Study of antepartum hemorrhage and its maternal and perinatal outcome at a tertiary care hospital

Background: Antepartum haemorrhages are defined as bleeding from or into the genital tract after the period of viability untill delivery of the fetus. APH complicates 3-5% of pregnancies and is a leading cause of perinatal and maternal mortality worldwide. Objective of this study is to quantitate maternal morbidity, mortality and perinatal outcome in patients with APH at a tertiary care hospital.Methods: A retrospective observational study was carried out in the department of obstetrics and gynecology, Smt. Kashibai Navale medical college and general hospital, Pune. Patient information was obtained from the delivery records of 2018, 2019 and 2020. Patients presenting after the gestational age of 28 weeks with antepartum haemorrhage were included in the study.Results: Out of 100 cases of APH, abruptio placenta contributes to 60%, placenta previa to 37% and 3 cases were due to unknown cause. Overall maternal mortality was 3% and perinatal mortality was 23% in abruptio placentas compared to 13% in cases with placenta previa. Main cause of perinatal mortality was prematurity69%.Conclusions: Antepartum haemorrhage is one of the leading cause of perinatal mortality and morbidity. These cases should be deliverd at a centre with transfusion facility, NICU facility and by the obstetrician skilled in controlling intraoperative haemorrhage by stepwise devascularising sutures. Timely decision of uterine tamponade can also save few ceaserean hysterectomies

Can oral iron tablets be replaced by the intravenous iron sucrose in antenatal period? A new thought.

Background: Anaemia is the commonest medical disorder that contributes significantly to maternal morbidity and mortality, preterm delivery, intrauterine growth restriction. Pregnant women are particularly vulnerable to anaemia because they have dual iron requirements both for their growth and growth of foetus. A high proportion of women in both industrialized and developing countries become anaemic during pregnancy. Intravenous iron therapy is safe convenient and effective than oral iron therapy in prevention of iron deficiency anaemia when compliance is the problem. The aim of this study is to compare the efficacy, safety and acceptability of intravenous iron Vs oral iron in prevention of iron deficiency anaemia during pregnancy. The objective of the present research was to study the efficacy, safety and acceptability of oral iron (ferrous fumarate) versus intravenous iron (iron sucrose) for the prevention of iron deficiency anaemia during pregnancy.Methods: It was a prospective comparative case control study without blinding including 400 registered antenatal women in SKNMC and GH, Narhe, Pune. Results were based on collection and analysis of data from samples within study population.Results: There was no significant difference in mean haemoglobin rise between oral group and IV group but there is significant difference between mean ferritin levels between oral group and IV group. In IV group ferritin levels at 36 weeks were almost 1.8 times more than oral group. Acceptability and convenience of IV iron was significantly more than oral iron.Conclusions: Intravenous iron therapy in the form of three divided doses, one in each trimester can be safely used in the antenatal woman as an alternative to prophylactic iron tablets for prevention of iron deficiency anaemia especially in women who are non-compliant or does not tolerate oral iron tablets

A study of different contraceptive methods: need of the hour during COVID 19 pandemic

Background: COVID-19 disease is the pandemic caused by a single-stranded RNA virus that belongs to the coronavirus family known as 2019-nCoV (SARS-Co V). The disease is highly contagious and transmitted mainly by droplets or close contact. In this time of pandemic it is need of the hour to prevent more and more unwanted pregnancies. This study was to evaluate the contraceptive methods of choice which are easily available, cost effective and suitable to most of the patients during this terrible period of pandemic.Methods: This was a prospective observational study done from April 2020 to December 2020. Women coming to the OPD for contraceptive advice after medical termination of pregnancy and patients desiring postpartum contraception were included in the study. All data were collected from the OPD and IPD of our hospital. Different contraceptive methods available, their costs, hospital visits, complications, failure rate and reason for its discontinuation was analysed.Results: In this study 76.5% patients (n-459) accepted Inj. DMPA as compared to 10 % used Cu T and 13% used OC pills as a method of contraception. Inj DMPA is easily available, cost effective, has lesser side effects and need less hospital visits.Conclusions: DMPA should be made available as a first line method to all those who wishes to opt for reversible method of contraception. This study concludes, during the period of pandemic Inj DMPA was most preferred method of contraception