Selection of parameters for advanced machining processes using firefly algorithm

AbstractAdvanced machining processes (AMPs) are widely utilized in industries for machining complex geometries and intricate profiles. In this paper, two significant processes such as electric discharge machining (EDM) and abrasive water jet machining (AWJM) are considered to get the optimum values of responses for the given range of process parameters. The firefly algorithm (FA) is attempted to the considered processes to obtain optimized parameters and the results obtained are compared with the results given by previous researchers. The variation of process parameters with respect to the responses are plotted to confirm the optimum results obtained using FA. In EDM process, the performance parameter “MRR” is increased from 159.70gm/min to 181.6723gm/min, while “Ra” and “REWR” are decreased from 6.21μm to 3.6767μm and 6.21% to 6.324×10−5% respectively. In AWJM process, the value of the “kerf” and “Ra” are decreased from 0.858mm to 0.3704mm and 5.41mm to 4.443mm respectively. In both the processes, the obtained results show a significant improvement in the responses

Investigation of kerf Characteristics in Abrasive Water Jet Machining of Inconel 600 using Response Surface Methodology

Abrasive water jet machining (AWJM) has found its application in the manufacturing industries for machining hard materials with precision. A degree of high precision in machining of complex geometries makes AWJM valuable. The selection of optimum process parameters is important to the resulting quality of machined parts. In this study, an experimental investigation was conducted to evaluate the machinability of Inconel 600. A response surface methodology (RSM) is used to determine the influence of the AWJM process parameters on the considered performance characteristics, i.e., kerf top width (KTW) and taper angle. The analysis of variance is performed to obtain the contribution and influence of each process parameter on the considered responses. The value of R-Squared obtained for KTW and taper angle using regression model is 0.97 and 0.96 respectively. The optimum setting of the parameters for single and multiple response characteristics are obtained using the desirability analysis of RSM. The results obtained using desirability analysis of RSM is validated by conducting the confirmation experiments. The experimental confirmatory values obtained for the considered performance parameters KTW and taper angle as 27.138 and 0.125 respectively. The corresponding value of error obtained as 0.383 and 0.013 respectively. Further, an optimum set is obtained with KTW as 27.461 mm and taper angle as 0.582° for multiple response optimisation

Feeding practices in infants: ritual factors dominating mother’s education - a cross sectional study

Background: The objective was to know the impact of mother education on feeding practices of infants.Methods: Observational analytic cross sectional study. We used Semi-structured, pre-tested questionnaire to interview 355 mothers of infants, aged one and half to 12 months, who came in OPD of Department of Paediatrics UPRIMS and R, Saifai for immunization or some problem.Results: Total 267 (75.2 %) out of 355 women had initiated breast feeding within 24 hours of birth. 172 (48.5%) mothers exclusively breast fed their infants. Total 166 (46.8%) practiced Prelacteal feed. Out of 166 subjects, 121 (34.1%) practiced for 7 days and 41 (12.7%) beyond the 7 days. There were highly significant relationship found between education level of mothers with type of breast feeding, in the form of exclusive or non- exclusive breast feeding and Prelacteal feeding practices ( p 0.05), but an important pattern of initiation of breast feeding was seen at the different level of mothers education.Conclusion: Ritual and customary factors have much impact then mother’s education on breast feeding practices of infants. Apart from education, breast feeding awareness programme should be increased including both literate and illiterate mothers.

SALAD: Source-free Active Label-Agnostic Domain Adaptation for Classification, Segmentation and Detection

We present a novel method, SALAD, for the challenging vision task of adapting a pre-trained "source" domain network to a "target" domain, with a small budget for annotation in the "target" domain and a shift in the label space. Further, the task assumes that the source data is not available for adaptation, due to privacy concerns or otherwise. We postulate that such systems need to jointly optimize the dual task of (i) selecting fixed number of samples from the target domain for annotation and (ii) transfer of knowledge from the pre-trained network to the target domain. To do this, SALAD consists of a novel Guided Attention Transfer Network (GATN) and an active learning function, HAL. The GATN enables feature distillation from pre-trained network to the target network, complemented with the target samples mined by HAL using transfer-ability and uncertainty criteria. SALAD has three key benefits: (i) it is task-agnostic, and can be applied across various visual tasks such as classification, segmentation and detection; (ii) it can handle shifts in output label space from the pre-trained source network to the target domain; (iii) it does not require access to source data for adaptation. We conduct extensive experiments across 3 visual tasks, viz. digits classification (MNIST, SVHN, VISDA), synthetic (GTA5) to real (CityScapes) image segmentation, and document layout detection (PubLayNet to DSSE). We show that our source-free approach, SALAD, results in an improvement of 0.5%-31.3%(across datasets and tasks) over prior adaptation methods that assume access to large amounts of annotated source data for adaptation

Maternal vegetarian diet in pregnancy, a predisposition to hypospadias?

Background: Hypospadias constitutes one of the commonest surgically treated patient subset in a pediatric surgery set up. The causative factors have always been multifactorial. Maternal age and diet during pregnancy have been attempted to be correlated with the prevalence of hypospadias.Methods: The current study aims to find a correlation between the rises of hypospadias with increased maternal vegetarian diet taken during pregnancy. The mothers of patients presenting with hypospadias were allotted structured self-completed questionnaires. Obstetric history, dietary patterns and lifestyle information during pregnancy was obtained.Results: The mothers of patients presenting with hypospadias who had been on a vegetarian diet had an increased incidence of babies presenting with hypospadias as shown in the chart.Conclusions: Diet during gestation may play a role in the etiology of hypospadias. Although this study is limited by less number of cases, it does show the trend of increased incidence of hypospadias amongst vegetarian mothers

