7 research outputs found
Women’s attitude towards umbilical cord blood banking in Poland
Introduction:
Umbilical cord blood (UCB) is considered as a valuable potential source of hematopoietic stem and progenitor cells. A process of collecting and storing UCB in the immediate period after the birth is called UCB banking
Difficulties in the management of hypokalemia in a pregnant patient with Gitelman syndrome
Gitelman syndrome (GS) is a rare renal disorder, and little is known about its impact on pregnancy. We report the successful outcome of pregnancy in a patient with GS that was managed with aggressive oral and intravenous potassium supplementation
Adverse outcome of T3-predominant maternal Grave’s disease during pregnancy in the mother and the offspring
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The impact of COVID-19 pandemic on reproductive intentions among the Polish population
Objectives: The study was conducted in order to determine the impact of the COVID-19 pandemic on the fertility intentions among the Polish population.
Material and methods: A cross-sectional, questionnaire-based online study was carried out among Polish adults in order to determine the impact of the COVID-19 pandemic on the reproductive plans of the Polish society. A total of 984 participants correctly completed the survey.
Results: The pandemic has affected the reproductive intentions of 22% (n = 216) of the respondents, most of them want to have a child later than they previously planned (74.1%). The relationship between the change in reproductive intentions and the concerns about the pandemic was found. Most of those who changed their plans were afraid that the access to prenatal care and delivery services could be limited (86.6%) or were afraid about giving birth at the hospital (81%). More than half (51.9%) of those who changed reproductive plans were afraid of losing their income and 40.3% had already experienced a decrease in their income. The change in partner’s emotional relationships was also observed. More than half of respondents (56.7%) admitted that during the pandemic they had developed a deeper emotional relationship with their partners or felt more emotionally supported (56.6%). Most participants responded that the frequency of their sexual intercourses was not affected (66.7%) and that they had not experienced limited access to contraceptives (95.1%) during the pandemic.
Conclusions: The COVID-19 pandemic has affected Polish people’s reproductive intentions. Concerns related to healthcare access and the economic difficulties have the most significant impact
Infantile hemangioma
Infantile hemangiomas are the most common vascular tumors of infancy. They usually appear within the first few weeks after birth and undergo regression over time, usually by the age of four. They are more common in girls, Caucasians, twins, infants born preterm or with a low birth weight. The pathogenesis of hemangiomas remains not fully understood. Infantile hemangiomas can be classified based on their depth and anatomical configuration. Superficial hemangiomas appear as a red macule or patch, while deep hemangiomas appear as a bluish papule or nodule. In most cases the diagnosis is based on the clinical picture. The differential diagnosis includes vascular anomalies, pyogenic granuloma or Kaposiform hemangioendothelioma. In most cases, infantile hemangiomas do not require any treatment. Only 10–20% of cases need to be treated because of complications. Propranolol administered orally is the treatment of choice
Pregnant Women’s Knowledge of and Attitudes towards Influenza Vaccination during the COVID-19 Pandemic in Poland
Pregnant women are more susceptible to influenza virus infections due to the immunological and physiological changes in the course of pregnancy. Vaccination during pregnancy is a safe and effective method for protecting both the mothers and the infants from influenza and its complications. This study was conducted in order to determine the knowledge and attitudes of Polish pregnant women towards influenza vaccination during the COVID-19 pandemic. A questionnaire-based and self-administered study was carried out fully online and a total of 515 women participated. A total of 52% (n = 268) of surveyed women answered that vaccination against influenza during pregnancy was safe. However, only 21% (n = 108) were vaccinated against influenza during their current pregnancy and 17.5% (n = 90) intended to be vaccinated. The participants indicated many concerns about getting vaccinated during pregnancy, but also many benefits that come with the vaccination. General knowledge about influenza, its complications, and vaccination was quite high in the study group
<i>N</i>′-Substituted 4-Phenylpicolinohydrazonamides with Thiosemicarbazone Moiety as New Potential Antitubercular Agents: Synthesis, Structure and Evaluation of Antimicrobial Activity
Three new 4-phenylpicolin derivatives with a thiosemicarbazone structure were synthesized and evaluated for tuberculostatic activity. The compounds were obtained by the condensation of methyl 4-phenylpicolonimidate with the corresponding cycloalkylamino-1-carbothiohydrazides. The 1H NMR temperature spectra obtained showed proton lability at the nitrogen atom N2, and X-ray crystallography confirmed the zwitterionic structure of all products. ADME calculations indicate that the compounds can be tested as future drugs. All compounds were absorbed in the gastrointestinal tract. All compounds also showed very good tuberculostatic activity (MIC 3.1–12.5 µg/mL). Derivative 1b showed the best selectivity for M. tuberculosis compared to the other pathogenic species tested. The study has allowed the emergence of imine derivative 1b as a good structure for further optimization in the search for antitubercular drugs