Management of angle-closure glaucoma secondary to spherophakia: A report and brief review of treatment options

A 16-year-old girl presenting with chronic headaches had findings of high myopia, uniformly shallow anterior chambers, and spherical crystalline lenses in both eyes with elevated intraocular pressure (IOP) in the left eye. The optic discs were healthy and axial lengths were normal. Antiglaucoma medications were initiated. Inadvertent cycloplegia paradoxically aided control of pressures within 24 h. On review, gonioscopy revealed nonsynechial angle closure. Dilatation revealed no zonulodialysis or subluxation bilaterally. The edge of the lens was clearly seen. A diagnosis of bilateral spherophakia with secondary angle-closure glaucoma in the left eye was made. She underwent sequential phacoemulsification with foldable intraocular lens implantation which adequately controlled her IOPs. Identifying spherophakia when presented with high myopia, raised IOPs and shallow anterior chambers, and documenting peripheral synechiae, subluxation, and zonular weakness may prove crucial in the management of secondary angle-closure glaucoma in such cases

A rare variant of ankyloblepharon filiforme adnatum associated with skin hypopigmentation: A case report from South India

We report ankyloblepharon filiforme adnatum (AFA) along with associated skin lesions in a 7-day-old child from South India. It could be a variant of the well described ankyloblepharon-ectodermal defects-cleft lip and palate syndrome also called Hay–Wells syndrome wherein AFA, skin lesions, and clefting are characteristic. The ocular features, genetic inheritance, and possible systemic associations, along with the options for management, are discussed. The need for awareness among ophthalmologists of its systemic associations is discussed to ensure that proper multidisciplinary care is offered to the individuals affected by this rare disorder. This article also highlights the unusual hypopigmented skin lesions found in this infant, which has been scantily reported in the literature, as a possible variation in patients of Indian ethnicity