Small-sized magnetolevitation system of the trestle type for the Arctic

The construction of large technical systems (industrial and transport) poses a threat to the environmental situation in the Arctic. On the other hand, the operation of such systems in harsh Arctic conditions is also unsafe, especially in permafrost conditions. We offer a small-sized maglev system of the trestle type with “movers” and “fellow travelers” type suspension. In this system, the track magnetic field is created by a moving sequence of interacting magnetic field sources –movers in a special control channel (beam, pipe), which also interact with the magnetic field sources of transport modules –fellow travelers. Fellow travelers are suspended in controlled channels due to interaction with permanent sources of magnetic field. The structure is mounted on arc-shaped supports that evenly distribute the load on the supporting surface and protect it from snow drifts and water flows. A model of a two-channel system with the lower location of the controlled channel has been developed. Further improvement of the system involves the use of the “magnetic potential hole” effect and the principles of the planetary model construction

Small-sized magnetolevitation system of the trestle type for the Arctic

The construction of large technical systems (industrial and transport) poses a threat to the environmental situation in the Arctic. On the other hand, the operation of such systems in harsh Arctic conditions is also unsafe, especially in permafrost conditions. We offer a small-sized maglev system of the trestle type with “movers” and “fellow travelers” type suspension. In this system, the track magnetic field is created by a moving sequence of interacting magnetic field sources –movers in a special control channel (beam, pipe), which also interact with the magnetic field sources of transport modules –fellow travelers. Fellow travelers are suspended in controlled channels due to interaction with permanent sources of magnetic field. The structure is mounted on arc-shaped supports that evenly distribute the load on the supporting surface and protect it from snow drifts and water flows. A model of a two-channel system with the lower location of the controlled channel has been developed. Further improvement of the system involves the use of the “magnetic potential hole” effect and the principles of the planetary model construction

Aerodynamic numerical calculations of air-cooled condensers and dry cooling towers at different wind velocities and multilevel configuration of sections

Multilevel configuration of heat exchange sections of air-cooled condensers and dry cooling towers with a multi-row arrangement are offered. Results of a research of the combined operation of fans and V-shaped heat exchangers by methods of numerical model operation at wind and without it for three-row sections are given. It is shown that in the presence of wind multilevel configuration of heat exchange sections has advantages over single-level configuration

Aerodynamic numerical calculations of air-cooled condensers and dry cooling towers at different wind velocities and multilevel configuration of sections

Multilevel configuration of heat exchange sections of air-cooled condensers and dry cooling towers with a multi-row arrangement are offered. Results of a research of the combined operation of fans and V-shaped heat exchangers by methods of numerical model operation at wind and without it for three-row sections are given. It is shown that in the presence of wind multilevel configuration of heat exchange sections has advantages over single-level configuration

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation.

Integrin-mediated force application induces a conformational change in latent TGF-β1 that leads to the release of the active form of the growth factor from the extracellular matrix (ECM). Mechanical activation of TGF-β1 is currently understood as an acute process that depends on the contractile force of cells. However, we show that ECM remodeling, preceding the activation step, mechanically primes latent TGF-β1 akin to loading a mechanical spring. Cell-based assays and unique strain devices were used to produce a cell-derived ECM of controlled organization and prestrain. Mechanically conditioned ECM served as a substrate to measure the efficacy of TGF-β1 activation after cell contraction or direct force application using magnetic microbeads. The release of active TGF-β1 was always higher from prestrained ECM as compared with unorganized and/or relaxed ECM. The finding that ECM prestrain regulates the bioavailability of TGF-β1 is important to understand the context of diseases that involve excessive ECM remodeling, such as fibrosis or cancer