Genetic Polymorphisms in Caveolin-1 Associate with Breast Cancer Risk in Chinese Han Population

Caveolin-1(CAV-1) was demonstrated to be a tumor suppressor gene and be implicated in the development of breast cancer (BC). Numerous potentially functional polymorphisms in CAV-1 have been identified, but their effects on BC were not clear. This case-control study aims to evaluate the relationship between CAV-1 polymorphisms and BC risk. 560 BC patients and 583 healthy controls were enrolled in the present study, all from Chinese Han population. We detected 3 single nucleotide polymorphisms (rs3807987, rs1997623, and rs7804372) in CAV-1 using the Sequenom MassARRAY method. The association between CAV-1genotypes and BC risk was assessed in six genetic models by calculating the odds ratio (OR) and 95% confidence intervals (95% CIs) with χ2-test. The CAV-1rs3807987 polymorphism was observed to increase the risk of BC And the A allele of rs3807987 relates to a larger tumor size (≥2cm) and lower incidence of PR-positive BC while the AA genotype of rs7804372 associates with a higher ER and Her-2 positive rate among BC patients. In addition, Ars1997623Grs3807987Trs7804372 haplotype was linked to a decreased risk of BC (OR =0.64, 95%CI=0.44-0.93), whereas Crs1997623Ars3807987Trs7804372 haplotype was related to an increased BC risk (OR =1.74, 95%CI=1.04-2.92). Our study suggests that CAV-1 rs3807987 can increase the BC risk among Chinese Han women. And the rs3807987 and rs7804372 in CAV-1 may serve as predictors for prognosis of BC

Bursts of terahertz radiation from large-scale plasmas irradiated by relativistic picosecond laser pulses

Powerful terahertz (THz) radiation is observed from large-scale underdense preplasmas in front of a solid target irradiated obliquely with picosecond relativistic intense laser pulses. The radiation covers an extremely broad spectrum with about 70% of its energy located in the high frequency regime over 10 THz. The pulse energy of the radiation is found to be above 100  μJ per steradian in the laser specular direction at an optimal preplasma scale length around 40–50  μm. Particle-in-cell simulations indicate that the radiation is mainly produced by linear mode conversion from electron plasma waves, which are excited successively via stimulated Raman scattering instability and self-modulated laser wakefields during the laser propagation in the preplasma. This radiation can be used not only as a powerful source for applications, but also as a unique diagnostic of parametric instabilities of laser propagation in plasmas

Measurement of the chi_{c2} Polarization in psi(2S) to gamma chi_{c2}

The polarization of the chi_{c2} produced in psi(2S) decays into gamma chi_{c2} is measured using a sample of 14*10^6 psi(2S) events collected by BESII at the BEPC. A fit to the chi_{c2} production and decay angular distributions in psi(2S) to gamma chi_{c2}, chi_{c2} to pi pi and KK yields values x=A_1/A_0=2.08+/-0.44 and y=A_2/A_0=3.03 +/-0.66, with a correlation rho=0.92 between them, where A_{0,1,2} are the chi_{c2} helicity amplitudes. The measurement agrees with a pure E1 transition, and M2 and E3 contributions do not differ significantly from zero.Comment: 6 pages, 4 figures, 1 tabl

Measurement of the branching fractions of psi(2S) -> 3(pi+pi-) and J/psi -> 2(pi+pi-)

Using data samples collected at sqrt(s) = 3.686GeV and 3.650GeV by the BESII detector at the BEPC, the branching fraction of psi(2S) -> 3(pi+pi-) is measured to be [4.83 +- 0.38(stat) +- 0.69(syst)] x 10^-4, and the relative branching fraction of J/psi -> 2(pi+pi-) to that of J/psi -> mu+mu- is measured to be [5.86 +- 0.19(stat) +- 0.39(syst)]% via psi(2S) -> (pi+pi-)J/psi, J/psi -> 2(pi+pi-). The electromagnetic form factor of 3(pi+pi-) is determined to be 0.21 +- 0.02 and 0.20 +- 0.01 at sqrt(s) = 3.686GeV and 3.650GeV, respectively.Comment: 17pages, 7 figures, submitted to Phys. Rev.

