1,167 research outputs found
Soviet geographers and the Great Patriotic War, 1941–1945 : Lev Berg and Andrei Grigor'ev
AbstractThe significance of the Second World War for Soviet geography was somewhat different from that in much of the West. In the USSR, as a result of the 1917 Russian Revolution and, more particularly, of Joseph Stalin's ‘Great Turn’ implemented in 1929–1933, geographers were faced with pronounced political and economic challenges of a kind which arguably only confronted most Western geographers with the onset of war. It is therefore impossible to understand the impact of the war for Soviet geography without taking into account this broader context, including events during the turbulent post-war years. The paper will focus on the experiences of two prominent geographers who played a major role in the developments of the era including their responses to the revolutionary circumstances occurring from the late 1920s, their activities and experiences during the war, and the debates and conflicts they engaged in during the post-war crisis. Some of the more significant contrasts with geographical developments in Western countries during these years will be emphasized
Unraveling the effect of intra- and intercellular processes on acetaminophen-induced liver injury
In high dosages, acetaminophen (APAP) can cause severe liver damage, but susceptibility to liver failure varies across individuals and is influenced by factors such as health status. Because APAP-induced liver injury and recovery is regulated by an intricate system of intra- and extracellular molecular signaling, we here aim to quantify the importance of specific modules in determining the outcome after an APAP insult and of potential targets for therapies that mitigate adversity. For this purpose, we integrated hepatocellular acetaminophen metabolism, DNA damage response induction and cell fate into a multiscale mechanistic liver lobule model which involves various cell types, such as hepatocytes, residential Kupffer cells and macrophages. Our model simulations show that zonal differences in metabolism and detoxification efficiency are essential determinants of necrotic damage. Moreover, the extent of senescence, which is regulated by intracellular processes and triggered by extracellular signaling, influences the potential to recover. In silico therapies at early and late time points after APAP insult indicated that prevention of necrotic damage is most beneficial for recovery, whereas interference with regulation of senescence promotes regeneration in a less pronounced way.Toxicolog
A Russian geographical tradition? The contested canon of Russian and Soviet geography, 1884–1953
AbstractThe paper defines a ‘geographical canon’ as those texts and authors which have been regarded as authoritative by geographers active at particular points in time. The focus is on the development of a geographical canon in Russia and the Soviet Union between the establishment of the first university geography departments in the 1880s and Stalin's death in 1953. A key 1949 meeting of the Academy of Sciences, held at a crisis point in Soviet history, is initially highlighted. The meeting's purpose was to define a canon or list of ‘founding fathers’ for each of the Soviet sciences, including geography, accenting the Russian provenance of each science. In geography's case, the ‘founding father’ selected was the eminent soil scientist, V. V. Dokuchaev (1846–1903). The paper discusses Dokuchaev's scientific achievements and questions why he was considered such an important figure by the geographers of the late Stalin era. It then analyzes some of the key works of a number of prominent geographers of the pre-revolutionary and Stalinist periods to discover how far Dokuchaev's work was emphasized. The main finding is that, although Dokuchaev and his school did have an indirect influence on geographical work from early on, only from about 1930 was his importance emphasized whilst that of the Germans was largely erased by Stalinism. The conclusion is that the geographical canon defined in 1949 was less a genuine attempt to describe the history of the discipline than a response to the priorities of the late Stalin era
Cloud microphysical effects of turbulent mixing and entrainment
Turbulent mixing and entrainment at the boundary of a cloud is studied by
means of direct numerical simulations that couple the Eulerian description of
the turbulent velocity and water vapor fields with a Lagrangian ensemble of
cloud water droplets that can grow and shrink by condensation and evaporation,
respectively. The focus is on detailed analysis of the relaxation process of
the droplet ensemble during the entrainment of subsaturated air, in particular
the dependence on turbulence time scales, droplet number density, initial
droplet radius and particle inertia. We find that the droplet evolution during
the entrainment process is captured best by a phase relaxation time that is
based on the droplet number density with respect to the entire simulation
domain and the initial droplet radius. Even under conditions favoring
homogeneous mixing, the probability density function of supersaturation at
droplet locations exhibits initially strong negative skewness, consistent with
droplets near the cloud boundary being suddenly mixed into clear air, but
rapidly approaches a narrower, symmetric shape. The droplet size distribution,
which is initialized as perfectly monodisperse, broadens and also becomes
somewhat negatively skewed. Particle inertia and gravitational settling lead to
a more rapid initial evaporation, but ultimately only to slight depletion of
both tails of the droplet size distribution. The Reynolds number dependence of
the mixing process remained weak over the parameter range studied, most
probably due to the fact that the inhomogeneous mixing regime could not be
fully accessed when phase relaxation times based on global number density are
considered.Comment: 17 pages, 10 Postscript figures (figures 3,4,6,7,8 and 10 are in
reduced quality), to appear in Theoretical Computational Fluid Dynamic
Contribution of forbidden orbits in the photoabsorption spectra of atoms and molecules in a magnetic field
In a previous work [Phys. Rev. A \textbf{66}, 0134XX (2002)] we noted a
partial disagreement between quantum R-matrix and semiclassical calculations of
photoabsorption spectra of molecules in a magnetic field. We show this
disagreement is due to a non-vanishing contribution of processes which are
forbidden according to the usual semiclassical formalism. Formulas to include
these processes are obtained by using a refined stationary phase approximation.
