36 research outputs found
Localisation of gamma-ray interaction points in thick monolithic CeBr3 and LaBr3:Ce scintillators
Localisation of gamma-ray interaction points in monolithic scintillator
crystals can simplify the design and improve the performance of a future
Compton telescope for gamma-ray astronomy. In this paper we compare the
position resolution of three monolithic scintillators: a 28x28x20 mm3 (length x
breadth x thickness) LaBr3:Ce crystal, a 25x25x20 mm3 CeBr3 crystal and a
25x25x10 mm3 CeBr3 crystal. Each crystal was encapsulated and coupled to an
array of 4x4 silicon photomultipliers through an optical window. The
measurements were conducted using 81 keV and 356 keV gamma-rays from a
collimated 133Ba source. The 3D position reconstruction of interaction points
was performed using artificial neural networks trained with experimental data.
Although the position resolution was significantly better for the thinner
crystal, the 20 mm thick CeBr3 crystal showed an acceptable resolution of about
5.4 mm FWHM for the x and y coordinates, and 7.8 mm FWHM for the z-coordinate
(crystal depth) at 356 keV. These values were obtained from the full position
scans of the crystal sides. The position resolution of the LaBr3:Ce crystal was
found to be considerably worse, presumably due to the highly diffusive optical
in- terface between the crystal and the optical window of the enclosure. The
energy resolution (FWHM) measured for 662 keV gamma-rays was 4.0% for LaBr3:Ce
and 5.5% for CeBr3. The same crystals equipped with a PMT (Hamamatsu R6322-100)
gave an energy resolution of 3.0% and 4.7%, respectively
Upconversion channels in Er3+:ZBLALiP fluoride glass microspheres
We present results on the realization of a multicolour microspherical glass light source fabricated from the erbium doped fluoride glass ZBLALiP. Whispering gallery mode lasing and upconversion processes give rise to laser and fluorescent emissions at multiple wavelengths from the ultraviolet to the infrared. Thirteen discrete emissions ranging from 320 to 849 nm have been observed in the upconversion spectrum. A Judd-Ofelt analysis was performed to calculate the radiative properties of Er3+:ZBLALiP microspheres, including the radiative transition probabilities, the electric dipole strengths, the branching ratios and the radiative lifetimes of the transitions involved. We have also identified the primary processes responsible for the generation of the observed wavelengths and have shown that this material has an improved range of emissions over other erbium doped fluoride glasses
A heat-and-pull rig for fiber taper fabrication
We describe a reproducible method of fabricating adiabatic tapers with 3-4
micron diameter. The method is based on a heat-and-pull rig, whereby a CO2
laser is continuously scanned across a length of fiber that is being pulled
synchronously. Our system relies on a CO2 mirror mounted on a geared stepper
motor in order to scan the laser beam across the taper region. We show that
this system offers a reliable alternative to more traditional rigs
incorporating galvanometer scanners. We have routinely obtained transmission
losses between 0.1 and 0.3 dB indicating the satisfactory production of
adiabatic tapers. The operation of the rig is described in detail and an
analysis on the produced tapers is provided. The flexibility of the rig is
demonstrated by fabricating prolate dielectric microresonators using a
microtapering technique. Such a rig is of interest to a range of fields that
require tapered fiber fabrication such as microcavity-taper coupling, atom
guiding along a tapered fiber, optical fiber sensing and the fabrication of
fused biconical tapered couplers.Comment: 13 pages, 6 figures Submitted to Rev. Sci. Instru
The Athena x-ray optics development and accommodation
The Athena mission, under study and preparation by ESA as its second Large-class science mission, requires the largest X-ray optics ever flown, building on a novel optics technology based on mono crystalline silicon. Referred to as Silicon Pore Optics technology (SPO), the optics is highly modular and benefits from technology spin-in from the semiconductor industry. The telescope aperture of about 2.5 meters is populated by around 700 mirror modules, accurately co-aligned to produce a common focus. The development of the SPO technology is a joint effort by European industrial and research entities, working together to address the challenges to demonstrate the imaging performance, robustness and efficient series production of the Athena optics. A technology development plan was established and is being regularly updated to reflect the latest developments, and is fully funded by the ESA technology development programmes. An industrial consortium was formed to ensure coherence of the individual technology development activities. The SPO technology uses precision machined mirror plates produced using the latest generation top quality 12 inch silicon wafers, which are assembled into rugged stacks. The surfaces of the mirror plates and the integral support structure is such, that no glue is required to join the individual mirror plates. Once accurately aligned with respect to each other, the surfaces of the mirror plates merge in a physical bonding process. The resultant SPO mirror modules are therefore very accurate and stable and can sustain the harsh conditions encountered during launch and are able to tolerate the space environment expected during operations. The accommodation of the Athena telescope is also innovative, relying on a hexapod mechanism to align the optics to the selected detector instruments located in the focal plane. System studies are complemented by dedicated technology development activities to demonstrate the capabilities before the adoption of the Athena mission
The dual PI3K/mTOR inhibitor NVP-BEZ235 inhibits proliferation and induces apoptosis of burkitt lymphoma cells
Simulating the optical performances of the ATHENA x-ray telescope optics
