R.M. Schindler y la reintegración radical del espacio interior y exterior

California del Sur, muy alejada de las tradiciones y los duros climas del norte de Europa y del Este de los Estados Unidos se convirtió en un campo de pruebas ideal para diseños donde la vida en el exterior era tan importante como la vida en el interior. Uno de los pioneros de esta arquitectura fue R. M. Schindler (1887-1953), que llegó a Los Ángeles en diciembre de 1920 y que vivió y trabajó en California del Sur hasta su muerte. Schindler produjo una obra, tanto escritos como edificios, de una originalidad sorprendente, que pasó mayoritariamente desapercibida durante su vida pero que ahora deberíamos reconocer por su relevancia en el desarrollo de la arquitectura del siglo XX

(Re)pensando a atuação docente no ensino de Geografia nos anos iniciais do ensino fundamental

This work aims and analyze pedagogical practices in the teaching of Geography in the initial years of Elementary Education, highlighting the resources that favor meaningful learning. It is necessary to point out that this initial phase is in the literacy process, where the priority is reading and writing. Given this, it is essential to discover how Geography can contribute to the acquisition of this knowledge. It also aims at the importance of the teacher as mediator and director of more dynamic classes, using new tools that help the student to better understand the world in which it is inserted. The basis for this work was made through a bibliographical survey of authors and academic papers that discuss strategies that assist in the teaching / learning process. Part of the process of this work is a research done with 10 (ten) teachers from the initial years of the municipal public network. In this sense, search for elements that allow the understanding of this scenario, regarding new educational paradigms, a field that has the scope of the study of wanting to learn / want to do / want to change and launches reflection on didactics as a tool to improve the educational process.Este trabalho tem por objetivo de analisar as práticas pedagógicas no ensino de Geografia nos anos iniciais do Ensino Fundamental, ressaltando os recursos que favorecem para uma aprendizagem significativa. É necessário salientar que essa fase inicial se encontra no processo de alfabetização, no qual a prioridade consiste na leitura e na escrita. Diante disso, é primordial descobrir como a Geografia pode contribuir para aquisição desse conhecimento. Visa também à importância do professor como mediador e realizador de aulas mais dinâmicas, utilizando de novas ferramentas que auxiliam o aluno a uma melhor compreensão do mundo no qual está inserido. A fundamentação para a realização deste trabalho foi feita através de um levantamento bibliográfico de autores e trabalhos acadêmicos que abordam estratégias que auxiliam no processo de ensino/aprendizagem. Faz parte do processo deste trabalho uma pesquisa realizada com 10 (dez) professores dos anos iniciais da rede pública municipal. Neste sentido, busca elementos que permitam a compreensão deste cenário, no que tange a novos paradigmas educacionais, campo que tem por escopo o estudo do querer aprender/querer fazer/querer mudar e lança a reflexão sobre a didática como ferramenta para melhoria do processo educacional

Molecular cloning and characterization of human endothelial nitric oxide synthase

AbstractThe constitutive calcium/calmodulin-dependent nitric oxide (NO) synthase expressed in vascular endothelium shares common biochemical and pharmacologic properties with neuronal NO synthase. However, recent cloning and molecular characterization of NO synthase from bovine endothelial cells indicated the existence of a family of constitutive NO synthases. Accordingly, we undertook molecular cloning and sequence analysis of human endothelial NO synthase. Complementary DNA clones predict a protein of 1,203 amino acids sharing 94% identity with the bovine endothelial protein, but only 60% identity with the rat brain NO synthase isoform. Northern blot analysis with an endothelial-derived cDNA identified a 4.6–4.8 kb mRNA transcript in HUVEC and in situ hybridization localized transcripts to vascular endothelium but not neuronal tissue

Differences in interproximal and occlusal tooth wear among prehistoric tennessee indians: Implications for masticatory function

Breadth of the interproximal wear facet between lower P2 and M1 and between lower M1 and M2 was measured in human skeletal samples representing the Archaic, Woodland, and Mississippian periods of Tennessee River Valley prehistory, with the aim of assessing relative magnitudes of applied masticatory forces. When stratified by level of occlusal wear, mean interproximal facet breadth was consistently larger in the Archaic sample than in the Mississippian sample, with the Woodland sample intermediate. An analysis of covariance demonstrated that there was significant (p < 0.01) differences in facet size among the three groups even when differences in crown breadth were taken into account. Similar results were obtained in regressions of facet size on chronological age (Archaic larger than Mississippian at p < 0.01). Since rate of occlusal wear appears to be somewhat greater in the Archaic sample than in the later samples, the differences in interproximal wear are probably underestimated. It is suggested that the high levels of interproximal wear in the Archaic are indicative of the large occlusal forces and repetitive chewing required to masticate a diet of seeds, wild plant foods, and small animals, for which prior preparation (e.g., grinding, cooking) was minimal or nonexistent (as indicated by paleofecal samples). The lower amounts of interproximal wear observed in the Woodland and Mississippian samples imply considerable reductions in strenuous mastication, perhaps due to the widespread adoption during these periods of pottery and the earth oven, together with ethnographically-documented techniques of food preparation that transformed most foods to a soft consistency.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/37612/1/1330570111_ftp.pd

Phallogaster saccatus

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Elaphomyces granulatus

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Camarops petersii

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Phallogaster saccatus

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Volvariella bombycina

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