A Computational Approach to a Mathematical Model of Climate Change Using Heat Sources and Diffusion

The present work aims to extend the climate change energy balance models using a heat source. An ordinary differential equations (ODEs) model is extended to a partial differential equations (PDEs) model using the effects of diffusion over the spatial variable. In addition, numerical schemes are presented using the Taylor series expansions. For the climate change model in the form of ODEs, a comparison of the presented scheme is made with the existing Trapezoidal method. It is found that the presented scheme converges faster than the existing scheme. Also, the proposed scheme provides fewer errors than the existing scheme. The PDEs model is also solved with the presented scheme, and the results are displayed in the form of different graphs. The impact of the climate feedback parameter, the heat uptake parameter of the deep ocean, and the heat source parameter on global mean surface temperature and deep ocean temperature is also portrayed. In addition, these recently developed techniques exhibit a high level of predictability. Doi: 10.28991/CEJ-2022-08-07-04 Full Text: PD

Numerical Schemes for Fractional Energy Balance Model of Climate Change with Diffusion Effects

This study aims to propose numerical schemes for fractional time discretization of partial differential equations (PDEs). The scheme is comprised of two stages. Using von Neumann stability analysis, we ensure the robustness of the scheme. The energy balance model for climate change is modified by adding source terms. The local stability analysis of the model is presented. Also, the fractional model in the form of PDEs with the effect of diffusion is given and solved by applying the proposed scheme. The proposed scheme is compared with the existing scheme, which shows a faster convergence of the presented scheme than the existing one. The effects of feedback, deep ocean heat uptake, and heat source parameters on global mean surface and deep ocean temperatures are displayed in graphs. The current study is cemented by the fact-based popular approximations of the surveys and modeling techniques, which have been the focus of several researchers for thousands of years.Mathematics Subject Classification:65P99, 86Axx, 35Fxx. Doi: 10.28991/ESJ-2023-07-03-011 Full Text: PD

Macroeconomic Determinants of Urbanization in Pakistan

Urbanization refers to the migration of rural people to urban centers in search of better jobs. Urbanization and growth go together; no country has ever reached middle-income status without a significant population shift into cities. Urbanization has strong association with unemployment, economic growth, poverty, infrastructure, crimes, health, socio-economic conditions and education. In 2050, most of the urban population of the world will be concentrated in Asia (52%) and in Africa (21%). A simple and modest model provided reasonable results. Increase in literacy is a decisive factor that has significant impact on increasing urban population. Per capita GDP growth also positively influences the urban population. Age-structure is too an important determinant of migration and urbanization. It is an open secret that generally young persons have gone abroad. Specification and diagnostics test supported the model which reveals appropriateness and statistical soundness of the model. Serious heed is paid to delimitation of cities to make them manageable and governable. Agriculture is provided sufficient resources to discourage migration to cities

1,3-Bis(1-cyclo­hexyl­eth­yl)imidazolidine-2-thione

The complete mol­ecule of the title compound, C19H34N2S, is generated by crystallographic twofold symmetry, with the C=S group lying on the rotation axis. A short C—H⋯S contact occurs in the mol­ecule. The five-membered ring is twisted and the cyclo­hexyl ring adopts a chair conformation. The dihedral angle between the mean plane of the five-membered ring and the basal plane of the cyclo­hexyl ring is 75.32 (13)°

Impact of PUBG Game Addiction on Social Isolation and Narcissistic Tendencies among Gamers

The current research aimed to explore the relationship of PUBG game addiction with narcissistic tendencies and social isolation in gamers. For this correlation survey based research the data was conveniently collected from PUBG gamers (N= 101) age ranging from 13-30 years through online response method. The instruments included Online Game Addiction Scale (Kim, Namkoong, Ku, & Kim, 2008) Narcissistic Personality Inventory (Raskin & Hall, 1981) and Measures of Social Isolation (Zavaleta, Samuel, & Mills, 2017) for testing the hypothesis. According to the yielded results, an excellent reliability of these measures was established. The results also indicated that online game addiction, social isolation and narcissistic tendencies among PUBG game players are negatively correlated (<.05). It was concluded that online games do carry positive aspects of enhancing social skills and interactions among the players, while helping them exhibit behaviors and emotions that are not coherent with narcissistic tendencies. This paper also carries implications for families, friends, teachers and therapists of online gamers, who may use the findings to understand some of the positive aspects of playing online games

