Machine Learning Approach for Smile Detection in Real Time Images

Recognizing facial expressions of human beings by a computer is an interesting and challenging problem. A system that performs the operation of face detection and facial feature extraction accurately and in real time would form a big step in achieving a humanlike interaction between man and machine. In this paper, we propose a method for detecting Smile in real time Images by machine learning approach. Machine learning method involves training a classifier and using it in real time images to determine smile. Our implemented approach has been tested on several Images from different databases and the achieved results were found to be very satisfactory

Randomised trial of mefenamic acid versus tranexamic acid in management of menorrhagia

Background: The objective of the study was to compare the efficacy of mefenamic acid, a non-inflammatory drug with tranexamic acid, an antifibrinolytic drug in management of menorrhaghia.Methods: Randomised trial of women attending outpatient department of St. Philomena’s hospital, Bangalore with complaints of menorrhagia. Fifty four patients with complaints of menorrhagia were randomly assigned to receive either mefenamic acid 500 mg tid (group A- 24 patients) or tranexamic acid 1 gm TID (group B- 26 patients) from day one to day five for three consecutive menstrual cycles.Results: Reduction in menstrual blood loss as assessed by pictoral blood loss assessment chart was more in group B (50%) than in Group A (30%) (ANOVA, covariates with F=59.647, p0.05).Conclusions: Both mefenamic acid and tranexamic acid were effective in management of menorrhagia. Tranexamic acid was significantly superior to mefenamic acid in terms of reduction in menstrual blood loss

Role of sex hormone binding globulin as the early predictor for gestational diabetes mellitus

Background:  The aim of this study was to find role of SHBG as an early predictor for gestational diabetes mellitus.Methods: A hospital based prospective/observational/diagnostic and explorative study. The necessary information was collected from the participants through the prepared set of questionnaires. Pregnant women between 11 to 14 weeks of gestation who visited JSS OPD for antenatal checkup satisfying inclusion and exclusion criteria giving informed and written consent for the study were examined clinically. 3ml of venous blood was drawn with aseptic precautions for the estimation of SHBG and adiponectin. OGTT with 75gms glucose first done at 11 to 14weeks and again at 24-28 weeks and 32-36 weeks were done to the same patient to find out whether the patient developed GDM or not. These mothers were followed periodically till delivery. The sensitivity and specificity of SHBG were assessed and compared in patients who developed GDM.Results: 100 cases were selected for the study. About 12 patients were diagnosed as gestational diabetes mellitus in present study by OGCT at 32 weeks to 36 weeks. In present study about 14 patients had low level of SHBG. Low level of SHBG is found to be statistically significant in predicting GDM in first trimester.Conclusions: The combination of SHBG can be used as predictor of GDM in first trimester

Insulin resistance in obese and lean women with polycystic ovarian syndrome

Background: According to NIH criteria for PCOS, the estimated prevalence of this disorder has been reported to range from 4% to 10% of women in their reproductive years, which designates PCOS as the most common endocrinopathy of women. Insulin resistance is common in PCOS and obesity contributes an additional component to insulin resistance in obese PCOS.Methods: The study was a prospective study. One-hundred and twenty PCOS women were divided into two groups: Group O - obese (n = 60) and Group L - lean (body mass index [BMI] cutoff <23 kg/m2). Oral glucose tolerance test, serum fasting insulin and HOMA- IR were compared between these groups.Results: Impaired glucose tolerance was seen in 33.3 % of lean PCOS and 36.7% of obese PCOS women. 5% of lean PCOS and 10% of obese PCOS women had hyperinsulinemia. 38.3% of lean PCOS and 51.7% of obese PCOS women had insulin resistance. But the differences were not statistically significant. However, HOMA-IR and fasting insulin values showed a significant positive correlation with BMI.Conclusions: Both obese and lean women with PCOS are vulnerable to the problems of insulin resistance irrespective of BMI and insulin resistance shows a positive correlation with BMI

Reproductive outcome of a patient with congenital adrenal hyperplasia: case report

Congenital Adrenal Hyperplasia are a group of inherited autosomal recessive enzymatic defects of adrenal steroid biosynthesis. Low pregnancy rate has been reported in women with CAH. Several factors have been suggested to contribute to this subfertility such as androgen excess, adrenal progesterone hyper secretion, consequences of genital reconstructive surgery, secondary PCOS and psychosexual factors. In contrast to this subfertility, pregnancies are normal and uneventful. During pregnancy, maternal & fetal problems are confined to these deficiencies. Adequate glucocorticoid therapy and improvement of surgical and psychological management could contribute to optimize fertility in CAH. The interposition of the placenta on the HPA axis & other endocrine changes during pregnancy impact considerably on the clinical evaluation of CAH. A 21 years old Primigravida presented to us at 13 weeks of gestation with history of CAH on treatment and vaginoplasty done in the childhood. Endocrinologist opinion was taken, and steroids continued. Advised to meet genetist and follow up for prenatal testing. But patient denied. Antenatal period was uneventful. Patient underwent Emergency LSCS in view of CPD in labour at 36+6 weeks of gestation. Pre-op stress dose of steroid given. A girl baby of birth weight 2.13 kg was born with good Apgar scores. Perioperative period uneventful. Preconception health, including hormonal, psychosexual and anatomical barriers to fertility should be addressed early in women with CAH. This review provides fertility outcome and pregnancy issues of a woman with CAH

Ru (III) Catalyzed Oxidation of Aliphatic Ketones by N-Bromosuccinimide in Aqueous Acetic Acid: A Kinetic Study

Kinetics of Ru (III) catalyzed oxidation of aliphatic ketones such as acetone, ethyl methyl ketone, diethyl ketone, iso-butylmethyl ketone by N-bromosuccinimide in the presence of Hg(II) acetate have been studied in aqueous acid medium. The order of [N-bromosuccinimide] was found to be zero both in catalyzed as well as uncatalyzed reactions. However, the order of [ketone] changed from unity to a fractional one in the presence of Ru (III). On the basis of kinetic features, the probable mechanisms are discussed and individual rate parameters evaluated

A novel multiplex PCR system for the detection of virulence associated genes of E. coli O157:H7 from food system

In view of the importance E. coli serotype 0157:H7 in human diseases, an easy and quick system is desirable to detect toxin producing strains. In this report, we describe standardization of a novel multiplex Polymerase Chain Reaction (mPCR) assay for simultaneous detection of four important genes associated with the organism E. coli 0157:H7 viz., stx 1, stx 2, eae A, hly A along with an internal amplification control (IAC). The mPCR method developed in the present study is sensitive enough to detect cells as low as 103 CFU ml-1 or g-1 of the food samples. The E. coli 0157:H7 strains having been identified to contain the gene in the mPCR were unequivocally detected positive for the serological and conventional culture method.&nbsp; As E. coli 0157:H7 is qualified as biowarfare agent; this mPCR system is of immense help in detecting them during emergencies of biological war and suspected outbreaks.&nbsp

Bark anatomy of four species of Cinnamomum (Lauraceae) from Kerala

Bark anatomy of four species of&nbsp;Cinnamomum&nbsp;- three cultivated (C. verum, C. cassia, C. camphora) and the most common wild cinnamon (C. malabatrum) arereporLed here. They differ with regard to many characters such as the nature of the scierenchymatous groups in the pericyciic region, nature of the phloem rays, distl;bution of phloem fibres and in the presence of crystalline inclusions. The differences in the bark structure are useful in distinguishing the genuineness of the true cinnamon (C. verum) bark and also in the taxonomy of the genus. &nbsp