Additional file 1: of 1000 human genomes carry widespread signatures of GC biased gene conversion

Instruction manual for Perl programs for testing BGC hypothesis. This file contains detailed instructions and protocols of Perl programs for construction and analysis of haplotypes of frequent genetic variants. (DOCX 334 kb

El Diario de Pontevedra : periódico liberal: Ano XXX Número 8766 - 1913 xullo 24

A prototype of one of the output files generated in Step II. The name of the file is STAT_FOR_Mos_New_1 which is for chromosome 1. The file is transferred from UNIX to pc environment in MS Excel format. (XLSX 98 kb

Additional file 7: Table S3. of Intricacies in arrangement of SNP haplotypes suggest “Great Admixture” that created modern humans

A prototype of one of the output files generated in Step II. The name of the file is STAT_FOR_Yin_Yang_New_1 which is for chromosome 1. The file is transferred from UNIX to pc environment in MS Excel format. (XLSX 50 kb

Additional file 6: Table S2. of Intricacies in arrangement of SNP haplotypes suggest “Great Admixture” that created modern humans

A prototype of one of the output files generated in Step II. The name of the file is CORE_HAPS_New_140 which is for chromosome 1 segment 140. The file is transferred from UNIX to pc environment in MS Excel format. (XLSX 23 kb

Additional file 1: of RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs

Tables S1, S2, S3, S4, S5 and S6. Table S1. This table provides: a) Gene-specific assay information including SNP sites, primer and internal standard sequences, b) Subject-specific demographic information, and c) assay- and subject-specific transcript abundance values (target gene molecules/106 ACTB molecules). Table S2. Population used for allele specific expression analysis: Summary demographic characteristics of the study population of allele specific expression (subject total n = 180). Table S3. Transcription factor-target inter-gene correlation in Control, COPD, or All subjects (p-value < 0.05). Table S4. Analysis of covariance (ANCOVA). Gene expression values (Independent Variables) significantly correlated (positively or negatively) with COPD subjects (Dependent Variable) after control for expression values of other genes (Covariates). Table S5. ERCC5 SNPs linked to rs17655 and rs873601 (D > 0.95) and with p < 0.05 in LHS and COPDgene NHW CB cohorts. COPD GWAS p-values, population-specific genotype frequencies, and epigenetic annotation information from Haploreg/Encode. Table S6. Haplotype structure between COPDgene NHW1 associated SNP rs4150275, putative functional cis-rSNP rs873601, and DAE2 SNP rs17655. (XLSX 109 kb