Phytochemical evaluation, antioxidant assay, antibacterial activity and determination of cell viability (J774 andTHP1 alpha cell lines) of P. sylvestris leaf crude and methanol purified fractions

Phoenix sylvestris (Arecaceae family) known as Indian Date Palm has been identified as a component of traditional medicine against various ailments. The present study was focused on phytochemical screening of crude hexane, dichloromethane and methanol leaf extracts. The crude extracts showed the presence of alkaloids, flavonoids, and phenols in the plant leaves. In the study methanol extract was found most potent, so this extract was further fractionated by column chromatography and 9 methanol purified fractions (MPFs) were isolated. Most potential MPF8 (20:80 chloroform: methanol ratio fraction) significantly enhanced free radicals and antibacterial activity. The best MIC (Minimum inhibitory concentration) of MPF8 was investigated against M. luteus and E.coli at 1 mg/ml concentration. However, against other bacteria the MIC ranged from 1 mg/ml to 3 mg/ml. The GC-MS analysis showed the presence of many biologically active compounds such as alcohols, flavonoids, aromatic compounds, aldehydes, terpenoids fatty acid methyl esters, and phenolics. Pentadecanoic acid occupied maximum (52 %) area in GC-MS profiling. MPF8 was assayed for in-vitro cytotoxicity by MTT assay which confirms its less cytotoxicity at lower concentration and also significant ROS determination against J774 and THP1 cell lines after 2 and 4 hours

Probiotics in acute diarrhea: A randomized control trial

Background: Probiotics have been used for long in the treatment of acute diarrhea although their efficacy has always remains the subject of discussion. Objective: To determine the effect of probiotics in acute diarrhea among the children in rural population. Method: Double-blinded randomized control trial. We included children of age group 6 months - 5 years suffering from acute diarrhea of <48 h and fulfilling the inclusion criteria. All children were given oral rehydration salts (ORS) ad-lib till the resolution of diarrhea and zinc 20 mg/day for 14 days while intervention arm (n=101) were given probiotic sachet twice a day for 7 days containing Streptococcus faecalis 30 million, Clostridium butyricum 2 million, Bacillus mesentericus 1 million, Lactobacillus sporogenes 50 million, control group were given identical placebo apart from ORS and zinc. Duration of diarrhea in both the groups was measured as primary outcome while secondary outcome was to know the days of maximum recovery from diarrhea in both groups. Results: Totally, 207 patients were randomized to control and study group, out of which, 195 completed the study. Out of total 195 patients, 94 (48.2%) patients were treatedwith standard treatment of diarrhea without probiotics while 101 (51.8%) patients were given probiotics apart from standard treatment of diarrhea. The mean duration of diarrhea was found to be reduced in the study group (4.6 days [2.84-4.776 days]) as compared to control group (5.31 days [5.108-5.512 days]), p<0.001. Conclusion: Probiotics significantly reduced the duration of acute diarrhea in children

A study of mode of transmission, clinical presentations, WHO and immunological staging among HIV infected children

Background: The clinical manifestations of HIV infection vary widely among infants, children, and adolescent. So there is a need to study the mode of transmission, clinical presentations, WHO and immunological staging among HIV infected children.Methods: Observational analytic cross sectional study. The children who were HIV positive (confirmed by ELISA for HIV-1 and HIV-2), and attending the OPD of ART Centre and SN Children Hospital, Allahabad during period of one year. The study population consisted of 47 patients, belonging to both sexes and age of 18 months to 19 years. Detailed history was taken and full clinical examination done in all cases. CD4 count was estimated at the time of presentation.Results: Predominant mode of transmission in our study was vertical and it was present in 95% cases. Fever was the most common presenting complaint and was present in 28 (59.57%) cases. The most common clinical sign was pallor in our study, present in 37 cases (78.72%) followed by lymphadenopathy 34 (72.34%). On the basis of WHO clinical staging, most of the patients in our study were found in stage 2 .On the basis of immunological staging, 51% had no evidence of immunosuppression (stage1), 18 (38.3%) had mild to advanced immunosuppression (stage 2 and 3) and 5 (10.63%) patients were severely immunosuppressed (stage 4). Conclusion: In HIV infected children predominant mode of transmission is vertical. Fever and pallor are common clinical manifestations. Most of the patients are found in WHO clinical stage 2 and immunological stage 1.

Sizes of induration and nutritional status in children with positive Mantoux test

Background: The immune status of children is always affected by nutrition. Sometime severe malnutrition is associated with falsenegative Mantoux test. There is a need to study to observe the effect of nutritional status on the size of indurations in Mantoux positivechildren. Study Design: Observational analytical cross-sectional study. Methods: The study population consisted of 310 patients,belonging to both sexes and age of 1-14 years, attending the outpatient department of UP Rural Institute of Medical Sciences andResearch, Saifai, Etawah. Only Mantoux positive cases were included in the study. Their sizes of indurations of skin reaction weremeasured and recorded in mm. The nutritional status was calculated as the weight for age and height for age standard (Z-score), usingthe NCHS charts of for males and females. Results: Out of 800 children screened for tuberculosis, 310 children had positive Mantouxtest and were recruited in the study. Mean induration (20 mm) was similar in all the groups. However, the size of indurations rangedfrom 10-40 mm, 11-33 mm, and 12-24 among normal weight, underweight, and overweight Z-score groups. Mean induration was same(20 mm) in two Z-score height for age groups (normal height, stunting), while it was 20.6 mm in the over-height group. Although, therange of Mantoux positivity ranges from 10-35 mm, 11-40 mm, and 18-22 mm among normal height, stunting, and over height Z-scoregroups. Conclusion: Although, nutritional status can affect the positivity of Mantoux test; in Mantoux positive children, the size ofindurations does not depend on their nutritional status