The resulting higher order in contributions also account for previously
unexplained ``recurrences without closed-orbits''. Quantum and semiclassical
photoabsorption spectra for Rydberg atoms and molecules in a magnetic field are
calculated and compared to assess the validity of the first-order forbidden
orbit contributions.Comment: 12 pages, 6 figure
Totalitarianism and geography: L.S. Berg and the defence of an academic discipline in the age of Stalin
In considering the complex relationship between science and politics, the article focuses upon the career of the eminent Russian scholar, Lev Semenovich Berg (1876–1950), one of the leading geographers of the Stalin period. Already before the Russian Revolution, Berg had developed a naturalistic notion of landscape geography which later appeared to contradict some aspects of Marxist–Leninist ideology. Based partly upon Berg's personal archive, the article discusses the effects of the 1917 revolution, the radical changes which Stalin's cultural revolution (from the late 1920s) brought upon Soviet science, and the attacks made upon Berg and his concept of landscape geography thereafter. The ways in which Berg managed to defend his notion of geography (sometimes in surprisingly bold ways) are considered. It is argued that geography's position under Stalin was different from that of certain other disciplines in that its ideological disputes may have been regarded as of little significance by the party leaders, certainly by comparison with its practical importance, thus providing a degree of ‘freedom’ for some geographers at least analogous to that which has been described by Weiner (1999. A little corner of freedom: Russian nature protection from Stalin to Gorbachev. Berkeley: University of California Press) for conservationists. It is concluded that Berg and others successfully upheld a concept of scientific integrity and limited autonomy even under Stalinism, and that, in an era of ‘Big Science’, no modernizing state could or can afford to emasculate these things entirely
V.I. Vernadsky and the noosphere concept: Russian understandings of society-nature interaction
Recent Russian legislative and policy documentation concerning national progress towards sustainable development has suggested that the attainment of such a state would represent the first stage in the development of the noosphere as outlined by the Russian scientist Vladimir Ivanovich Vernadsky (1863–1945). This paper explores Vernadsky’s model of evolutionary change through a focus on his work on the biosphere and noosphere in an attempt to further understanding of the way in which Russia is approaching the concept of sustainable development in the contemporary period. It is argued that the official Russian interpretation of the noosphere idea tends to obscure the evolutionary and materialist foundations of Vernadsky’s biosphere–noosphere conceptualisation. At the same time, the concluding section of the paper suggests that the scope of Vernadsky’s work can be used to stimulate the search for a more coherent approach to work in areas of sustainable development and sustainability across the span of the social and physical sciences
Lorenz-like systems and classical dynamical equations with memory forcing: a new point of view for singling out the origin of chaos
A novel view for the emergence of chaos in Lorenz-like systems is presented.
For such purpose, the Lorenz problem is reformulated in a classical mechanical
form and it turns out to be equivalent to the problem of a damped and forced
one dimensional motion of a particle in a two-well potential, with a forcing
term depending on the ``memory'' of the particle past motion. The dynamics of
the original Lorenz system in the new particle phase space can then be
rewritten in terms of an one-dimensional first-exit-time problem. The emergence
of chaos turns out to be due to the discontinuous solutions of the
transcendental equation ruling the time for the particle to cross the
intermediate potential wall. The whole problem is tackled analytically deriving
a piecewise linearized Lorenz-like system which preserves all the essential
properties of the original model.Comment: 48 pages, 25 figure
Degradation and healing in a generalized neo-Hookean solid due to infusion of a fluid
The mechanical response and load bearing capacity of high performance polymer
composites changes due to diffusion of a fluid, temperature, oxidation or the
extent of the deformation. Hence, there is a need to study the response of
bodies under such degradation mechanisms. In this paper, we study the effect of
degradation and healing due to the diffusion of a fluid on the response of a
solid which prior to the diffusion can be described by the generalized
neo-Hookean model. We show that a generalized neo-Hookean solid - which behaves
like an elastic body (i.e., it does not produce entropy) within a purely
mechanical context - creeps and stress relaxes when infused with a fluid and
behaves like a body whose material properties are time dependent. We
specifically investigate the torsion of a generalized neo-Hookean circular
cylindrical annulus infused with a fluid. The equations of equilibrium for a
generalized neo-Hookean solid are solved together with the convection-diffusion
equation for the fluid concentration. Different boundary conditions for the
fluid concentration are also considered. We also solve the problem for the case
when the diffusivity of the fluid depends on the deformation of the generalized
neo-Hookean solid.Comment: 24 pages, 10 figures, submitted to Mechanics of Time-dependent
Material
Protected areas support more species than unprotected areas in Great Britain, but lose them equally rapidly
Protected areas are a key conservation tool, yet their effectiveness at maintaining biodiversity through time is rarely quantified. Here, we assess protected area effectiveness across sampled portions of Great Britain (primarily England) using regionalized (protected vs unprotected areas) Bayesian occupancy-detection models for 1238 invertebrate species at 1 km resolution, based on ~1 million occurrence records between 1990 and 2018. We quantified species richness, species trends, and compositional change (temporal beta diversity; decomposed into losses and gains). We report results overall, for two functional groups (pollinators and predators), and for rare and common species. Whilst we found that protected areas have 15 % more species on average than unprotected ones, declines in occupancy are of similar magnitude and species composition has changed 27 % across protected and unprotected areas, with losses dominating gains. Pollinators have suffered particularly severe declines. Still, protected areas are colonized by more locally-novel pollinator species than unprotected areas, suggesting that they might act as ‘landing pads’ for range-shifting pollinators. We find almost double the number of rare species in protected areas (although rare species trends are similar in protected and unprotected areas); whereas we uncover disproportionately steep declines for common species within protected areas. Our results highlight strong invertebrate reorganization and loss across both protected and unprotected areas. We therefore call for more effective protected areas, in combination with wider action, to bend the curve of biodiversity loss – where we provide a toolkit to quantify effectiveness. We must grasp the opportunity to effectively conserve biodiversity through time
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