One-Step Preparation of High Performance TiO 2 /CNT/CQD Nanocomposites Bactericidal Coating with Ultrasonic Radiation

© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).As an environmental semiconductor material, TiO2 has important applications in the fields of environmental protection and water treatment. The preparation of P25 particles into nano-functional material films with a high specific surface area has always been a bottleneck limiting its large-scale application. In this paper, a one-step method of preparing TiO2 nanocomposites by doping carbon nanotube (CNT) and carbon quantum dots (CQD) with tetrabutyltitanate and P25 TiO2 under ultrasonic radiation is proposed to synthesize a novel antifouling material, which both eliminates the bacterium of Escherichia coli and shows good photoelectric properties, indicating a great value for the industrial promotion of TiO2/CNT. This mesoporous composite exhibits a high specific surface area of 78.07 M2/g (BET) and a tested pore width range within 10–120 nm. The surface morphology of this composite is characterized by TEM and the microstructure is characterized through XRD. This preparation method can fabricate P25 particles into a nano-functional material film with a high specific surface area at a very low cost.Peer reviewe

GeneCAI: Genetic Evolution for Acquiring Compact AI

In the contemporary big data realm, Deep Neural Networks (DNNs) are evolving towards more complex architectures to achieve higher inference accuracy. Model compression techniques can be leveraged to efficiently deploy such compute-intensive architectures on resource-limited mobile devices. Such methods comprise various hyper-parameters that require per-layer customization to ensure high accuracy. Choosing such hyper-parameters is cumbersome as the pertinent search space grows exponentially with model layers. This paper introduces GeneCAI, a novel optimization method that automatically learns how to tune per-layer compression hyper-parameters. We devise a bijective translation scheme that encodes compressed DNNs to the genotype space. The optimality of each genotype is measured using a multi-objective score based on accuracy and number of floating point operations. We develop customized genetic operations to iteratively evolve the non-dominated solutions towards the optimal Pareto front, thus, capturing the optimal trade-off between model accuracy and complexity. GeneCAI optimization method is highly scalable and can achieve a near-linear performance boost on distributed multi-GPU platforms. Our extensive evaluations demonstrate that GeneCAI outperforms existing rule-based and reinforcement learning methods in DNN compression by finding models that lie on a better accuracy-complexity Pareto curve

Association between ecological risks and ecosystem services in an urban agglomeration in arid China

Rapid urbanization leads to changes in ecosystem services and may exacerbate ecological risks. Clarifying the relationship between these two factors in a specific context is essential to explore the integrated management model and achieve sustainable regional development. However, previous studies mainly lack an integrated analysis, fail to clearly explain the mechanism of ecosystem change, and can neither support landscape ecological security construction nor spatial planning and management. This study, using the urban agglomeration on the northern slope of the Tianshan Mountains (UANSTM) as an example, applied multi-source data from 2010 to 2020, investigated the changes and relationships between ecological risks and ecosystem services, and proposes an assessment framework. The total ecosystem services (TES) of the studied agglomeration showed a decreasing trend, with an overall loss of 0.43%. Corresponding to the decrease of ecosystem services, the ecological risk was higher in the south and north of the UANSTM and lower in the northwestern, central, and eastern regions. The proportion of ecological high-risk areas was expanding. The key to the relationship between ecological risks and ecosystem services is the change in hydrological conditions. Therefore, we suggest that the UANSTM actively transforms the development and use mode of water resources and coordinates their allocation, aiming to reduce regional ecological risks and optimize the pattern of ecosystem services

Enhanced immune reconstitution with albuvirtide in HIV-infected immunological non-responders

