Nonlinear dynamic characteristic of gear system with the eccentricity

In this paper, the dynamic behavior of a spur gear system was studied with external and internal dynamic incentive. The vibration differential equations for spur gear system were expressed in equivalent discrete models of mass, damping, and spring elements using the Lagrange equation considering the effect of lateral-torsional vibration coupling on the dynamics of gears, which was solved by the Newmark method. The investigation was carried out with multi-degree of freedom system for spur gear model, which took into account gravity, gear eccentricity, backlash, dynamic transmission error and external dynamic incentive. The lateral and torsional response characteristics of geared system were analyzed by changing the value of the rotational speed, backlash and eccentricity. It was shown from the research that the jump discontinuous phenomenon occurred at lower backlash value with increasing rotational speed and the frequency amplitudes also increased, and the regions of continuous frequency became winder when the rotational speed difference was greater. Moreover, complicated combination frequency components followed a rule of increasing firstly and then decreasing with the different backlash and eccentricity. The study may contribute to a further understanding of the dynamic characteristics of such a gear rotor-bearing system

Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice

Huntington's disease results from expansion of a glutamine repeat (>36 glutamines) in the N-terminal region of huntingtin (htt) and is characterized by preferential neurodegeneration in the striatum of the brain. N171-82Q mice that express N-terminal 171 amino acids of htt with an 82-glutamine repeat show severe neurological phenotypes and die early, suggesting that N-terminal mutant htt is pathogenic. In addition, various cellular factors and genetic modifiers are found to modulate the cytotoxicity of mutant htt. Understanding the contribution of these factors to HD pathogenesis will help identify therapeutics for this disease. To investigate the role of interleukin type 1 (IL-1), a cytokine that has been implicated in various neurological diseases, in HD neurological symptoms, we crossed N171-82Q mice to type I IL-1 receptor (IL-1RI) knockout mice. Mice lacking IL-1RI and expressing N171-82Q show more severe neurological symptoms than N171-82Q or IL-1RI knockout mice, suggesting that lack of IL-1RI can promote the neuronal toxicity of mutant htt. Lack of IL-1RI also increases the accumulation of transgenic mutant htt in the striatum in N171-82Q mice. Since IL-1RI signaling mediates both toxic and protective effects on neurons, its basal function and protective effects may be important for preventing the neuropathology seen in HD

An Image Encryption Scheme Based on DNA Computing and Cellular Automata

Networks have developed very quickly, allowing the speedy transfer of image information through Internet. However, the openness of these networks poses a serious threat to the security of image information. The field of image encryption has drawn attention for this reason. In this paper, the concepts of 1-dimensional DNA cellular automata and T-DNA cellular automata are defined, and the concept of reversible T-DNA cellular automata is introduced. An efficient approach to encryption involving reversible T-DNA cellular automata as an encryption tool and natural DNA sequences as the main keys is here proposed. The results of a simulation experiment, performance analysis, and comparison to other encryption algorithms showed this algorithm to be capable of resisting brute force attacks, statistical attacks, and differential attacks. It also enlarged the key space enormously. It meets the criteria for one-time pad and resolves the problem that one-time pad is difficult to save