42 research outputs found
Doppler radar with multiphase modulation of transmitted and reflected signal
A microwave radar signal is generated and split by a circulator. A phase shifter introduces a series of phase shifts into a first part of the split signal which is then transmitted by antenna. A like number of phase shifts is introduced by the phase shifter into the return signal from the target. The circulator delivers the phase shifted return signal and the leakage signal from the circulator to a mixer which generates an IF signal output at the Doppler frequency. The IF signal is amplified, filtered, counted per unit of time, and the result displayed to provide indications of target sense and range rate. An oscillator controls rate of phase shift in the transmitted and received radar signals and provides a time base for the counter. The phase shift magnitude increases may be continuous and linear or discrete functions of time
Method and apparatus for measuring distance
The invention employs a continuous wave radar technique and apparatus which can be used as a distance measuring system in the presence of background clutter by utilizing small passive transponders. A first continuous electromagnetic wave signal S sub 1 at a first frequency f sub 1 is transmitted from a first location. A transponder carried by a target object positioned at a second (remote) location receives the transmitted signal, phase-coherently divides the f sub 1 frequency and its phase, and re-transmits the transmitted signal as a second continuous electromagnetic wave signal S sub 2 at a lower frequency f sub 2 which is a subharmonic of f sub 1. The re-transmitted signal is received at the first location where a measurement of the phase difference is made between the signals S sub 1 and S sub 2, such measuremnt being indicative of the distance between the first and second locations
Method and apparatus for measuring frequency and phase difference
A system for deriving direct digital indications of frequency and phase difference between two incoming pulse trains adaptable for collision avoidance systems or the like. A pair of radar beams 152 and 152A are directed toward a target 153 and corresponding beams 154 and 154A returning therefrom are detected. A digital difference circuit 110 forms a pulse train 66 from the Doppler shift frequencies of each beam pair having a repetition rate functionally related to the difference in magnitude of the shift frequencies. Pulses from the pulse train are counted as a function of time. Visual indications thereof on display 144 are correlative to target position relative to beams 152 and 152A
Mutation of the phospholipase C-γ1–binding site of LAT affects both positive and negative thymocyte selection
Linker for activation of T cells (LAT) is a scaffolding adaptor protein that is critical for T cell development and function. A mutation of LAT (Y136F) that disrupts phospholipase C-γ1 activation and subsequent calcium influx causes a partial block in T cell development and leads to a severe lymphoproliferative disease in homozygous knock-in mice. One possible contribution to the fatal disease of LAT Y136F knock-in mice could be from autoreactive T cells generated in these mice because of altered thymocyte selection. To examine the impact of the LAT Y136F mutation on thymocyte positive and negative selection, we bred this mutation onto the HY T cell receptor (TCR) transgenic, recombination activating gene-2 knockout background. Female mice with this genotype showed a severe defect in positive selection, whereas male mice exhibited a phenotype resembling positive selection (i.e., development and survival of CD8(hi) HY TCR-specific T cells) instead of negative selection. These results support the hypothesis that in non-TCR transgenic, LAT Y136F knock-in mice, altered thymocyte selection leads to the survival and proliferation of autoreactive T cells that would otherwise be negatively selected in the thymus