BackgroundIncomplete immune recovery in people living with HIV/AIDS (PLWHA) remains an important clinical challenge with the lack of an effective strategy currently available to restore their T-cell immune response. This study aimed to evaluate the effect of Albuvirtide (ABT) on immune recovery in immunological non-responders (INRs) and attempted to explore potential mechanisms of ABT on the functionality of immune cells.MethodsIn this prospective, open-label, controlled clinical study, participants with incomplete immune reconstitution (continuous ART over 5 years and CD4+T lymphocyte absolute count of <500 cells/µl or ART for 2–5 years and CD4+T cell count of <200 cells/µl with undetectable viral load) were received intensive treatment with ABT or maintained on the original ART regimen at a ratio of 1:1. Immune response and safety were examined within 24 weeks. In the cytological study, T subsets, cell apoptosis and cell autophagy were analyzed using immunofluorescence staining and flow cytometry from 25 blood specimens.ResultsBoth groups (n=25 each) were comparable in age, gender, and ART duration. At week 12, CD4+T cell count increased significantly in the intensive ABT group compared with control group (the change from baseline in CD4+T cell count: 45 vs. -5 cells/µL, p<0.001). After ABT discontinuation, CD4+T cell counts remained significantly higher in the intensive ABT group at week 24 (55 vs. -5 cells/µL, p=0.012). In laboratory analysis, naïve CD4+ T cell amounts were lowest among participants with unsatisfactory immune response (uIR) to ABT (p=0.001). The proportion of caspase 3+CD45RA+CD31+CD4+ T cells was significantly lower in participants with satisfactory immune response (sIR) to ABT (p<0.05).ConclusionSignificant CD4+T cell count increase suggests ABT enhances immune function in INRs which may be attributed to its antiviral properties as well as its ability to increase thymic cell output and decrease cell apoptosis

Surface functionalization of vertical graphene significantly enhances the energy storage capability for symmetric supercapacitors

Vertical graphene (VG) sheets, which consist of few-layer graphene vertically aligned on the substrate with three dimensionally interconnected porous network, make them become one of the most promising energy storage electrodes, especially for SCs. Nevertheless, the intrinsic hydrophobic nature of pristine VG sheets severely limited its application in aqueous SCs. Here, electrochemical oxidation strategy is adopted to increase the hydrophilicity of VG sheets by introducing oxygen functional groups so that the aqueous electrolyte can fully be in contact with the VG sheets to improve charge storage performance. Our work demonstrated that the introduction of oxygen functional groups not only greatly improved the hydrophilicity but also generated a pseudo capacitance to increase the specific capacitance. The resulting capacitance of electrochemically oxidized VG for 7 min (denoted as EOVG-7) exhibited three orders of magnitude higher (1605 mF/cm²) compared to pristine VG sheets. Through assembled two EOVG-7 electrodes, a symmetric supercapacitor demonstrated high specific capacitance of 307.5 mF/cm², high energy density of 138.3 μWh/cm2 as well as excellent cyclic stability (84% capacitance retention after 10000 cycles). This strategy provides a promising way for designing and engineering carbon-based aqueous supercapacitors with high performance

Calculation for Acoustic Radiation Force from Rectangular Weakly Focusing Transducer Using the Ray Acoustic Model

Based on the ray acoustic model, a new relationship between the radiation force and the acoustic power is studied for a rectangular weakly focusing transducer. The effect of pressure reflection coefficient on this model is discussed. For a totally absorbing target, an approximate closed-form expression is also derived and the performance of this model is compared with that of the far-field integration model. The numerical results show that the agreement is excellent with these two models, which can be both used for correction of measured results, but the formula based on the ray acoustic model can be applied more widely in practice because of its simpler expression. The experimental results show further the effectiveness of the relationship between radiation force and acoustic power for rectangular weakly focusing transducer based on the ray acoustic model. The results presented in this paper are important for application of ultrasound transducers in therapy

Strengthening mechanism based on dislocation-twin interaction under room temperature multi-directional forging of AZ80 Mg alloy

Twin and dislocation have critical influence on the mechanical properties of the widely used AZ80 magnesium alloy. In the present work, we designed room temperature multi-direction forging (MDF) at different strain amplitudes (3% and 6%) with a same strain, introduced twin and dislocation structures and improved the mechanical properties of the alloy. The results showed that the material reached the limit of deformation with a cumulative strain of 0.72. With the increase of strain, the grain size decreased and the dislocation density increased gradually. At low strain amplitude, the transformation of dislocations at twin boundaries (TBs) caused twinning expansion and detwinning. While at high strain amplitude, interactive twin structure hindered the over-expansion of twins. In addition, high-density dislocations accumulate at the twin boundaries, which stimulates the nucleation of twin variants and further refines the grains. In the process of plastic deformation, dislocation strengthening contributed the main yield strength, and fine twins provided a certain level of hardening ability. Through the interaction between the dislocations and twins, the strength and plasticity of the material were synergistically improved, and excellent mechanical properties with ultimate tensile strength of 486 MPa, yield strength of 385 MPa, and elongation of 8.1% were finally obtained