PLANNING OF FLEXIBLE TRANSPORT SERVICES FOR RURAL AREA CONSIDERING OPERATION COST

This paper focuses on the potential role of Flexible Transport Service (FTS) in low and dispersed demand area. In Japan, after the deregulation in 2002, some mass transit companies left from bus services in local areas. This causes problems to some older people and disabled people with difficulties on traveling in rural areas. To meet these needs, the term demand responsive transit (DRT) has been increasingly applied because it can provide passengers with alternative options on route, schedule, at a lower operating cost compared to the infrequent fixed route local public bus services. DRT needs, however, a quite large subsidy for the low density area and is not so popular for elderly people because of it’s level of service. On the other hand, Taxi Subsidy Scheme (TSS) that subsidizes on the taxi fare is being carried out widely by local authorities in Japan to support the special groups’ transport needs. In this research, we aimed to examine the role of taxi subsidy system from the relation with on demand ride-sharing taxi in depopulated area

Stock Market Reaction to Announcement of Goodwill Impairment

松尾聿正教授 退職記念

A Beneficial Role of Rooibos in Diabetes Mellitus: A Systematic Review and Meta-Analysis

In a rapid increase in cases of diabetes mellitus worldwide, there has been interested in the use of plant-derived polyphenols as nutraceuticals to prevent the onset and progression of diabetes mellitus and its associated complications. Aspalathus linearis, commonly known as rooibos, is a rich source of uncommon glycosylated plant polyphenols with various critical health-promoting properties, including the prevention and treatment of diabetes mellitus (DM). This study aimed to examine these effects by meta-analyzing the current evidence in diabetic rodent models. Peer-reviewed studies written in English from two databases, PubMed and Embase, were searched up to 28 February 2018. Studies reporting blood glucose levels in diabetic rodents with and without receiving rooibos extracts or their major phenolic compounds are included. Twelve studies enrolling 88 diabetic rodents treated with rooibos extracts or their polyphenols and 85 diabetic control males reported blood glucose levels. The pooled effect size was −0.89 (95% CI: −1.44 to −0.35) with a substantial heterogeneity (I2 = 67.0%). This effect was likely to be modified by type of rooibos extracts and their polyphenols and treatment period. Blood glucose levels were significantly lower in diabetic rodent models treated with the phenolic compound rich in rooibos extracts, PPAG

がん細胞特異的なWarburg効果を標的とした新たな制がん戦略

東京理科大学201