The ATHENA (Advanced Telescope for High Energy Astrophysics) X-ray observatory is an ESA-selected L2 class mission. In the proposed configuration, the optical assembly has a diameter of 2.2 m with an effective area of 1.4 m2 at 1 keV, 0.25 m2 at 6 keV, and requires an angular resolution of 5 arcsec. To meet the requirements of effective area and angular resolution, the technology of Silicon Pore Optics (SPO) was selected for the optics implementation. The ATHENA's optic assembly requires hundreds of SPOs mirror modules (MMs), obtained by stacking wedged and ribbed silicon wafer plates onto silicon mandrels to form the Wolter-I configuration. Different factors can contribute to limit the imaging performances of SPOs, such as i) diffraction through the pore apertures, ii) plate deformations due to fabrication errors and surface roughness, iii) alignment errors among plates in an MM, and iv) co-focality errors within the MMs assembly. In order to determine the fabrication and assembling tolerances, the impact of these contributions needs to be assessed prior to manufacturing. A set of simulation tools responding to this need was developed in the framework of the ESA-financed projects SIMPOSIuM and ASPHEA. In this paper, we present the performance simulation obtained for the recentlyproposed ATHENA configuration in terms of effective area, and we provide a simulation of the diffractive effects in a pair of SPO MMs. Finally, we present an updated sizing of magnetic diverter (a Halbach array) and the magnetic fields levels that can be reached in order to deviate the most energetic protons out of the detector field
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
The seeds of divergence: the economy of French North America, 1688 to 1760
Generally, Canada has been ignored in the literature on the colonial origins of divergence with most of the attention going to the United States. Late nineteenth century estimates of income per capita show that Canada was relatively poorer than the United States and that within Canada, the French and Catholic population of Quebec was considerably poorer. Was this gap long standing? Some evidence has been advanced for earlier periods, but it is quite limited and not well-suited for comparison with other societies.
This thesis aims to contribute both to Canadian economic history and to comparative work on inequality across nations during the early modern period. With the use of novel prices and wages from Quebec—which was then the largest settlement in Canada and under French rule—a price index, a series of real wages and a measurement of Gross Domestic Product (GDP) are constructed. They are used to shed light both on the course of economic development until the French were defeated by the British in 1760 and on standards of living in that colony relative to the mother country, France, as well as the American colonies.
The work is divided into three components. The first component relates to the construction of a price index. The absence of such an index has been a thorn in the side of Canadian historians as it has limited the ability of historians to obtain real values of wages, output and living standards. This index shows that prices did not follow any trend and remained at a stable level. However, there were episodes of wide swings—mostly due to wars and the monetary experiment of playing card money. The creation of this index lays the foundation of the next component.
The second component constructs a standardized real wage series in the form of welfare ratios (a consumption basket divided by nominal wage rate multiplied by length of work year) to compare Canada with France, England and Colonial America. Two measures are derived. The first relies on a “bare bones” definition of consumption with a large share of land-intensive goods. This measure indicates that Canada was poorer than England and Colonial America and not appreciably richer than France. However, this measure overestimates the relative position of Canada to the Old World because of the strong presence of land-intensive goods. A second measure is created using a “respectable” definition of consumption in which the basket includes a larger share of manufactured goods and capital-intensive goods. This second basket better reflects differences in living standards since the abundance of land in Canada (and Colonial America) made it easy to achieve bare subsistence, but the scarcity of capital and skilled labor made the consumption of luxuries and manufactured goods (clothing, lighting, imported goods) highly expensive. With this measure, the advantage of New France over France evaporates and turns slightly negative. In comparison with Britain and Colonial America, the gap widens appreciably. This element is the most important for future research. By showing a reversal because of a shift to a different type of basket, it shows that Old World and New World comparisons are very sensitive to how we measure the cost of living. Furthermore, there are no sustained improvements in living standards over the period regardless of the measure used. Gaps in living standards observed later in the nineteenth century existed as far back as the seventeenth century. In a wider American perspective that includes the Spanish colonies, Canada fares better.
The third component computes a new series for Gross Domestic Product (GDP). This is to avoid problems associated with using real wages in the form of welfare ratios which assume a constant labor supply. This assumption is hard to defend in the case of Colonial Canada as there were many signs of increasing industriousness during the eighteenth and nineteenth centuries. The GDP series suggest no long-run trend in living standards (from 1688 to circa 1765). The long peace era of 1713 to 1740 was marked by modest economic growth which offset a steady decline that had started in 1688, but by 1760 (as a result of constant warfare) living standards had sunk below their 1688 levels. These developments are accompanied by observations that suggest that other indicators of living standard declined. The flat-lining of incomes is accompanied by substantial increases in the amount of time worked, rising mortality and rising infant mortality. In addition, comparisons of incomes with the American colonies confirm the results obtained with wages— Canada was considerably poorer.
At the end, a long conclusion is provides an exploratory discussion of why Canada would have diverged early on. In structural terms, it is argued that the French colony was plagued by the problem of a small population which prohibited the existence of scale effects. In combination with the fact that it was dispersed throughout the territory, the small population of New France limited the scope for specialization and economies of scale. However, this problem was in part created, and in part aggravated, by institutional factors like seigneurial tenure. The colonial origins of French America’s divergence from the rest of North America are thus partly institutional