Invitation to opening ceremony of the new Sharyland building and photographs of the first turn of the dirt at the site

Invitation to opening ceremony of the new Sharyland building and photographs of the first turn of the dirt at the site. Companies housed in building are: Shary-Maddox Company, Texas Citrus Fruit Growers Exchange, Shary Products Company, The Brogdex Company of Texas, United Irrigation Company, Sharyland Orchards and Nurseries, Southtex Mortgage Loan Company, Granjeno Development Company.https://scholarworks.utrgv.edu/johnshary/1044/thumbnail.jp

Correspondence from John H. Shary to Dr. S. Sprecher

Correspondence discussing condition of crops, amount of water used, United Irrigation Company hardships, and livelihood of the renter.https://scholarworks.utrgv.edu/johnshary/1061/thumbnail.jp

Correspondence regarding finances

A handwritten letter to John H. Shary about finances. John H. Shary replies to the client in another letter.https://scholarworks.utrgv.edu/johnshary/1007/thumbnail.jp

Dedication speech for the opening of the new Sharyland school

Typed dedication speech delivered by Mr. John H. Shary. One of many speeches delivered during the dedication.https://scholarworks.utrgv.edu/johnshary/1030/thumbnail.jp

Bacterial protein meta-interactomes predict cross-species interactions and protein function

Background Protein-protein interactions (PPIs) can offer compelling evidence for protein function, especially when viewed in the context of proteome-wide interactomes. Bacteria have been popular subjects of interactome studies: more than six different bacterial species have been the subjects of comprehensive interactome studies while several more have had substantial segments of their proteomes screened for interactions. The protein interactomes of several bacterial species have been completed, including several from prominent human pathogens. The availability of interactome data has brought challenges, as these large data sets are difficult to compare across species, limiting their usefulness for broad studies of microbial genetics and evolution. Results In this study, we use more than 52,000 unique protein-protein interactions (PPIs) across 349 different bacterial species and strains to determine their conservation across data sets and taxonomic groups. When proteins are collapsed into orthologous groups (OGs) the resulting meta-interactome still includes more than 43,000 interactions, about 14,000 of which involve proteins of unknown function. While conserved interactions provide support for protein function in their respective species data, we found only 429 PPIs (~1% of the available data) conserved in two or more species, rendering any cross-species interactome comparison immediately useful. The meta-interactome serves as a model for predicting interactions, protein functions, and even full interactome sizes for species with limited to no experimentally observed PPI, including Bacillus subtilis and Salmonella enterica which are predicted to have up to 18,000 and 31,000 PPIs, respectively. Conclusions In the course of this work, we have assembled cross-species interactome comparisons that will allow interactomics researchers to anticipate the structures of yet-unexplored microbial interactomes and to focus on well-conserved yet uncharacterized interactors for further study. Such conserved interactions should provide evidence for important but yet-uncharacterized aspects of bacterial physiology and may provide targets for anti-microbial therapies

Sharyland (view book)

From the inside cover The following views are faithful reproductions of genuine photographs of some of the many objects of interest to be seen on the John H. Shary Subdivision and other points of in the Lower Rio Grande Valley. View book contains 40 pages printed in black and white with brief captions (left) and photographs (right).https://scholarworks.utrgv.edu/johnshary/1113/thumbnail.jp