Experiment Definition Using the Space Laboratory, Long Duration Exposure Facility, and Space Transportation System Shuttle

Candidate experiments designed for the space shuttle transportation system and the long duration exposure facility are summarized. The data format covers: experiment title, Experimenter, technical abstract, benefits/justification, technical discussion of experiment approach and objectives, related work and experience, experiment facts space properties used, environmental constraints, shielding requirements, if any, physical description, and sketch of major elements. Information was also included on experiment hardware, research required to develop experiment, special requirements, cost estimate, safety considerations, and interactions with spacecraft and other experiments

Mitral valve and left ventricular features in malignant mitral valve prolapse.

Objective: Mitral valve prolapse is a benign condition, however with occasional reports of sudden cardiac death or out-of-hospital cardiac arrest in the absence of severe mitral regurgitation or coronary artery disease, suggesting the existence of a malignant form. The objective of our study was to contribute to the characterisation of malignant mitral valve prolapse. Methods: We performed a retrospective analysis of pathology findings in 68 consecutive cases of sudden cardiac death with mitral valve prolapse as lone abnormal finding, reported as cause of death. Results: All mitral valve prolapse sudden death cases had mitral valve characteristics of Barlow disease, with extensive bileaflet multisegmental prolapse and dilatation of the annulus. The majority of cases (80.9%) had microscopic left ventricular fibrosis with associated hypertrophy and degenerative features of the myocytes, and some cases (10.9%) had right ventricular fibrosis as well. Conclusions: Malignant mitral valve prolapse is Barlow disease. Sudden cardiac death in mitral valve prolapse is due to Barlow disease, which besides the typical mitral valve degeneration may comprise a distinct Barlow disease cardiomyopathy, as suggested by myocyte degeneration and bi-ventricular involvement

Material flow during the extrusion of simple and complex cross-sections using FEM

This paper deals with the extrusion of rod and shape sections and uses a 3D finite element model analysis (FEM) to predict the effect of die geometry on maximum extrusion load. A description of material flow in the container is considered in more detail for rod and shape sections in order to fully comprehend the transient conditions occurring during the process cycle. A comparison with experiments is made to assess the relative importance of some extrusion parameters in the extrusion process and to ensure that the numerical discretisation yields a realistic simulation of the process. The usefulness and the limitation of FEM are discussed when modelling complex shapes. Results are presented for velocity contours and shear stress distribution during the extrusion process. It is shown that for most of the shapes investigated, the material making up the extrudate cross-sections originates from differing regions of virgin material within the billet. The outside surface of the extrudate originates from the material moving along the dead metal zone (DMZ) and the core of the extrudate from the central deformation zone. The FE program appears to predict all the major characteristics of the flow observed macroscopically

Material flow during the extrusion of simple and complex cross-sections using FEM

This paper deals with the extrusion of rod and shape sections and uses a 3D finite element model analysis (FEM) to predict the effect of die geometry on maximum extrusion load. A description of material flow in the container is considered in more detail for rod and shape sections in order to fully comprehend the transient conditions occurring during the process cycle. A comparison with experiments is made to assess the relative importance of some extrusion parameters in the extrusion process and to ensure that the numerical discretisation yields a realistic simulation of the process. The usefulness and the limitation of FEM are discussed when modelling complex shapes. Results are presented for velocity contours and shear stress distribution during the extrusion process. It is shown that for most of the shapes investigated, the material making up the extrudate cross-sections originates from differing regions of virgin material within the billet. The outside surface of the extrudate originates from the material moving along the dead metal zone (DMZ) and the core of the extrudate from the central deformation zone. The FE program appears to predict all the major characteristics of the flow observed macroscopically

Variation of turbulent burning rate of methane, methanol, and iso-octane air mixtures with equivalence ratio at elevated pressure

Turbulent burning velocities for premixed methane, methanol, and iso-octane/air mixtures have been experimentally determined for an rms turbulent velocity of 2 m/s and pressure of 0.5 MPa for a wide range of equivalence ratios. Turbulent burning velocity data were derived using high-speed schlieren photography and transient pressure recording; measurements were processed to yield a turbulent mass rate burning velocity, utr. The consistency between the values derived using the two techniques, for all fuels for both fuel-lean and fuel-rich mixtures, was good. Laminar burning measurements were made at the same pressure, temperature, and equivalence ratios as the turbulent cases and laminar burning velocities and Markstein numbers were determined. The equivalence ratio (φ) for peak turbulent burning velocity proved not always coincident with that for laminar burning velocity for the same fuel; for isooctane, the turbulent burning velocity unexpectedly remained high over the range φ = 1 to 2. The ratio of turbulent to laminar burning velocity proved remarkably high for very rich iso-octane/air and lean methane/air mixtures

Inter-Personal and Critical-Thinking Capabilities in Those about to Enter Qualified Social Work: A Six-Centre Study

The ‘process’ of intervention is understood to be fundamental to social work—evident in, for example, the literature on reflexivity. Little work, though, has focused on the detailed excavation of the cognitive processes of reasoning in decision making. This is widely recognised as requiring considerable analytic and critical abilities. Although this is long established, its importance is contemporarily apparent at the policy level from the rationale underlying current initiatives such as Frontline. However, it is also long understood that the reasoning capabilities underlying these processes cannot be considered in isolation from the inter-personal–emotional, encapsulated in a long-term theoretical concern for both Heart and Head. Furthermore, terms like ‘capability’ or ‘proficiency’ in professional qualification imply some standard to be reached in practice. This invites measurement. This novel study seeks to bring together three dimensions of the (i) measurement of (ii) the inter-personal–emotional and (iii) critical thinking—measurement of key facets of both Head and Heart. A six-centre, six-university collaboration, it focuses on those at a crucial point: where individuals are about to enter qualified practice. The findings show they score highly on most inter-personal measures (with room for improvement), but show huge variability in critical-thinking capabilities. The implications of this are discussed

Detecting the harmonics of oscillations with time-variable frequencies

A method is introduced for the spectral analysis of complex noisy signals containing several frequency components. It enables components that are independent to be distinguished from the harmonics of nonsinusoidal oscillatory processes of lower frequency. The method is based on mutual information and surrogate testing combined with the wavelet transform, and it is applicable to relatively short time series containing frequencies that are time variable. Where the fundamental frequency and harmonics of a process can be identified, the characteristic shape of the corresponding oscillation can be determined, enabling adaptive filtering to remove other components and nonoscillatory noise from the signal. Thus the total bandwidth of the signal can be correctly partitioned and the power associated with each component then can be quantified more accurately. The method is first demonstrated on numerical examples. It is then used to identify the higher harmonics of oscillations in human skin blood flow, both spontaneous and associated with periodic iontophoresis of a vasodilatory agent. The method should be equally relevant to all situations where signals of comparable complexity are encountered, including applications in astrophysics, engineering, and electrical circuits, as well as in other areas of physiology and biology

Vortex -- Kink Interaction and Capillary Waves in a Vector Superfluid

Interaction of a vortex in a circularly polarized superfluid component of a 2d complex vector field with the phase boundary between superfluid phases with opposite signs of polarization leads to a resonant excitation of a ``capillary'' wave on the boundary. This leads to energy losses by the vortex--image pair that has to cause its eventual annihilation.Comment: LaTeX 7 pages, no figure