IMPACTS OF DIFFERENT CONCENTRATIONS OF AQUEOUS GREEN TEA EXTRACT ADMINISTERED DURING METHOTREXATE TREATMENT ON SOME SELECTED BLOOD INDICES IN RATS

Objective: This study was designed to investigate the impacts of administering of different concentrations of Aqueous Green Tea Extract (AGTE) (0.625, 1.25 or 2.5%) during Methotrexate (MTX) treatment, and continued for 5 days, on blood indices in rats. Methods: Six groups of white Albino rats were utilized:  Group I- (Control, received water); Group II- [single i. p. injection (20 mg/kg) of MTX], Group III- [1.25% concentration of AGTE alone for 5 days], and Groups IV, V and VI- [rats were administered, respectively AGTE (0.625, 1.25 or 2.5%), during MTX treatment, and continued for 5 days]. Results: The results showed that MTX alone induced significant decreases in Hb, HCT, MCHC, MCH, RBCs, and total WBCs; while, it increased platelets count. Administration of different concentrations of AGTE during MTX produced significant decrease in total WBCs and platelets;  while significant increase in Hb, HCT, MCHC, MCH;  meanwhile, significant increase, or decrease, respectively in MCV (depending on the concentration of AGTE); and a significant increase in RBCs only was seen at 2.5% AGTE plus MTX), compared to MTX-treated animals. Conclusion: Marked alterations in blood indices were obtained from this study when AGTE was administered during MTX treatment. So this study recommends taking into account such administration when MTX is therapeutically utilized

Characterization of mouse major urinary protein genes

Major urinary protein (MUP) genes were isolated from C57 genomic libraries, characterized by restriction enzyme mapping and compared with MUP genes isolated from BALB/c genomic libraries (Clark et al, 1982; Bishop et al, 1982). The conclusions drawn from the characterization of this new set of MUP genes are in agreement with those previously drawn from studies on the BALB/c MUP genes.Most MUP genes were found to share extensive homology in their transcription units and 5' and 3' flanking regions. Exceptions were those genes whose coding regions have been interupted by insertions and/or deletions. The MUP genes fall into two main groups based on hybridization criteria: group 1 and group 2 (Bishop et al, 1982). With the exception of one group 2 gene (BL-25/CL-2), restriction site homology was found to be greater within groups than between than. Restriction site homologies further divided the group 1 genes into two sub-groups. Sequence data revealed that the two sub-groups have different forms of an A-rich region located M0bp upstream of the TATA box.Messenger RNA from tissues that express MUP was shown to be more homologous to group 1 coding sequences than to group 2 coding sequences. In the liver, two forms of MUP mRNA can be distinguished. Group 1 sequences hybridized preferentially to the abundantly transcribed long form of the mRNA, while group 2 sequences hybridized preferentially to the short and rarer form of the mRNA. Genomic digests illustrated that two types of variation are found between the MUP genes of BALB/c and C57BL/Fa mice. The first relates to the presence of variant restriction fragments. Two cloned MUP genes carrying such fragments were identified. The second relates to variation in the intensity of common restriction fragments. Differences between the strains in the total number of MUP genes were not observed. Variation in the intensity of common restriction fragments are proposed to be the result of different homogenization events that took place in the mouse lineages from which BALB/c and C57BL/Fa were derived

Semantic and organization considerations in database conceptual modelling : the Semantic Conceptual Organizational Model (SECOM)

This thesis presents a new approach to designing large organizational databases. The approach emphasizes the need for a holistic approach to the design process. The development of the proposed approach was based on a comprehensive examination of the issues of relevance to the design and utilization of databases. Such issues include conceptual modelling, organization theory, and semantic theory. The conceptual modelling approach presented in this thesis is developed over three design stages, or model perspectives. In the semantic perspective, concept definitions were developed based on established semantic principles. Such definitions rely on meaning - provided by intension and extension - to determine intrinsic conceptual definitions. A tool, called meaning-based classification (MBC), is devised to classify concepts based on meaning. Concept classes are then integrated using concept definitions and a set of semantic relations which rely on concept content and form. In the application perspective, relationships are semantically defined according to the application environment. Relationship definitions include explicit relationship properties and constraints. The organization perspective introduces a new set of relations specifically developed to maintain conformity of conceptual abstractions with the nature of information abstractions implied by user requirements throughout the organization. Such relations are based on the stratification of work hierarchies, defined elsewhere in the thesis. Finally, an example of an application of the proposed approach is presented to illustrate the applicability and practicality of the modelling approach

Solving the Problematic Relationship between Irregular Marketing Behaviours and the Principles of Social Responsibility

