Transflective liquid crystal display using separate transmissive and reflective liquid crystal cells and materials with single cell gap

A transflective liquid crystal display (TLCD) using separate transmissive (T) and reflective (R) cells in which two liquid crystal materials with different birefringence changes are used. The birefringence change of the R region is half of the birefringence change of the T region. In this case, a single cell gap is possible and identical transmittance and reflectance for R and T is obtained. It is applicable to various reflective LC modes, and the fabrication methods are simple

Transflective LCD Using Multilayer Dielectric Film Transflector

A novel transflective liquid crystal display (LCD) is provided with a multilayer dielectric film transflector. The dielectric transflector is composed of alternating high and low refractive index dielectric material layers deposited directly on the inner side of the LCD substrate to avoid parallax. The transmittance of the dielectric transflector can vary from approximately 5% to approximately 95% by simply adjusting the individual dielectric layer thickness and the arrangement of layers. The thickness of the 10-layer film is approximately 700 nm, which does not affect the voltage drop on the LC. Two structures of the dielectric film using different positions of the materials of construction are provided and demonstrated. Such a transflective LCD exhibits outstanding features, such as, robust dielectric film, single cell gap, no parallax, and a simple fabrication process

Perdeuterated cyanobiphenyl liquid crystals for infrared applications

Perdeuterated 4'-pentyl-4-cyanobiphenyl (D5CB) was synthesized and its physical properties evaluated and compared to those of 5CB. D5CB retains physical properties similar to those of 5CB, such as phase transition temperatures, dielectric constants, and refractive indices. An outstanding feature of D5CB is that it exhibits a much cleaner and reduced infrared absorption. Perdeuteration, therefore, extends the usable range of liquid crystals to the mid infrared by significantly reducing the absorption in the near infrared, which is essential for telecom applications

Cathode ray tube addressed liquid crystal light valve projection display

Integrating an epitaxially grown monocrystalline garnet cathode ray tube\u27s (CRT\u27s) high resolution and a liquid crystal light valve\u27s (LCLV\u27s) large screen and high brightness, we develop a CRT optically addressed LCLV projection display system. The CRT\u27s phosphor screen is green chrome yttrium aluminum garnet (Cr:YAG) fabricated by liquid phase epitaxy. The LCLV\u27s fabrication and the optical system\u27s design are given. The projection display system shows good performances

The discovery of potential acetylcholinesterase inhibitors: A combination of pharmacophore modeling, virtual screening, and molecular docking studies

<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease (AD) is the most common cause of dementia characterized by progressive cognitive impairment in the elderly people. The most dramatic abnormalities are those of the cholinergic system. Acetylcholinesterase (AChE) plays a key role in the regulation of the cholinergic system, and hence, inhibition of AChE has emerged as one of the most promising strategies for the treatment of AD.</p> <p>Methods</p> <p>In this study, we suggest a workflow for the identification and prioritization of potential compounds targeted against AChE. In order to elucidate the essential structural features for AChE, three-dimensional pharmacophore models were constructed using Discovery Studio 2.5.5 (DS 2.5.5) program based on a set of known AChE inhibitors.</p> <p>Results</p> <p>The best five-features pharmacophore model, which includes one hydrogen bond donor and four hydrophobic features, was generated from a training set of 62 compounds that yielded a correlation coefficient of R = 0.851 and a high prediction of fit values for a set of 26 test molecules with a correlation of R²= 0.830. Our pharmacophore model also has a high Güner-Henry score and enrichment factor. Virtual screening performed on the NCI database obtained new inhibitors which have the potential to inhibit AChE and to protect neurons from Aβ toxicity. The hit compounds were subsequently subjected to molecular docking and evaluated by consensus scoring function, which resulted in 9 compounds with high pharmacophore fit values and predicted biological activity scores. These compounds showed interactions with important residues at the active site.</p> <p>Conclusions</p> <p>The information gained from this study may assist in the discovery of potential AChE inhibitors that are highly selective for its dual binding sites.</p

First Identification of a Patient Colonized With Klebsiella pneumoniae Carrying blaNDM-1 in Taiwan

New Delhi metallo-β-lactamase 1 (NDM-1) is a novel type of metallo-β-lactamase (MBL). Enterobacteriaceae carrying this NDM-1 encoding gene, blaNDM-1, have been identified worldwide. Bacteria carrying blaNDM-1 are not only resistant to carbapenem, but also highly resistant to many classes of antibiotics, which indicate the importance of prompt identification of these bacteria and implementation of strict infection control measures to prevent their transmission. Here, we report the first identification and management of a patient colonized with Klebsiella pneumoniae carrying blaNDM-1 in Taiwan, who returned from New Delhi where he had been hospitalized for a gun-shot injury

Synthesis, formation and characterization of ZnTiO3 ceramics,Ceram

Abstract Zinc titanate (ZnTiO 3 ) powders of perovskite structure were synthesized by conventional solid state reaction using metal oxides. Powders of ZnO and TiO 2 in a molar ratio of 1:1 were mixed in a ball mill and then heated at temperatures from 700 to 1000 • C for various time periods in air. The crystallization temperature of ZnTiO 3 powder was ∼820 • C, activation energy for crystallization was ∼327.14 kJ/mol and for grain growth was ∼48.84 kJ/mol. A transition point was observed when the electrical resistivity was measured versus temperature. Like some ferroelectric materials, a PTCR behavior above the transition temperature was observed with Curie temperature of ∼5 • C