Genetic Algorithms Based Economic Dispatch with Application to Coordination of Nigerian Thermal Power Plants

The main focus of this paper is on the application of genetic algorithm (GA) to search for an optimal solution to a realistically formulated economic dispatch (ED) problem. GA is a global search technique based on principles inspired from the genetic and evolution mechanism observed in natural biological systems. A major drawback of the conventional GA (CGA) approach is that it can be time consuming. The micro-GA (µGA) approach has been proposed as a better time efficient alternative for some engineering problems. The effectiveness of CGA and µGA. to solving ED problem is initially verified on an IEEE 3-generating unit, 6-bus test system. Simulation results obtained on this network using CGA and µGA validate their effectiveness when compared with the published results obtained via the classical and the Hopfield neural network approaches. Finally, both GA approaches have been successfully applied to the coordination of the Nigerian 31-bus system fed by four thermal and three hydro generating units. Herein, use has been made of the loss formula developed for the Nigerian system from several power flow studies. For the Nigerian case study, the µGA. is shown to exhibit superior performance than the CGA from both optimal generation allocations and computational time viewpoints

Federated Learning Enables Big Data for Rare Cancer Boundary Detection

Although machine learning (ML) has shown promise across disciplines, out-of-sample generalizability is concerning. This is currently addressed by sharing multi-site data, but such centralization is challenging/infeasible to scale due to various limitations. Federated ML (FL) provides an alternative paradigm for accurate and generalizable ML, by only sharing numerical model updates. Here we present the largest FL study to-date, involving data from 71 sites across 6 continents, to generate an automatic tumor boundary detector for the rare disease of glioblastoma, reporting the largest such dataset in the literature (n = 6, 314). We demonstrate a 33% delineation improvement for the surgically targetable tumor, and 23% for the complete tumor extent, over a publicly trained model. We anticipate our study to: 1) enable more healthcare studies informed by large diverse data, ensuring meaningful results for rare diseases and underrepresented populations, 2) facilitate further analyses for glioblastoma by releasing our consensus model, and 3) demonstrate the FL effectiveness at such scale and task-complexity as a paradigm shift for multi-site collaborations, alleviating the need for data-sharing