Ancient Schwannoma-A rare case

Schwannoma is a relatively uncommon, slow-growing benign tumor that is derived apparently from the Schwann cells lining the nerve sheath. The schwannoma is usually a solitary lesion, and can be multiple when associated with neurofibromatosis. A case of 40-year-old women with a swelling in her mid-portion of the lower lip is presented. The diagnosis was established based on clinical, histopathological, and immunohistochemical aspects. Keywords: Benign tumor, neural tumors, oral lesions, Schwann cells, schwannoma, soft tissue tumorsEthiopian Journal of Health Sciences vol 22 (3) 201

Niosomes as vesicular carriers for delivery of proteins and biologicals

Over the past several years, treatment of infectious diseases and immunization has undergone a paradigm shift. Stemming from the nanobiotechnology research, not only a large number of disease-specific biologicals have been developed, but also enormous efforts have been made to effectively deliver these biologicals. Niosomes are vesicular systems prepared from self-assembly of hydrated non-ionic surfactants. Opinions of the usefulness of niosomes in delivery of proteins and biologicals range from unsubstantiated optimism to undeserved pessimism. This article reviews the current deepening and widening of interest of niosomes in many scientific disciplines, and their application in medicine particularly for the delivery of proteins (insulin, cyclosporine, bacitracin, trypsin), vaccines and antigens (bovine serum albumin, antigen tetanus toxoid, haemagglutinin). This article also presents an overview of techniques of noisome preparation, characterization of niosomes and their applications.Keywords: Niosomes, Proteins, Biologicals, Vaccines, Oral deliver

Niosomes as vesicular carriers for delivery of proteins and biologicals

Over the past several years, treatment of infectious diseases and immunization has undergone a paradigm shift. Stemming from the nanobiotechnology research, not only a large number of disease-specific biologicals have been developed, but also enormous efforts have been made to effectively deliver these biologicals. Niosomes are vesicular systems prepared from self-assembly of hydrated non-ionic surfactants. Opinions of the usefulness of niosomes in delivery of proteins and biologicals range from unsubstantiated optimism to undeserved pessimism. This article reviews the current deepening and widening of interest of niosomes in many scientific disciplines, and their application in medicine particularly for the delivery of proteins (insulin, cyclosporine, bacitracin, trypsin), vaccines and antigens (bovine serum albumin, antigen tetanus toxoid, haemagglutinin). This article also presents an overview of techniques of noisome preparation, characterization of niosomes and their applications.Keywords: Niosomes, Proteins, Biologicals, Vaccines, Oral deliver

Effect of Progressive Gaze Stability Exercises on Holistic Aspects of Chronic Motion Sensitivity

Background: Motion sensitivity, also referred to as motion sickness, is a common condition among general population. It is a complex syndrome and is associated with presence of nausea and vomiting headache, drowsiness, cold sweating, pallor of varying degrees, increased salivation. Postural instability and anxiety are also identified to be associated with motion sensitivity. There is a close relationship between the vestibular system and motion sensitivity and vestibular system. The aim of this study was to investigate the effect of progressive gaze stability exercises on holistic aspects of chronic motion sensitivity. Methods: A single blind randomized controlled trial was conducted where participants were blinded to type of intervention. Forty one healthy young adults of both genders within the age group of 20 to 40 years with chronic motion sensitivity were recruited in the study. Baseline and post intervention assessment of postural stability, motion sensitivity, and anxiety was measured for each participant using, Bertec Balance Advantage-Dynamic Computerized Dynamic Posturography with Immersion Virtual Reality (CDP-IVR), Motion Sensitivity Quotient (MSQ), Motion Sensitivity Susceptibility Questionnaire Short Form (MSSQ-Short), and State-Trait Anxiety Inventory for Adults (STAI Form Y-2). Results: There was a significant difference for condition 2 (p=0.05), but not for condition 1 (p=0.44) for the mean CDP-IVR average score post intervention between the intervention and sham groups. For condition 2, the intervention group had 117% increase in CDP-IVR average score compared to 35.2% increase in the sham group. Also, there was a significant difference in mean MSQ between the two groups (p=0.045). There was a significant inverse correlation between MSQ and CDP-IVR average equilibrium % of Condition 1 (ρ = -0.44, p = 0.004). Conclusions: Progressive gaze stability exercises reduced motion sensitivity and improved postural stability in participants with chronic motion sensitivity. Also, perception of motion sensitivity was observed to be inversely correlated with postural stability. There was no impact of gaze stability exercises observed on subjective perception of anxiety among this population. Also, HEP adherence strategies were beneficial to ensure exercise adherence in participants with chronic motion sensitivity

