The platelet activation induced by wheat germ agglutinin

AbstractIn human platelets, wheat germ agglutinin (WGA) induced serotonin release without cell agglutination. WGA induced the phosphorylation of both 40-kDa and 20-kDa proteins in a parallel manner, and at least, the phosphorylation of 40-kDa protein was preceded by transient formation of endogenous diacylglycerol (DG) accompanied by a decrease in phosphatidylinositol (PI). Both phosphorylation of these two proteins and serotonin release were inhibited by prior treatment of platelets with dibutyryl cyclic AMP, W-7, or TMB-8. These results suggest that both phosphatidylinositol turnover and Ca2+ mobilization play an essential role in WGA-induced platelet activation

Angle-Resolved Photoelectron Spectrometer for the Use of Surface Study of Solids

An angle-resolved photoelectron spectrometer constructed recently in our laboratory is described in detail, which comprises mainly from an electron energy analyser movable in situ from the outside of an ultra-high-vacuum (UHV) chamber, an UV light source and a sample manipulator. An ion-pump system is used to evacuate the chamber up to better vaccum than 10^ Torr. Several other auxiliary equipments such as LEED, RHEED and/or RMEED apparatus, Ar^+ ionbombardment and/or sample cleaving systems, a mass spectrometer and a gas inlet system are installed in the chamber. Some obtained results by the apparatus are shown as the typical examples in order to demonstrate the high performance attained

Missing ophiolitic rocks along the Mae Yuam Fault as the Gondwana-Tethys divide in north-west Thailand

Thailand comprises two continental blocks: Sibumasu and Indochina. The clastic rocks of the Triassic Mae Sariang Group are distributed in the Mae Hong Son-Mae Sariang area, north-west Thailand, which corresponds to the central part of Sibumasu. The clastic rocks yield abundant detrital chromian spinels, indicating a source of ultramafic/mafic rocks. The chemistry of the detrital chromian spinels suggests that they were derived from three different rock types: ocean-floor peridotite, chromitite and intraplate basalt, and that ophiolitic rocks were exposed in the area, where there are no outcrops of them at present. Exposition of an ophiolitic complex denotes a suture zone or other tectonic boundary. The discovery of chromian spinels suggests that the Gondwana-Tethys divide is located along the Mae Yuam Fault zone. Both paleontological and tectonic aspects support this conclusion. © 2004 Blackwell Publishing Asia Pty Ltd

Corundum-bearing mafic granulites in the Horoman (Japan) and Ronda (Spain) peridotite massifs: Possible remnants of recycled crustal materials in the mantle

金沢大学理工研究域自然システム学