Reckless marketing has recently become a dirty tool played by modern pirates with a network of gangs, as they tried hard to mix facts as poker cards are on the table, and its danger to social responsibility values has become very worrying in Iraq. Planning, tactics, probabilities and forecasting, and the Iraqi economy has become based on the unknown.Where, unfortunately, the mafia played in its squares, empty polemics from here and there, deceptions and tricks, until they entered the core of factories, and the inputs turned into numbers, and the operations turned into illusions, and the outputs were mere rubble, and the costs were huge, and the returns were despicableThen we continue.. Commercial projects are programmed viruses that strike any system, confuse all standards, destroy all walls of knowledge, and throw seeds of ignorance into the industrial environment instead of quality. We live in an era in which competition revolves around supply, demand, production, productivity, efficiency, effectiveness, knowledge and programming.But where are we in all of this?The companies of the world are looking for quality while we are digging for scrap? What led us to a culture of mediocre performance instead of outstanding performance? Is it an attempt to abort all academic efforts that theorize and strain themselves in solving puzzles and dilemmas to reach constructive proposals to heal the greatness, satisfy the great Creator, and strengthen the pillars and components of the desired Iraqi economy in light of volatile growth sources.This study came to reveal the current ambiguous situation in Iraq regarding the performance of deceptive companies that engage in spurious and irregular marketing activity and compare them with honest companies with real marketing and reward the second with its right and rights, and expose the first with all its sighs and stray breath Where the study was divided into three aspects, the first aspect focused on highlighting the methodology that followed the steps of the study and established the pillars and modalities of the research, while the second aspect focused on a theoretical account of the research variables and a review of the practical side, and we concluded with conclusions and recommendations

The Role of Strategic Brightness and Entrepreneurship in Achieving High Performance Gains

The current research deals with everything related to activating the contemporary leadership style for business organizations according to their modern models (developmental, results, integrative, personal), as the style is chosen according to the leader's strategic repertoire and his inspirational powers in a specific position.As a result of the rapid developments and rapid changes in recent years and the intensification of competition in the markets as a whole, which made most organizations guarantee for themselves survival and sustainability in the markets and the results of their work achieved by the management approach to controlling their work and this is done according to the perspective of ingenuity or organizational creativity with the support of their thinkers.From here, the researcher identified the problem of the research with the question that confirms the extent to which it is possible to benefit from the level of creativity in the minds of the leaders of our local institutions, and what is their role in getting rid of routine obstacles that increase organizational deterioration to reach the pioneering performance in all their businesses. The aim of the current research is to analyze and explore the degree of strategic brightness in the commercial sector in Basra, to diagnose the relative importance of the components of strategic leadership in the environment of commercial activity and to try to analyze the level of awareness of the issue of creativity as an initiative. The business of modern Basra, namely )Al-Madda and Al-Taif companies(, amounting to (25) individuals out of a total of (35) individuals, at a rate of (71%). Descriptive and inferential tests will be conducted, the aim of which is to test the correlation and influence relationships between the variables of strategic brightness and investment leadership to gain the benefits of high performance and competitive advantage based on creativity and leadership, starting from leading and extending towards the endless competition in the market

The Joyful Interaction Management Strategy to Beautify the Relationship with the Customer an Exploratory Study in Some Basra Hospitals

The current research directed towards testing a model designed by the researcher to reveal the extent of the possibility of beautifying medical procedures in hospitals from the perspective of relationship management or the joyful interaction with the customer, by focusing on the procedural dimension of the specialized human and professional interaction between the health service provider and its recipient, and conducting an administrative beautification process to get rid of the distortions of medical qualities in dealing For health care providers in local hospitals. The proposed model, which the researcher tried to test in the field of practicing medicine, with a focus on the College of Medicine in Basra, revolves around three main variables:The care of the departments or deanships of medical colleges in Iraq with the customer and the need to go towards him, and work on creating a broad (R) relationship that focuses on the customer’s value and happiness and meeting his needs, and embracing health activities in a way that meets the customer’s desires (C) whether they are actual or potential and mixing these concepts The three (mix). Through a survey of the opinions of people specialized in health performance and other parties related to the research to try to beautify the deformities that occurred in the health performance with a questionnaire prepared by the researcher and distributed to (120) individuals with a variety of assortment to represent a random sample of doctors, workers and students practicing the medical profession, trainees and their supervisors, and at a rate of (20) A form for each of the six Basra hospitals (Basra General Hospital, Basra Maternity and Children Hospital.Ibn Ghazwan, Shifa General Hospital, Al-Sadr Teaching Hospital, Al-Tahrir General Hospital, Al-Fayhaa General Hospital) in which practical lessons are applied and medical cases conducted by the College of Medicine for its students, which are factories of health and medical information and an effective field. For scientific and practical application and observations, with a response rate of (66%), the research concluded, after conducting the statistical analysis process through data processing with the statistical spss program, that the surveyed organizations’ interest in the variables of the proposed model was less than the level required to rise to the trend in applying the concepts of the customer relationship management strategy Similar to the trends of health organizations in the developed world. The research recommended that the administrative authorities in the education corridors that provide the service of science and medical and health knowledge in Iraq must adopt the concept of relationship management with the customer and the recognition that the customer is the focus of the desired success and its role is very important for the educational health organization, which is the basis of information that constitutes the building block of education, and does not determine its activities from Without considering the customer as a source on which to draw its future directions.Therefore, this research was divided into four aspects, the first concerned, with the conceptual approach, the second concerned with the methodological aspect while the third was devoted to the applied aspect, and we concluded with the fourth aspect, under which the conclusions and recommendations reached by the research

