3,021 research outputs found
Numeral Quantifiers: NP Modifiers and Relational Quantity Nominals
Numeral quantifiers composed of the number and the classifier can either precede or follow nouns in Korean. This paper examines these prenominal and postnominal numeral quantifier constructions and argues that they have different structures. I propose that the numeral quantifier is an NP modifier of type , > in the prenominal quantifier construction, while it is a relational quantity nominal of type > taking the associated DP as its argument and forcing a monotonic interpretation in the postnominal quantifier construction. This analysis provides an account for a number of properties of numeral quantifier constructions that appear to be problematic for an alternative approach using movement which is perhaps most familiar way of dealing with prenominal and postnominal quantifier constructions
Medial Meniscal Tears in Anterior Cruciate Ligament-Deficient Knees: Effects of Posterior Tibial Slope on Medial Meniscal Tear
PURPOSE: To evaluate the incidence of meniscal tears in patients with chronic anterior cruciate ligament (ACL)-deficient knees, and to determine the influence of posterior tibial slope (PTS) on medial meniscal tears in ACL-deficient knees. MATERIALS AND METHODS: We reviewed 174 patients (174 knees) with a mean age of 30.7 years who underwent ACL reconstruction for chronic ACL tears. We divided the patients into two groups: low group (135 knees with a PTS or =13degrees). RESULTS: The incidence of medial meniscus tears was 44% (77/174), and that of lateral meniscus tears was 35% (61/174). The mean PTS in patients with medial meniscal tears was 11.4degrees+/-3.0degrees, whereas that in patients without medial meniscal tears was 9.8degrees+/-2.4degrees. The incidence of meniscal tears was 57.8% (78/135) in the low group and 89.7% (35/39) in the high group (p or =13degrees is a risk factor for secondary medial meniscal tears in ACL-deficient knees. So, we suggest that PTS is one of the considerations for determining early ACL reconstruction to prevent secondary meniscal tears.ope
The post-traumatic colour change of primary incisors: a colourimetric and longitudinal study
Background. Tooth colour change after trauma has been described subjectively as ranging from yellow/pink to grey/black.
Aim. To investigate the longitudinal colourimetric change of post-traumatic discoloured primary incisor using an intraoral colourimeter.
Design. A total of 34 primary incisors from 15 boys and eight girls were studied. The mean post-injury day during clinic visits (SD) and number of visit was 205.4 (194.8) and 3.9 (2.0). CIE L* (lightness), a* (green-red) and b* (blue-yellow) of the maxillary primary incisors were measured at every visit. The colour difference (ΔE*(ab)) was calculated between the traumatized tooth and the control. Scatter graphs were made depicting the colour change of discoloured teeth and the ΔE*(ab) over time.
Results. Mean CIE L*, a* and b* of the unaffected control were 80.8 (2.29), 0.9 (0.77) and 13.1 (2.67), respectively. L* gradually decreased to 70.7 (on day 71), then slowly recovered. a* increased to 3.7 (day 29) and decreased slowly. b* only demonstrated a small change that was within the control range during the follow-up. ΔE*(ab) increased to 9.58 (day 56) and decreased slowly.
Conclusion. The earlier recovery of a* was followed by the recovery of L*. During the post-traumatic period, ΔE*(ab) failed to reach the clinically acceptable threshold.OAIID:RECH_ACHV_DSTSH_NO:T201604270RECH_ACHV_FG:RR00200001ADJUST_YN:EMP_ID:A080446CITE_RATE:1.303FILENAME:Hyun_et_al-2016-International_Journal_of_Paediatric_Dentistry.pdfDEPT_NM:치의학과EMAIL:[email protected]_YN:YFILEURL:https://srnd.snu.ac.kr/eXrepEIR/fws/file/c834cd27-d2b1-499b-a99a-6be06246d6c3/linkCONFIRM:
Identification of protein functions using a machine-learning approach based on sequence-derived properties
<p>Abstract</p> <p>Background</p> <p>Predicting the function of an unknown protein is an essential goal in bioinformatics. Sequence similarity-based approaches are widely used for function prediction; however, they are often inadequate in the absence of similar sequences or when the sequence similarity among known protein sequences is statistically weak. This study aimed to develop an accurate prediction method for identifying protein function, irrespective of sequence and structural similarities.</p> <p>Results</p> <p>A highly accurate prediction method capable of identifying protein function, based solely on protein sequence properties, is described. This method analyses and identifies specific features of the protein sequence that are highly correlated with certain protein functions and determines the combination of protein sequence features that best characterises protein function. Thirty-three features that represent subtle differences in local regions and full regions of the protein sequences were introduced. On the basis of 484 features extracted solely from the protein sequence, models were built to predict the functions of 11 different proteins from a broad range of cellular components, molecular functions, and biological processes. The accuracy of protein function prediction using random forests with feature selection ranged from 94.23% to 100%. The local sequence information was found to have a broad range of applicability in predicting protein function.</p> <p>Conclusion</p> <p>We present an accurate prediction method using a machine-learning approach based solely on protein sequence properties. The primary contribution of this paper is to propose new <it>PNPRD </it>features representing global and/or local differences in sequences, based on positively and/or negatively charged residues, to assist in predicting protein function. In addition, we identified a compact and useful feature subset for predicting the function of various proteins. Our results indicate that sequence-based classifiers can provide good results among a broad range of proteins, that the proposed features are useful in predicting several functions, and that the combination of our and traditional features may support the creation of a discriminative feature set for specific protein functions.</p
Influence of Polypyrrole on Phosphorus- and TiO2-Based Anode Nanomaterials for Li-Ion Batteries
Phosphorus (P) and TiO2 have been extensively studied as anode materials for lithium-ion batteries (LIBs) due to their high specific capacities. However, P is limited by low electrical conductivity and significant volume changes during charge and discharge cycles, while TiO2 is hindered by low electrical conductivity and slow Li-ion diffusion. To address these issues, we synthesized organic–inorganic hybrid anode materials of P–polypyrrole (PPy) and TiO2–PPy, through in situ polymerization of pyrrole monomer in the presence of the nanoscale inorganic materials. These hybrid anode materials showed higher cycling stability and capacity compared to pure P and TiO2. The enhancements are attributed to the electrical conductivity and flexibility of PPy polymers, which improve the conductivity of the anode materials and effectively buffer volume changes to sustain structural integrity during the charge and discharge processes. Additionally, PPy can undergo polymerization to form multi-component composites for anode materials. In this study, we successfully synthesized a ternary composite anode material, P–TiO2–PPy, achieving a capacity of up to 1763 mAh/g over 1000 cycles
Determinants of gastric cancer screening attendance in Korea: a multi-level analysis
This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly credited.Abstract
Background
We aimed to assess individual and area-level determinants of gastric cancer screening participation.
