Correlation Functions of (2k-1, 2) Minimal Matter Coupled to 2D Quantum Gravity

We compute N-point correlation functions of non-unitary (2k-1, 2) minimal matter coupled to 2D quantum gravity on a sphere using the continuum Liouville field approach. A gravitational dressing of the matter primary field with the minimum conformal weight is used as the cosmological operator. Our results are in agreement with the correlation functions of the one-matrix model at the k-th critical point.Comment: 9 pages, STUPP-92-13

The Critical Ising Model on a M\"obius Strip

We study the two-dimensional critical Ising model on a M\"obius strip based on a duality relation between conformally invariant boundary conditions. By using a Majorana fermion field theory, we obtain explicit representations of crosscap states corresponding to the boundary states. We also discuss the duality structure of the partition functions.Comment: 6 pages, ptptex, to appear in Prog. Theor. Phy

Logarithmic Behaviours in the Feigin-Fuchs Construction of the c=-2 Conformal Field Theory

We obtain logarithmic behaviours of a four-point correlation function in the c=-2 conformal field theory by using the Feigin-Fuchs construction. It becomes an indeterminate form by a naive evaluation, but is obtained by introducing an appropriate regularization procedure.Comment: LaTeX, 7 page

Minimal String Theory is Logarithmic

We study the simplest examples of minimal string theory whose worldsheet description is the unitary (p,q) minimal model coupled to two-dimensional gravity (Liouville field theory). In the Liouville sector, we show that four-point correlation functions of `tachyons' exhibit logarithmic singularities, and that the theory turns out to be logarithmic. The relation with Zamolodchikov's logarithmic degenerate fields is also discussed. Our result holds for generic values of (p,q).Comment: Latex2e 13 pages; v.2: minor corrections, typos fixe

Logarithmic Correlation Functions in Liouville Field Theory

We study four-point correlation functions with logarithmic behaviour in Liouville field theory on a sphere, which consist of one kind of the local operators. We study them as non-integrated correlation functions of the gravitational sector of two-dimensional quantum gravity coupled to an ordinary conformal field theory in the conformal gauge. We also examine, in the (p,q) minimal conformal field theories, a condition of the appearance of logarithmic correlation functions of gravitationally dressed operators.Comment: 8 pages, LaTeX, to appear in Phys. Lett.

SXDF-ALMA 2 Arcmin^2 Deep Survey: Resolving and Characterizing the Infrared Extragalactic Background Light Down to 0.5 mJy

We present a multi-wavelength analysis of five submillimeter sources (S_1.1mm = 0.54-2.02 mJy) that were detected during our 1.1-mm-deep continuum survey in the SXDF-UDS-CANDELS field (2 arcmin^2, 1sigma = 0.055 mJy beam^-1) using the Atacama Large Millimeter/submillimeter Array (ALMA). The two brightest sources correspond to a known single-dish (AzTEC) selected bright submillimeter galaxy (SMG), whereas the remaining three are faint SMGs newly uncovered by ALMA. If we exclude the two brightest sources, the contribution of the ALMA-detected faint SMGs to the infrared extragalactic background light is estimated to be ~ 4.1^{+5.4}_{-3.0} Jy deg^{-2}, which corresponds to ~ 16^{+22}_{-12}% of the infrared extragalactic background light. This suggests that their contribution to the infrared extragalactic background light is as large as that of bright SMGs. We identified multi-wavelength counterparts of the five ALMA sources. One of the sources (SXDF-ALMA3) is extremely faint in the optical to near-infrared region despite its infrared luminosity (L_IR ~ 1e12 L_sun or SFR ~ 100 M_sun yr^{-1}). By fitting the spectral energy distributions (SEDs) at the optical-to-near-infrared wavelengths of the remaining four ALMA sources, we obtained the photometric redshifts (z_photo) and stellar masses (M_*): z_photo ~ 1.3-2.5, M_* ~ (3.5-9.5)e10 M_sun. We also derived their star formation rates (SFRs) and specific SFRs (sSFRs) as ~ 30-200 M_sun yr^{-1} and ~ 0.8-2 Gyr^{-1}, respectively. These values imply that they are main-sequence star-forming galaxies.Comment: PASJ accepted, 15 pages, 6 figures, 2 table

Efficacy and safety of micafungin in empiric and D-index-guided early antifungal therapy for febrile neutropenia ; A subgroup analysis of the CEDMIC trial

Objectives: The D-index is defined as the area over the neutrophil curve during neutropenia. The CEDMIC trial confirmed the noninferiority of D-index-guided early antifungal therapy (DET) using micafungin to empirical antifungal therapy (EAT). In this study, we evaluated the efficacy and safety of micafungin in these settings. Methods: From the CEDMIC trial, we extracted 67 and 113 patients who received micafungin in the DET and EAT groups, respectively. Treatment success was defined as the fulfilment of all components of a five-part composite end point. Fever resolution was evaluated at seven days after the completion of therapy. Results: The proportion of high-risk treatments including induction chemotherapy for acute leukemia and allogeneic hematopoietic stem cell transplantation was significantly higher in the DET group than in the EAT group (82.1% vs. 52.2%). The efficacy of micafungin was 68.7% (95%CI: 56.2–79.4) and 79.6% (71.0–86.6) in the DET and EAT groups, respectively. When we focused on high-risk treatments, the efficacy was 69.1% (55.2–80.9%) and 78.0% (65.3–87.7%), respectively (P = 0.30). There was no significant difference in any of the 5 components between the two groups. Conclusions: The efficacy of micafungin in patients undergoing high-risk treatment was not strongly impaired in DET compared to that in EAT

A pristine record of outer Solar System materials from asteroid Ryugu’s returned sample

Volatile and organic-rich C-type asteroids may have been one of the main sources of Earth’s water. Our best insight into their chemistry is currently provided by carbonaceous chondritic meteorites, but the meteorite record is biased: only the strongest types survive atmospheric entry and are then modified by interaction with the terrestrial environment. Here we present the results of a detailed bulk and microanalytical study of pristine Ryugu particles, brought to Earth by the Hayabusa2 spacecraft. Ryugu particles display a close compositional match with the chemically unfractionated, but aqueously altered, CI (Ivuna-type) chondrites, which are widely used as a proxy for the bulk Solar System composition. The sample shows an intricate spatial relationship between aliphatic-rich organics and phyllosilicates and indicates maximum temperatures of ~30 °C during aqueous alteration. We find that heavy hydrogen and nitrogen abundances are consistent with an outer Solar System origin. Ryugu particles are the most uncontaminated and unfractionated extraterrestrial materials studied so far, and provide the best available match to the bulk Solar System composition

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts