Hépatite virale B en République Démocratique du Congo : aspects génotypiques, sociologiques et effets de la vaccination chez les nouveau-nés du Kivu

The Democratic Republic of Congo (DRC) is still facing numerous challenges to control hepatitis B infection. The present thesis has targeted several useful levels of action for the characterization of the profile of hepatitis B infection as well as for the optimization of preventive policies. The estimated seroprevalence rate seems to classify the DRC among countries of intermediate endemicity with a different genotypic viral profile found in the Eastern and the Western part, respectively. To hope to eradicate this virus, the DRC must extend the immunization coverage. Although slightly low, the rate of vaccine response is acceptable and ranged within many African rates. At the same time, efforts are needed to improve the level of health-care workers knowledge toward hepatitis B.(MED - Sciences médicales) -- UCL, 201