Effectiveness of clean intermittent self catheterization in patients with recurrent urethral stricture post visual internal urethrotomy

OBJECTIVE :   Objective of the study is to determine the effectiveness of CISC in management of recurrent urethral strictures after visual internal urethrotomy.  METHODOLOGY :  This study   performed in department of urology   Saidu teaching hospital Swat  from June 2016 to July 2019 on 215 patients who were diagnosed as having urethral stricture disease. Patients were counseled  for CISC after removal of catheter 2 times a day for 8 weeks  and  at 8th  week cystourethroscopy performed along with detail  evaluation of symptoms of urethral stricture to know  recurrence of stricture.  RESULTS:   81.39% patients have no urethral stricture on cystourethroscopy  and symptomatic evaluation at 8th week  post visual internal urethrotomy  while 18.60%  patients have recurrent urethral stricture . Length of urethral stricture is the most important prognostic factor, stricture of less than 1 cm has success rate of 62.39% while stricture of more than one cm length has success rate of 20% as shown in table IV.  CONCLUSION:  In this study it has been confirmed that CISC  is safe ,cost effective procedure and most of the patients can do it in home with out any complications.

Idiopathic multicentric Castleman disease: a mysterious case of generalized lymphadenopathy

Castleman disease is a syndrome with significant clinico-pathological overlap between malignancy, autoimmune causes and infectious etiologies. It is a spectrum and can vary in extent from unicentric to multicentric disease with generalized lymphadenopathy, organ involvement, constitutional symptoms and cytopenias, and in severity from non-severe to severe disease with TAFRO symptoms. Idiopathic multicentric Castleman disease (iMCD) is a diagnosis of exclusion after multiple causes as per diagnostic criteria are excluded. Treatment varies between the disease severity types with anti-IL 6 antibodies for non-severe disease to cytotoxic chemotherapy agents for severe disease with TAFRO symptoms. We hereby report a case of a non-severe type of iMCD with a prolonged course and delayed arrival at the diagnosis, owing to the rarity of this condition, which stresses the need for a reduced threshold to consider MCD, early in the differential diagnosis. Interestingly there were positive auto-antibodies and elevated IgG4 levels in this patient, but applying strict criteria helps to distinguish the diagnosis

Molecular classification of breast cancer using IHC markers: experience from a tertiary cancer center in south India

Background: Breast cancer is a very heterogeneous disease. Molecular or intrinsic subtypes of breast cancer are based on the gene expression profiling. Doing gene expression profiling in each case is practically difficult. So most of the labs depend on immunohistochemistry to classify breast tumors into various molecular-like subtypes. In this study, we have used immune histochemistry to classify tumors into various subtypes. Methods: We have retrospectively collected the data of breast cancer patients treated at Apollo Cancer Center, Chennai, in whom ER, PR, HER 2 Neu and Ki 67 were done, and the data was analyzed. Results: The commonest molecular subtype observed in the present study was Luminal B HER2 positive, constituting 40% of the cases, followed by a HER2 positive (non-luminal) subtype in 20% of cases. The triple negative subtype was the third most frequent, comprising 18% of the cases. The least frequent subtype was Luminal A, seen in only 8% of cases. Conclusions: There is a higher proportion of luminal B HER2 positive and triple negative subtypes in our study population compared to the other studies in published literature. The proportion of luminal A was lesser in our study compared to the literature

1,3-Bis(1-phenyl­eth­yl)imidazolidine-2-thione

The complete molecule of the title compound, C19H22N2S, is generated by crystallographic twofold symmetry with the C=S group lying on the rotation axis. The imidazolidine ring adopts a flattened twist conformation. The dihedral angle between the asymmetric part of the imidazolidine-2-thione fragment and the benzene ring is 89.49 (17)°