RELATIONSHIP BETWEEN HELICOBACTER PYLORI IMMUNOGLOBULIN G ANTIBODY AND THROMBOTIC ISCHEMIC STROKE

"nSeveral studies have assessed association between Helicobacter pylori infection and thrombotic ischemic stroke. This study was designed to investigate the association between this organism and ischemic strokes. Antibody against H. pylori (Hp IgG) was measured in 81 patients with stroke and 43 subjects without stroke. Hp IgG titer more than 20u/ml was defined as positive. 67.4% of control subjects and 70.4% of cases were Hp IgG seropositive (P = 0.838). The means of serum Hp IgG titers in control subjects and cases were 51.1859 u/ml and 50.1641 u/ml, respectively (P = 0.927). The difference between these 2 groups was not significant statistically. There wasn't any significant difference in seropositivity of Hp IgG between case and control subjects in men and women. H. pylori IgG titer hasn't a predictive role for thrombotic ischemic stroke

A Comparative Study about Effectiveness of an Exercise therapy Program on Improvement of gait and Balance in Left and Right Hemiplegia

Abstract Introduction: Impairment in the function of the brain caused by deficiency in the brain circulation is called stroke. Stroke is the most important factor of disability in adults. One of the most prevalent consequences of stroke is disability of walking or so-called (gait disorder) so that more than 50 percent of the patients who are in the acute phase of the disease are not capable of walking, and need to a rehabilitation period to reach for walking. Methods: In order to compare the effect of exercise therapy on the function of walking and balance and Improvement of depression in left and right hemiplegics patients, a Non-randomized clinical study was done. This study consisted of 13 right- hemiplegics patients with an average age of (60.46 ± 1.47) and 13 left hemiplegics patients with an average age of (61.92 ± 2.01) who were matched in age, height and weight. To measure the function of walking the Gait Dynamic Index, function of balance the Berg Balance Scale and Depression Beck Depression Questionnaire were used.The data were analyzed by SPSS software. To compare the effect of exercise therapy on the improvement of walking and balance before and after the treatment in each group t-paired -test and for more comparison of the two groups an independent T-test was used. Results: With analyzing the received data the following results were derived: From the viewpoint of walking, a significant difference in the right hemiplegics group (

Iranian consensus on use of vitamin D in patients with multiple sclerosis

Background: Accumulating evidences from experimental, epidemiologic and clinical studies support the potential linkage between poor vitamin D status and the risk of developing Multiple Sclerosis (MS), as well as, an adverse disease course. However, the results of the trials on the clinical outcomes of vitamin D supplementation in MS patients are less consistent which brought many discrepancies in routine practice. In this article we presented a summary of a symposium on vitamin D and MS. In this symposium we aim to review the current data about the relationship between vitamin D and MS, and suggest management guides for practicing neurologists. Discussion: Generally, supplementation seems to be reasonable for all MS and clinically isolated syndrome (Rinaldi et al., Toxins 7:129-37, 2015) patients with serum 25(OH)D level below 40ng/ml. In patients with vitamin D insufficiency or deficiency, a large replacing dose (e.g. 50,000IU capsules of D per week for 8-12 week) is recommended. Panel also suggested: the checking of the serum vitamin D, and calcium level, as well as, patients' compliance after the initial phase; a maintenance treatment of 1500-2000IU daily or equivalent intermittent (weekly, biweekly or monthly) Dose, considering the patient's compliance; routine check of serum vitamin D level at least two times a year especially at the beginning of spring and autumn; Serum vitamin D evaluation for first degree relatives of MS patients at high risk age and supplementation in case of insufficiency (25(OH)D less than 40 ng/ml); correction of vitamin D deficiency and insufficiency before pregnancy, as well as, a daily dose of 1500-2000IU or equivalent biweekly intake in 2nd and 3rd trimesters; stopping supplementation if 25(OH)D serum level exceeds 100ng/ml. Summary: Although the results of high power studies are not available, correcting vitamin D status seems plausible in all MS and CIS patients. Maintaining the serum 25(OH)D level between 40 and 100 ng/ml is not known to exert adverse effect. More ever, it might be associated with lower disease activity. © 2016 Jahromi et al