First Report of the Multidrug Resistance Gene cfr in Enterococcus faecalis of Animal Origin

The multiresistance gene cfr was identified for the first time in an Enterococcus faecalis isolate of animal origin. The 32,388-bp plasmid pEF-01, which carried the cfr gene, was sequenced completely. Three copies of the insertion sequence IS1216 were identified in pEF-01, and the detection of a cfr- and IS1216-containing amplicon by inverse PCR suggests that IS1216 may play a role in the dissemination of cfr by a recombination process

First Report of the Multidrug Resistance Gene cfr in Enterococcus faecalis of Animal Origin

The multiresistance gene cfr was identified for the first time in an Enterococcus faecalis isolate of animal origin. The 32,388-bp plasmid pEF-01, which carried the cfr gene, was sequenced completely. Three copies of the insertion sequence IS1216 were identified in pEF-01, and the detection of a cfr- and IS1216-containing amplicon by inverse PCR suggests that IS1216 may play a role in the dissemination of cfr by a recombination process.This is article published as Liu, Yang, Yang Wang, Congming Wu, Zhangqi Shen, Stefan Schwarz, Xiang-Dang Du, Lei Dai, Wanjiang Zhang, Qijing Zhang, and Jianzhong Shen. "First report of the multidrug resistance gene cfr in Enterococcus faecalis of animal origin." Antimicrobial agents and chemotherapy 56, no. 3 (2012): 1650-1654. doi: 10.1128/AAC.06091-11. Posted with permission.</p