Preparedness, Raising the Level of Preparedness and Enhancing Contemporary Prevention Methods to Get Rid of the Risks of Deadly Health Crises and Their Implications for the Health of Workers

This study came to emphasize the importance of health promotion at the present time in all parts of the universe due to the federal movement witnessing the challenges of the Corona virus that originated from the Chinese city of Wuhan and spread in all countries of the world with amazing and terrifying speed (for bacterial, parasitic and viral causes) despite the WHO assurances Globalization with a high degree of responsibility, and this was evidenced by the calls and appeals of leaders of health organizations in the world for prevention, awareness, discussions and advice that they gave to all of humanity, as the virus has infected most of the world without exception between developed and developing countries alike. (In his speech, Tiedros Adhanom Gebresus is Secretary-General of the World Health Organization: February 27, 2020) As the virus evolved from the respiratory syndrome of the Middle East caused by cats to SARS, who moved between camels to Ebola and then developed to the most dangerous corona, which is transmitted between humans through touch, spray and breath, which has exceeded cases in the world to more than 600,000 patients with a confirmed infection And over 26 countries in the world until March 2020 and from here the researcher eagerly awaits the moment when investors announce their willingness to embrace any innovation related to the recovery from these epidemics. [15]. It is a logical result stemming from the feeling of great dismay that has caused mankind in recent times as a result of the outbreak of the Corona epidemic and the massive series of panic in all parts of the globe that left behind and the confusion that made the need to invent vaccines and ways to spread awareness in a timely and instant manner and seize the finest federal concept between the administration and the media related to the accident. The time is “Participate in the comprehensive awareness campaign and the highest levels of caution and caution” To achieve maximum benefit from it in combating, preventing, sterilizing, and identifying the most important pillars upon which it is based, and then showing the health benefits of workers in local organizations with a view to preserving them, and to achieve the desired benefit in sounding the work and promoting it with health by integrating administrative and health concepts with each other and circulating them through disseminating them Seminars and conferences in a manner that achieves the desired goal above: So this effort was divided as follows: Part one: will cover the systematic aspect of the study; The second part: He will be interested in presenting the concept, benefits and pillars of the essential participation; Part Three: He will examine the concepts of health promotion activities for institutions; Part Four: Examination and testing the feasibility of including the concept of substantive participation and activities of the health promotion unit; Part Five: Results, Conclusions and Recommendations. The study recommended the necessity of disseminating the health information in addition to the administrative information in all institutions and segments of society in order to address firmly the prejudiced rumors and ideas aimed at impeding the administrative and health growth in our local institutions

The Effect of Using the Art of Harmony and Synergy with Strategic and Cognitive Dimensions in Improving the Methods of Storming Competitors' Strategies

When I start talking about clarifying and explaining what distinguishes between the cognitive, social and performance capabilities of the leader, I must analyze the characteristics of leadership and management related to their perceptions of work activities represented in solving technical problems that arise in the field of administrative work by creating a style of harmony and coping, and the effect of the characteristics of his nature and the reflection of their upbringing on How to create an appropriate climate to contain the emergency situations that hinder the functional and production processes and try to find out whether they have the capabilities that direct it towards (Benchmarking) organizations that develop unique solutions to those situations or not?This study came as an attempt to present explanations and clarifications of the aforementioned by introducing scientific additions to what researchers have gone by, who contributed to drawing a roadmap, but they did not fully seize the opportunity, but rather left it for the coming intellectual generations to put touches on it that approach their reality and their era, which increases questions, ambiguity and challenges. The study aims to develop a (Head, heart, Legs) model for the contemporary managerial psychologist (Finn Havaleshka), which is one of the most important and pioneering scientific contributions in the field of managerial psychology that focuses on explaining the characteristics of individuals at the level of managerial decision-making (administrative and leadership) from By focusing on the cognitive and social aspects, and their impact on performance), let this study be an evolution of this model and an update of what this pioneering scientist started by adding a fourth stage to the model represented by the dimension of (Arms) or arms that defend the successes achieved through their maintenance and preservation. On the one hand, the situation is transferred to the offensive stage by expanding the area of success by using offensive strategies that invade the labor market, as it is said that the best defense is attack. The study was divided into three axes:The first axis focused on presenting the methodological aspect of the research, while the second focused on the available theorizing and the third covered the conclusions

Inhibitory Effect of Ethanolic Extract Isolated from Radix Pulasatillae Seeds against Proliferation of A549 Human Lung Cancer Cells

The present study was evaluated the anticancer activity of Radix Pulsatillae ethanol extract at first by using high throughput screening HTS for herb fractions screening in concentration of 100μM to identify the active fraction and then we measured the cytotoxic effects by using morphology changes, and detected apoptosis by Hoechst 33258 staining. Our results showed that Radix Pulsatillae ethanol extract has a strong toxicity against A549 lung cancer cells and low toxicity with mice normal splenocytes and requires more investigation to identify the small natural molecule with new anticancer activity and further mechanistic for cancer pathway