714 research outputs found
Lorentz-Violating Running of Coupling Constants
We compute the full vacuum polarization tensor in the minimal QED extension.
We find that its low-energy limit is dominated by the radiatively induced
Chern-Simons-like term and the high-energy limit is dominated by the c-type
coefficients. We investigate the implications of the high-energy limit for the
QED and QCD running couplings. In particular, the QCD running offers the
possibility to study Lorentz-violating effects on the parton distribution
functions and observables such as the hadronic R ratio.Comment: Presented at the Eighth Meeting on CPT and Lorentz Symmetry,
Bloomington, Indiana, May 12-16, 201
Evidence for a change in the nuclear mass surface with the discovery of the most neutron-rich nuclei with 17<Z <25
The results of measurements of the production of neutron-rich nuclei by the
fragmentation of a 76-Ge beam are presented. The cross sections were measured
for a large range of nuclei including fifteen new isotopes that are the most
neutron-rich nuclides of the elements chlorine to manganese (50-Cl, 53-Ar,
55,56-K, 57,58-Ca, 59,60,61-Sc, 62,63-Ti, 65,66-V, 68-Cr, 70-Mn). The enhanced
cross sections of several new nuclei relative to a simple thermal evaporation
framework, previously shown to describe similar production cross sections,
indicates that nuclei in the region around 62-Ti might be more stable than
predicted by current mass models and could be an indication of a new island of
inversion similar to that centered on 31-Na.Comment: 4 pages, 3 figures, to be published in Physical Review Letters, 200
Production cross sections from 82Se fragmentation as indications of shell effects in neutron-rich isotopes close to the drip-line
Production cross sections for neutron-rich nuclei from the fragmentation of a
82Se beam at 139 MeV/u were measured. The longitudinal momentum distributions
of 126 neutron-rich isotopes of elements 11 <= Z <= 32 were scanned using an
experimental approach of varying the target thickness. Production cross
sections with beryllium and tungsten targets were determined for a large number
of nuclei including several isotopes first observed in this work. These are the
most neutron-rich nuclides of the elements 22 <= Z <= 25 (64Ti, 67V, 69Cr,
72Mn). One event was registered consistent with 70Cr, and another one with
75Fe. The production cross sections are correlated with Qg systematics to
reveal trends in the data. The results presented here confirm our previous
result from a similar measurement using a 76Ge beam, and can be explained with
a shell model that predicts a subshell closure at N = 34 around Z = 20. This is
demonstrated by systematic trends and calculations with the Abrasion-Ablation
model that are sensitive to separation energies.Comment: 13 pages, 11 figures, accepted to Phys.Rev.
Enhancing Interferon Regulatory Factor 7 Mediated Antiviral Responses and Decreasing Nuclear Factor Kappa B Expression Limit HIV-1 Replication in Cervical Tissues
Establishment of a productive HIV-1 infection in the female reproductive tract likely depends on the balance between anti-viral and pro-inflammatory responses leading to activation and proliferation of HIV target cells. Immune modulators that boost anti-viral and depress pro-inflammatory immune responses may decrease HIV-1 infection or replication. Polyinosinic: polycytidylic [Poly (I:C)] has been reported to down-regulate HIV-1 replication in immune cell subsets and lymphoid tissues, yet the scope and mechanisms of poly (I:C) regulation of HIV-1 replication in the cervicovaginal mucosa, the main portal of viral entry in women remain unknown. Using a relevant, underexplored ex vivo cervical tissue model, we demonstrated that poly (I:C) enhanced Interferon Regulatory Factor (IRF)7 mediated antiviral responses and decreased tissue Nuclear Factor Kappa B (NF κ B) RNA expression. This pattern of cellular transcription factor expression correlated with decreased HIV-1 transcription and viral release. Reducing IRF7 expression up-regulated HIV-1 and NFκB transcription, providing proof of concept for the critical involvement of IRF7 in cervical tissues. By combining poly (I:C) with a suboptimal concentration of tenofovir, the leading anti-HIV pro-phylactic microbicide candidate, we demonstrated an earlier and greater decrease in HIV replication in poly (I:C)/tenofovir treated tissues compared with tissues treated with tenofovir alone, indicating overall improved efficacy. Poly (I:C) decreases HIV-1 replication by stimulating IRF7 mediated antiviral responses while reducing NFκB expression. Early during the infection, poly (I:C) improved the anti-HIV-1 activity of suboptimal concentrations of tenofovir likely to be present during periods of poor adherence i.e. inconsistent or inadequate drug use. Understanding interactions between anti-viral and pro-inflammatory immune responses in the genital mucosa will provide crucial insights for the identification of targets that can be harnessed to develop preventative combination strategies to improve the efficacy of topical or systemic antiviral prophylactic agents and protect women from HIV-1 and other sexually transmitted infections
Production cross sections of neutron rich isotopes from a 82Se beam
Production cross sections for neutron-rich nuclei from the fragmentation of a
82Se beam at 139 MeV/u were measured. The longitudinal momentum distributions
of 122 neutron-rich isotopes of elements were determined by
varying the target thickness. Production cross sections with beryllium and
tungsten targets were determined for a large number of nuclei including several
isotopes first observed in this work. These are the most neutron-rich nuclides
of the elements (64Ti, 67V, 69Cr, 72Mn). One event was
registered consistent with 70Cr, and another one with 75Fe. A one-body Qg
systematics is used to describe the production cross sections based on thermal
evaporation from excited prefragments. The current results confirm those of our
previous experiment with a 76Ge beam: enhanced production cross sections for
neutron-rich fragments near Z=20.Comment: Talk given at the 11th International Conference on Nucleus-Nucleus
Collisions (NN2012), San Antonio, Texas, USA, May 27-June 1, 2012. To appear
in the NN2012 Proceedings in Journal of Physics: Conference Series (JPCS
S17(0) Determined from the Coulomb Breakup of 83 MeV/nucleon 8B
A kinematically complete measurement was made of the Coulomb dissociation of
8B nuclei on a Pb target at 83 MeV/nucleon. The cross section was measured at
low relative energies in order to infer the astrophysical S factor for the
7Be(p,gamma)8B reaction. A first-order perturbation theory analysis of the
reaction dynamics including E1, E2, and M1 transitions was employed to extract
the E1 strength relevant to neutrino-producing reactions in the solar interior.
By fitting the measured cross section from Erel = 130 keV to 400 keV, we find
S17(0) = 17.8 (+1.4, -1.2) eV b
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