In situ stress measurements at the Spent Fuel Test-Climax facility

The status of the following studies is given: in situ state of stress; stress gradient into rib from south heater drift; pillar stresses; and rock deformational properties. 11 references, 38 figures, 12 tables

May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

Aims Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening worldwide. The 2018 campaign was expanded, aiming to include more participants and countries. Methods and results Eighty-nine countries participated in MMM 2018. Volunteers (≥18 years) were recruited through opportunistic sampling at a variety of screening sites. Each participant had three BP measurements and completed a questionnaire on demographic, lifestyle, and environmental factors. Hypertension was defined as a systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or taking antihypertensive medication. In total, 74.9% of screenees provided three BP readings. Multiple imputation using chained equations was used to impute missing readings. 1 504 963 individuals (mean age 45.3 years; 52.4% female) were screened. After multiple imputation, 502 079 (33.4%) individuals had hypertension, of whom 59.5% were aware of their diagnosis and 55.3% were taking antihypertensive medication. Of those on medication, 60.0% were controlled and of all hypertensives, 33.2% were controlled. We detected 224 285 individuals with untreated hypertension and 111 214 individuals with inadequately treated (systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg) hypertension. Conclusion May Measurement Month expanded significantly compared with 2017, including more participants in more countries. The campaign identified over 335 000 adults with untreated or inadequately treated hypertension. In the absence of systematic screening programmes, MMM was effective at raising awareness at least among these individuals at risk

Carbonyl Reductase 3 (CBR3) Mediates 9-cis-Retinoic Acid-Induced Cytostatis and is a Potential Prognostic Marker for Oral Malignancy

The molecular mechanisms of growth suppression by retinoic acid (RA) were examined. Our results suggest that the cytostatic effects of RA could be mediated by the activation of endogenous CBR3 gene in oral squamous cell carcinomas (OSCCs), and the expression is a potential marker for oral malignancy

The CARMA-NRO Orion Survey—data release

With this research note, we are releasing the CARMA-NRO Orion Survey data first presented in Kong et al., enhanced with additional coverage of the L1641-C region to the south of the integral-shaped filament. We are including position–position–velocity cubes for the molecular lines 12CO(1–0), 13CO(1–0), and C18O(1–0). The original paper includes details of the data reduction and final sensitivity. The mapped region now spans about 2.º5 along the Orion A cloud in the north–south direction, providing an unprecedented overview of the extended molecular gas. The associated data cubes are publicly available on the Harvard Dataverse 10.7910/DVN/6Q26PN (Version 3). Kong et al. and this research note should be cited when using these data

The CARMA-NRO Orion Survey

We present the first results from a new, high-resolution (CO)-C-12(1-0), (CO)-C-13(1-0), and (CO)-O-18(1-0) molecular-line survey of the Orion A cloud, hereafter referred to as the CARMA-NRO Orion Survey. CARMA observations have been combined with single-dish data from the Nobeyama 45 m telescope to provide extended images at about 0.01 pc resolution, with a dynamic range of approximately 1200 in spatial scale. Here we describe the practical details of the data combination in uv space, including flux scale matching, the conversion of single-dish data to visibilities, and joint deconvolution of single-dish and interferometric data. A Delta-variance analysis indicates that no artifacts are caused by combining data from the two instruments. Initial analysis of the data cubes, including moment maps, average spectra, channel maps, position-velocity diagrams, excitation temperature, column density, and line ratio maps, provides evidence of complex and interesting structures such as filaments, bipolar outflows, shells, bubbles, and photo-eroded pillars. The implications for star formation processes are profound, and follow-up scientific studies by the CARMA-NRO Orion team are now underway

The CARMA-NRO Orion Survey—data release

With this research note, we are releasing the CARMA-NRO Orion Survey data first presented in Kong et al., enhanced with additional coverage of the L1641-C region to the south of the integral-shaped filament. We are including position–position–velocity cubes for the molecular lines 12CO(1–0), 13CO(1–0), and C18O(1–0). The original paper includes details of the data reduction and final sensitivity. The mapped region now spans about 2.º5 along the Orion A cloud in the north–south direction, providing an unprecedented overview of the extended molecular gas. The associated data cubes are publicly available on the Harvard Dataverse 10.7910/DVN/6Q26PN (Version 3). Kong et al. and this research note should be cited when using these data