A uterus didelphys with breech presentation in a previously scarred uterus; an incidental finding

A didelphic uterus results from failed fusion of the paired mullerian ducts characterized by two separated uterine horns, each with an endometrial cavity and uterine cervix. Pregnancies develop in one of the two horns, and of the major uterine malformations, the didelphys uterus has the best reproductive prognosis. Improved fetal survival may be secondary to earlier diagnosis, which favors earlier and more intensive prenatal care. Pregnancy is associated with an increased risk of malpresentations and premature labor, although many patients will have no reproductive difficulties. We report a case of successful pregnancy outcome in our institute in a case of didelphys uterus by Caesarean section

Multiagent autonomous energy management

The objective of this thesis is to design distributed software agents for reliable operation of integrated electric power systems of modern electric warships. The automatic reconfiguration of electric shipboard power systems is an important step toward improved fight-through and self-healing capabilities of naval warships. The improvements are conceptualized by redesigning the electric power system and its controls. This research focuses on a new scheme for an energy management system in the form of distributed control/software agents. Multiagent systems provide an ideal level of abstraction for modeling complex applications where distributed and heterogeneous entities need to cooperate to achieve a common goal. The agents\u27 task is to ensure supply of the various load demands while taking into consideration system constraints and load and supply path priorities. A self-stabilizing maximum flow algorithm is investigated to allow implementation of the agents\u27 strategies and find a global solution by only considering local information and a minimum amount of communication. (Abstract shortened by UMI.)

Testing the multipole structure and conservative dynamics of compact binaries using gravitational wave observations: The spinning case

In an earlier work [S. Kastha et al., PRD {\bf 98}, 124033 (2018)], we developed the {\it parametrized multipolar gravitational wave phasing formula} to test general relativity, for the non-spinning compact binaries in quasi-circular orbit. In this paper, we extend the method and include the important effect of spins in the inspiral dynamics. Furthermore, we consider parametric scaling of PN coefficients of the conserved energy for the compact binary, resulting in the parametrized phasing formula for non-precessing spinning compact binaries in quasi-circular orbit. We also compute the projected accuracies with which the second and third generation ground-based gravitational wave detector networks as well as the planned space-based detector LISA will be able to measure the multipole deformation parameters and the binding energy parameters. Based on different source configurations, we find that a network of third-generation detectors would have comparable ability to that of LISA in constraining the conservative and dissipative dynamics of the compact binary systems. This parametrized multipolar waveform would be extremely useful not only in deriving the first upper limits on any deviations of the multipole and the binding energy coefficients from general relativity using the gravitational wave detections, but also for science case studies of next generation gravitational wave detectors.Comment: 16 pages, 8 figures, Mathematica readable supplemental material file for all the inputs to calculate the parametrized waveform is with the sourc

Multiparameter tests of general relativity using multiband gravitational-wave observations

In this Letter we show that multiband observations of stellar-mass binary black holes by the next generation of ground-based observatories (3G) and the space-based Laser Interferometer Space Antenna (LISA) would facilitate a comprehensive test of general relativity by simultaneously measuring all the post-Newtonian (PN) coefficients. Multiband observations would measure most of the known PN phasing coefficients to an accuracy below a few percent---two orders-of-magnitude better than the best bounds achievable from even `golden' binaries in the 3G or LISA bands. Such multiparameter bounds would play a pivotal role in constraining the parameter space of modified theories of gravity beyond general relativity.Comment: 7 pages, 4 figures. v3: version published in PR

Data Aware Routing in Wireless Sensor Networks

The wireless sensor network (WSN) has set of wireless intelligent sensor nodes with high speed network. Nodes are deployed randomly in a surge of unanticipated applications. The routing is one of the most important challenges in WSNs for data transmission over the sensor nodes. The paper proposes the data aware routing in WSNs, which incorporates energy efficient routing of data. The objective of the proposed work is to improve the performance of network in terms of energy consumption and throughput. The simulation results show that the proposed approach perform better in-terms of utilization of minimum energy, efficient for cluster formation, and reduce communication overhead in WSNs