13 research outputs found
Frequency Domain-based Dataset Distillation
This paper presents FreD, a novel parameterization method for dataset
distillation, which utilizes the frequency domain to distill a small-sized
synthetic dataset from a large-sized original dataset. Unlike conventional
approaches that focus on the spatial domain, FreD employs frequency-based
transforms to optimize the frequency representations of each data instance. By
leveraging the concentration of spatial domain information on specific
frequency components, FreD intelligently selects a subset of frequency
dimensions for optimization, leading to a significant reduction in the required
budget for synthesizing an instance. Through the selection of frequency
dimensions based on the explained variance, FreD demonstrates both theoretical
and empirical evidence of its ability to operate efficiently within a limited
budget, while better preserving the information of the original dataset
compared to conventional parameterization methods. Furthermore, based on the
orthogonal compatibility of FreD with existing methods, we confirm that FreD
consistently improves the performances of existing distillation methods over
the evaluation scenarios with different benchmark datasets. We release the code
at https://github.com/sdh0818/FreD.Comment: Accepted at NeurIPS 202
Phage-Based Biocontrol of Antibiotic-Resistant Bacterium Isolated from Livestock Wastewater Treatment Plant
The presence of antibiotic-resistant bacteria (ARB) in receiving water can severely threaten the aquatic environment and human health. The treated effluent containing ARB in some livestock wastewater treatment plants (WWTPs) is returned to the municipal WWTP to reduce the residual ammonia and phosphorus concentrations. ARBs are widespread through wastewater treatment processes and are discharged into river and lake. This study highlights that the isolated lytic phage could reduce ARB isolated from livestock WWTPs and apply phage-based biocontrol in mixed cultures. ARB and lytic phages were isolated from livestock wastewater and used in a batch reactor with diverse cultures. The isolated bacterium was from the Aeromonas species and was resistant to various antibiotics (penicillin, tetracycline, colistin, and kanamycin), indicating multi-drug resistance and biofilm formation. The isolated lytic phage successfully infected Aeromonas species in pure culture and was relatively stable in terms of pH, temperature, and toxic chemicals. The multiplicity of infection (MOI) was examined to determine the proper phage number to kill the host bacterium. The optimal number to control the isolated ARB was a 1:100 phage-to-host ratio. Scanning electron microscopy showed that lytic phages reduced bacterial growth and biofilm formation. Phage-mediated biocontrol was applied in a batch reactor with mixed cultures. Pyrosequencing data from the batch reactor indicated that lytic phages reduced the proportion of the isolated ARB from 65.7 to 20% in 24 h. This study provides evidence for the possible application of lytic phages to control ARB in treated wastewater and an alternative method to prevent the widespread exposure of ARB without producing chemical byproducts
Mapping of lymphosomes in the canine forelimb : comparative anatomy between canines and humans
Background: Breast cancerārelated lymphedema is an unsolved iatrogenic dilemma. Disfigurement of the affected limb because of increased volume and recurrent cellulitis can cause both physical and mental distress for many breast cancer survivors. No adequate animal models have been developed to investigate acquired lymphedema mimicking breast cancerārelated lymphedema, and there is little knowledge of the anatomy of the lymphatics in animals. The authors hypothesized that a canine forelimb model of the lymphatic system could potentially be used to study breast cancerārelated lymphedema. Methods: Six forequarters were used from three mongrel hound carcasses. The lymphatic microinjection technique used hydrogen peroxide to identify lymphatic vessels. The individual channels were injected with a radiopaque lead oxide mixture and recorded on digital radiography. Lymphatic territories (lymphosomes) in the canine forelimb were demarcated and color coded in accordance with their lymph nodes. The lymphatic system in the canine forelimb was compared with that in the human upper extremity. Results: The lymphatic system in the canine forelimb was divided into two superficial lymphosomes (ventral cervical and axillary) and one deep lymphatic system. The ventral cervical lymphosome was larger than the axillary lymphosome. A single lymph node in the axilla received fluid from three sites: the ventral cranial torso, the superficial medial forelimb, and the deep forelimb. The lymphatic systems of the human upper extremity and the canine forelimb had some anatomical similarities: distinct superficial and deep system and size of the lymphatic vessel. Conclusion: The canine model may be a valuable animal model for investigating the pathophysiology of upper extremity lymphedema.9 page(s
Prediction of Mortality after Burn Surgery in Critically Ill Burn Patients Using Machine Learning Models
Severe burns may lead to a series of pathophysiological processes that result in death. Machine learning models that demonstrate prognostic performance can be used to build analytical models to predict postoperative mortality. This study aimed to identify machine learning models with the best diagnostic performance for predicting mortality in critically ill burn patients after burn surgery, and then compare them. Clinically important features for predicting mortality in patients after burn surgery were selected using a random forest (RF) regressor. The area under the receiver operating characteristic curve (AUC) and classifier accuracy were evaluated to compare the predictive accuracy of different machine learning algorithms, including RF, adaptive boosting, decision tree, linear support vector machine, and logistic regression. A total of 731 patients met the inclusion and exclusion criteria. The 90-day mortality of the critically ill burn patients after burn surgery was 27.1% (198/731). RF showed the highest AUC (0.922, 95% confidence interval = 0.902–0.942) among the models, with sensitivity and specificity of 66.2% and 93.8%, respectively. The most significant predictors for mortality after burn surgery as per machine learning models were total body surface area burned, red cell distribution width, and age. The RF algorithm showed the best performance for predicting mortality