Method
Data on gastric cancer screening and individual-level characteristics were obtained from the 2007–2009 Fourth Korea National Health and Nutrition Examination Survey. The area-level variables were collected from the 2005 National Population Census, 2008 Korea Medical Association, and 2010 National Health Insurance Corporation. The data were analyzed using multilevel logistic regression models.
Results
The estimated participation rate in gastric cancer screening adhered to the Korea National Cancer Screening Program guidelines was 44.0% among 10,658 individuals aged over 40 years who were included in the analysis. Among the individual-level variables, the highest income quartile, a college or higher education level, living with spouse, having a private health insurance, limited general activity, previous history of gastric or duodenal ulcer, and not currently smoking were associated with a higher participation rate in gastric cancer screening. Urbanization showed a significant negative association with gastric cancer screening attendance among the area-level factors (odds ratio (OR) = 0.73; 95% confidence interval (CI) = 0.57-0.93 for the most urbanized quartile vs. least urbanized quartile).
Conclusion
There are differences in gastric cancer screening attendance according to both individual and regional area characteristics
Ecologic correlation Study on Nutrients/Foods Intake and Mortal ity for Female Breast Cancer in Korea
In order to investigate the possible role of dieta-ry factors on the
recent increase in mortality for female breast cancer in Korea, an ecologic
correlation study between per capita intakes of nutrients and foods and the
mortality for female breast cancer during the last 10 years was conducted. In
spite of the possibility of an ecologic fallacy, the age-adjusted mortality rates for
female breast cancer were positively correlated with protein from animal source,
total lipid, total animal foods, animal foods to total intake, fresh fish and
shellfish, milk and milk products, and meat and meat products. The rates were
inversely associated with energy from cereal, total carbohydrate, vegetable foods
to total intake, total vegetable foods, daily intake of cereals and grain products,
and starch and starch roots. These results suggest that an increased intake of
protein- and fat-rich foods rather than carbohydrate-rich foods or vegetables
might be associated with the increase in mortality for breast cancer during the
last 10 years in Korea
Association of Polymorphisms in Browzine Journal Cover Fshr, inha, Esr1, and Bmp15 With Recurrent Implantation Failure
Recurrent implantation failure (RIF) refers to two or more unsuccessful in vitro fertilization embryo transfers in the same individual. Embryonic characteristics, immunological factors, and coagulation factors are known to be the causes of RIF. Genetic factors have also been reported to be involved in the occurrence of RIF, and some single nucleotide polymorphisms (SNPs) may contribute to RIF. We examined SNPs i
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Secular changes in dental development of Korean children aged 4 to 16 years over a 10-year period
This study evaluated 10-year secular changes in dental maturity and dental development among Korean children. A retrospective analysis of panoramic radiograph samples from Korean children (4–16 years old) taken in 2010 and 2020 was conducted. The 2010 group consisted of 3491 radiographs (1970 boys and 1521 girls), and the 2020 group included 5133 radiographs (2825 boys and 2308 girls). Using Demirjian’s method, dental maturity scores and dental developmental stages were assessed. For intra-observer reliability, Weighted Cohen’s kappa was used, and Mann-Whitney U tests were performed to compare the 2020 and 2010 groups. A slight acceleration in dental maturity was observed in both boys and girls, with the difference being more noticeable in boys at an earlier age. Statistically significant differences were noted at ages 4, 5 and 7 for boys, and at age 6 for girls. Despite these differences, the individual dental development stages of 2020 and 2010 showed inconsistent trends with limited differences. Generally, girls demonstrate more advanced dental maturity than boys. A slight acceleration in Korean children’s dental maturity was observed over a 10-year period when comparing the 2020 groups to the 2010 groups
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