat recuperation and conversion to electricity. This results in an abundant literature on the subject. Recent advances in the technological development of TEGs are based on advances in materials science: new materials and new techniques for the production of specific structures have made it possible to improve device performance through the characterization and optimization of their thermal and electrical transport properties. This paper presents a simulation study on the effect of temperature variation on a thermoelectric generator at the base of BiCuSeO, using the mathematical method of the finite element model