Measurements of J/psi decays into phi pi^0, phi eta, and phi eta^prime

Based on 5.8x10^7 J/psi events detected in BESII, the branching fractions of J/psi--> phi eta and phi eta^prime are measured for different eta and eta^prime decay modes. The results are significantly higher than previous measurements. An upper limit on B(J/psi--> phi pi^0) is also obtained.Comment: 9 pages, 10 figure

Observation of p pbar pi^0 and p pbar eta in psi' decays

The processes psi'-->p pbar pi^0 and psi'-->p pbar eta are studied using a sample of 14 million psi' decays collected with the Beijing Spectrometer at the Beijing Electron-Positron Collider. The branching fraction of psi'-->p pbar pi^0 is measured with improved precision as (13.2\pm 1.0\pm 1.5)\times 10^{-5}, and psi'-->p pbar eta is observed for the first time with a branching fraction of (5.8\pm 1.1\pm 0.7)\times 10^{-5}, where the first errors are statistical and the second ones are systematic.Comment: 15 pages, 8 figures and 3 table

Search for psi(3770)\ra\rho\pi at the BESII detector at the Beijing Electron-Positron Collider

Non-$D\bar{D}$ decay \psppto \rhopi is searched for using a data sample of $(17.3\pm 0.5) pb^{-1}$ taken at the center-of-mass energy of 3.773 GeV by the BESII detector at the BEPC. No \rhopi signal is observed, and the upper limit of the cross section is measured to be \sigma(\EETO \rhopi)<6.0 pb at 90% C. L. Considering the interference between the continuum amplitude and the \pspp resonance amplitude, the branching fraction of \pspp decays to $\rho\pi$ is determined to be \BR(\pspp\ra\rho\pi)\in(6.0\times10^{-6}, 2.4\times10^{-3}) at 90% C. L. This is in agreement with the prediction of the $S$- and $D$-wave mixing scheme of the charmonium states for solving the ``\rhopi puzzle'' between \jpsi and \psp decays.Comment: 15 pages, 5 figure

Measurements of ψ(2S)\psi(2S) decays into Vector- Tensor final states

Decays of the $\psi(2S)$ into vector plus tensor meson final states have been studied with 14 million $\psi(2S)$ events collected with the BESII detector. Branching fractions of \psi(2S) \rt \omega f_{2}(1270), $\rho a_2(1320)$, $K^*(892)^0\bar{K}^*_2(1430)^0+c.c.$ and $\phi f_2^{\prime}(1525)$ are determined. They improve upon previous BESI results and confirm the violation of the "12%" rule for $\psi(2S)$ decays to VT channels with higher precision.Comment: 7 pages, 7 figures and 2 table

Measurements of the continuum RudsR_{\rm uds} and RR values in e+e−e^+e^- annihilation in the energy region between 3.650 and 3.872 GeV

We report measurents of the continuum $R_{\rm uds}$ near the center-of-mass energy of 3.70 GeV, the $R_{{\rm uds(c)}+\psi(3770)}(s)$ and the $R_{\rm had}(s)$ values in $e^+e^-$ annihilation at 68 energy points in the energy region between 3.650 and 3.872 GeV with the BES-II detector at the BEPC Collodier. We obtain the $R_{\rm uds}$ for the continuum light hadron (containing u, d and s quarks) production near the $D\bar D$ threshold to be $R_{\rm uds}=2.141 \pm 0.025 \pm 0.085$.Comment: 5 pages, 3 figure

Measurement of the final states ωπ0\omega \pi^0, ρη\rho \eta, and ρη′\rho \eta^{'} from \psip electromagnetic decays and \ee annihilations

Cross sections and form factors for \ee \to \wpi, $\rho\eta$, and \rho\etap at center of mass energies of 3.650, 3.686, and 3.773 GeV are measured using data samples collected with the BESII detector at the BEPC. Also, the branching fractions of \psi(2S) \rar \wpi, $\rho\eta$, and \rho\etap are determined to be $(1.87^{+0.68}_{-0.62}\pm0.28)\times 10^{-5}$, $(1.78^{+0.67}_{-0.62}\pm0.17)\times 10^{-5}$, and $(1.87^{+1.64}_{-1.11}\pm0.33)\times10^{-5}$, respectively.Comment: 8 pages, 4 figures, 4 table