384 research outputs found

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    Formation of the Ring-like Structure in the SN 1987A Nebula due to the Magnetic Pressure of the Toroidal Field

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    Several weeks after the explosion of supernova (SN) 1987A, the UV flash of the SN illuminated a ring-like structure in the circumstellar material at about 0.65 ly from the SN. The interaction between the stellar winds from the SN progenitor is considered to be the candidate for the formation of the circumstellar structure. In the case that the stellar winds are spherically symmetric, the interaction should result in a shell-like structure. However, in this paper we show that the magnetic field in the winds causes an anisotropy which leads to the formation of a ring-like structure. When the fast wind of the blue supergiant phase of the progenitor sweeps up the surrounding slow wind of the red-supergiant phase, the magnetic field as well as the wind material are piled up in the interaction region. Since the magnetic energy increases in proportion to the square of the amplitude, the magnetic field exhibits its effect prominently at the interaction region; due to the magnetic pressure force the material at lower latitudes is compressed into a ring-like structure. It is suggested that this magnetic process can also explain the newly observed pair of rings of the SN 1987A nebula.Comment: 18 pages LaTeX, 3 PostScript figure

    Expression and intracellular localization of FKHRL1 in mammary gland neoplasms.

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    FKHRL1 (FOXO3a), a member of the Forkhead family of genes, has been considered to be involved in the development of breast tumors; however, the in vivo expression and activation status of FKHRL1 in breast tumors still remains unclear. We immunohistochemically demonstrated the expression and intracellular localization of FKHRL1 in human breast tumors by the novel anti-FKHRL1 antibody which is available for formalin-fixed paraffin-embedded specimens. In a total of 51 cases of benign tumors, FKHRL1 was diffusely expressed in all cases, and its intracellular localization was revealed to be cytoplasmic (inactive form) in 94% of cases of intraductal papillomas (16/17) and 91% cases of fibroadenomas (31/34), with a similar pattern to normal glandular epithelium. In invasive ductal carcinomas, 83% of the cases (93/112) diffusely expressed FKHRL1; however, unlike benign tumors, 71% of the cases (66/93) showed the nuclear-targeted, active form of FKHRL1. Moreover, activated FKHRL1 was predominantly observed in scirrhous (29/36, 81% of the cases) and papillotubular (30/38, 79% of the cases) subtypes, compared to the solid-tubular subtype (7/19, 37% of the cases). Furthermore, the cases with nuclear-targeted FKHRL1 showed a tendency to have lymph nodal metastasis with statistical significance (P < 0.0001). Thus, the activation of FKHRL1 seems to be recognized as one of the specific features of invasive ductal carcinoma of the breast.</p
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