Unusual Na+ ion intercalation/deintercalation in metal-rich Cu1.8S for Na-ion batteries
A key issue with Na-ion batteries is the development of active materials with stable electrochemical reversibility through the understanding of their sodium storage mechanisms. We report a sodium storage mechanism and properties of a new anode material, digenite Cu1.8S, based on its crystallographic study. It is revealed that copper sulfides (CuxS) can have metal-rich formulas (x ā„ 1.6), due to the unique oxidation state of +1 found in group 11 elements. These phases enable the unit cell to consist of all strong CuāS bonds and no direct SāS bonds, which are vulnerable to external stress/strain that could result in bond cleavage as well as decomposition. Because of its structural rigidness, the Cu1.8S shows an intercalation/deintercalation reaction mechanism even in a low potential window of 0.1ā2.2 V versus Na/Na+ without irreversible phase transformation, which most of the metal sulfides experience through a conversion reaction mechanism. It uptakes, on average, 1.4 Na+ ions per unit cell (ā¼250 mAh gā1) and exhibits ā¼100% retention over 1000 cycles at 2C in a tuned voltage range of 0.5ā2.2 V through an overall solid solution reaction with negligible phase separation
LiCl-LiI molten salt electrolyte with bismuth-lead positive electrode for liquid metal battery
Liquid metal batteries (LMBs) are attractive energy storage device for large-scale energy storage system (ESS) due to the simple cell configuration and their high rate capability. The high operation temperature caused by high melting temperature of both the molten salt electrolyte and metal electrodes can induce the critical issues related to the maintenance cost and degradation of electrochemical properties resulting from the thermal corrosion of materials. Here, we report a new chemistry of LiCl-LiI electrolyte and Bi-Pb positive electrode to lower the operation temperature of Li-based LMBs and achieve the long-term stability. The cell (Li vertical bar LiCl-LiI vertical bar Bi-Pb) is operated at 410 degrees C by employing the LiCl-LiI (LiCl:LiI = 36:64 mol %) electrolyte and Bi-Pb alloy (Bi:Pb = 55.5:44.5 mol %) positive electrode. The cell shows excellent capacity retention (86.5%) and high Coulombic efficiencies over 99.3% at a high current density of 52 mA cm(-2) during 1000th cycles
Autogenous fat grafting for mild-to-moderate postoperative temporal hollowing after decompressive craniectomy: One-year follow-up
Background Temporal hollowing is inevitable after decompressive craniectomy. This complication affects self-perception and quality of life, and various techniques and materials have therefore been used to restore patientsā confidence. Autologous fat grafting in postoperative scar tissue has been considered challenging because of the hostile tissue environment. However, in this study, we demonstrate that autologous fat grafting can be a simple and safe treatment of choice, even for postoperative depressed temporal scar tissue. Methods Autologous fat grafting was performed in 13 patients from 2011 to 2016. Fat was harvested according to Colemanās strategy, using a tumescent technique. Patient-reported outcomes were collected preoperatively and at 1-month and 1-year follow-ups. Photographs were taken at each visit. Results The thighs were the donor site in all cases for the first procedure. The median final volume of harvested fat was 29.4 mL (interquartile range [IQR], 24.0ā32.8 mL). The median final volume of fat transferred into the temporal area was 4.9 mL on the right side (IQR, 2.5ā7.1 mL) and 4.6 mL on the left side (IQR, 3.7ā5.9 mL). There were no major complications. The patient-reported outcomes showed significantly improved self-perceptions at 1 month and at 1 year. Conclusions Despite concerns about the survival of grafted fat in scar tissue, we advise autologous fat grafting for patients with temporal hollowing resulting from a previous craniectomy
Hygroscopic Behavior of Polypropylene Nanocomposites Filled with Graphene Functionalized by Alkylated Chains
Owing to stringent international environmental and fuel efficiency requirements for lightweight automotive systems, polymer composites have attracted widespread attention. Polypropylene (PP) is a widely employed commercial polymer because of its lightweight and low cost. In this study, PP nanocomposites were fabricated to reduce the moisture absorption of PP composites in automotive headlamp housings. Alkylated chemically modified graphene (CMG-R) was synthesized to reduce the surface hydrophilicity of graphene and increase compatibility with the PP matrix. Fourier transform-infrared spectroscopy and scanning electron microscopy were performed to analyze the nanofillers. X-ray diffraction was performed to determine the interlayer spacing of the nanofiller resulting from surface treatment. Differential scanning calorimetry was used to analyze the crystallinity of the nanocomposites. The results indicated that the improved hydrophobicity of the nanofiller due to alkylation reduced the maximum moisture absorption of the PP nanocomposites by 15% compared to PP composites. The findings of this study are useful for reducing fogging in automotive headlamps
Tribological Properties of Polyamide 46/Graphene Nanocomposites
Polyamide 46 (PA46) is used in various automotive parts because of its excellent heat resistance and mechanical properties. This study aims to improve the frictional properties of PA46 using the lubricating ability of graphene. Nanocomposites are prepared via two mixing methods: Graphene powder is compounded directly with PA46 pellets through a twin-screw extruder, or PA46 powder is added to graphene dispersion for self-adsorption, and subsequently, it is dried and compounded with PA46 through the twin-screw extruder. Application of the nanocomposite in the friction field is evaluated via the pin-on-disk method. The coefficient of friction of the nanocomposite prepared by self-adsorption is lower than that of the nanocomposite prepared by direct compounding. The mechanical properties of the nanocomposite fabricated by self-adsorption are superior to those of other materials. This can be attributed to the uniform dispersion of graphene and the strong attractive force between the PA46 matrix and graphene