17,687 research outputs found
A suggested course of study in farm mechanics for high schools, based on the opinions of five hundred farmers
Typescript (photocopy) Thesis (M.S.)--Iowa State College, 1928. Includes bibliography
Unsung heroes: who supports social work students on placement?
Since the introduction of the three year degree programme in 2003, social work education has undergone a number of significant changes. The time students spend on placement has been increased to two hundred days, and the range of placement opportunities and the way in which these placements have been configured has significantly diversified. A consistent feature over the years, however, has been the presence of a Practice Educator (PE) who has guided, assessed and taught the student whilst on placement. Unsurprisingly, the role of the PE and the pivotal relationship they have with the student has been explored in the past and features in social work literature.
This paper, however, concentrates on a range of other relationships which are of significance in providing support to students on placement. In particular it draws on research to discuss the role of the university contact tutor, the place of the wider team in which the student is sited, and the support offered by family, friends and others.
Placements and the work undertaken by PE’s will continue to be integral to the delivery of social work education. It is, however, essential to recognise and value the often over looked role of others in providing support to students on placement
Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains
BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks created many decades ago; however their genotypes, underlying mechanisms and relative degree of their attenuation are largely unknown.
RESULTS: Using mouse virulence studies we confirm that MAP vaccine strains 316 F, II and 2e have diverse but clearly attenuated survival and persistence characteristics compared with wild type strains. Using a pan genomic microarray we characterise the genomic variations in a panel of vaccine strains sourced from stocks spanning over 40 years of maintenance. We describe multiple genomic variations specific for individual vaccine stocks in both deletion (26-32 Kbp) and tandem duplicated (11-40 Kbp) large variable genomic islands and insertion sequence copy numbers. We show individual differences suitable for diagnostic differentiation between vaccine and wild type genotypes and provide evidence for functionality of some of the deleted MAP-specific genes and their possible relation to attenuation.
CONCLUSIONS: This study shows how culture environments have influenced MAP genome diversity resulting in large tandem genomic duplications, deletions and transposable element activity. In combination with classical selective systematic subculture this has led to fixation of specific MAP genomic alterations in some vaccine strain lineages which link the resulting attenuated phenotypes with deficiencies in high reactive oxygen species handling
The Role of Solar Wind Hydrogen in Space Weathering: Insights from Laboratory-Irradiated Northwest Africa 12008
Micrometeoroid impacts, solar wind plasma interactions, and regolith gardening drive the complicated and nuanced mechanism of space weathering (or optical maturation); a process by which a materials optical properties are changed as a result of chemical and physical alterations at the surface of grains on airless bodies. Reddened slopes, attenuated absorption bands, and an overall reduction in albedo in the visible and near-IR wavelength ranges are primarily the result of native iron nanoparticle (npFe0) production within glassy rims that form from sputtering and vaporization. The sizes and abundance of these particles provide information about the relative surface exposure age of a particular grain. In addition, many studies have indicated that composition greatly affects the rate at which optical maturation occurs. Despite our understanding of how npFe0 affects optical signatures, the relative roles of micrometeoroid bombardment and solar wind interactions remains undetermined. To simulate the early effects of weathering by the solar wind and to determine thresholds for optical change with respect to a given mineral phase, we irradiated a fine-grained lunar basalt with 1 keV H+ to a fluence of 6.4 x 1016 H+ per sq.cm. Surface alterations within four phases have been evaluated using transmission electron microscopy (TEM). We found that for a given fluence of H+, the extent of damage acquired by each grain was dependent on its composition. No npFe(0) was produced in any of the phases evaluated in this study. These results are consistent with many previous studies conducted using ions of similar energy, but they also provide valuable information about the onset of space weathering and the role of the solar wind during the early stages of optical maturation
Spectroscopic Constants, Abundances, and Opacities of the TiH Molecule
Using previous measurements and quantum chemical calculations to derive the
molecular properties of the TiH molecule, we obtain new values for its
ro-vibrational constants, thermochemical data, spectral line lists, line
strengths, and absorption opacities. Furthermore, we calculate the abundance of
TiH in M and L dwarf atmospheres and conclude that it is much higher than
previously thought. We find that the TiH/TiO ratio increases strongly with
decreasing metallicity, and at high temperatures can exceed unity. We suggest
that, particularly for subdwarf L and M dwarfs, spectral features of TiH near
0.52 \mic, 0.94 \mic, and in the band may be more easily measureable
than heretofore thought. The recent possible identification in the L subdwarf
2MASS J0532 of the 0.94 \mic feature of TiH is in keeping with this
expectation. We speculate that looking for TiH in other dwarfs and subdwarfs
will shed light on the distinctive titanium chemistry of the atmospheres of
substellar-mass objects and the dimmest stars.Comment: 37 pages, including 4 figures and 13 tables, accepted to the
Astrophysical Journa
Onset of Phase Synchronization in Neurons Conneted via Chemical Synapses
We study the onset of synchronous states in realistic chaotic neurons coupled
by mutually inhibitory chemical synapses. For the realistic parameters, namely
the synaptic strength and the intrinsic current, this synapse introduces
non-coherences in the neuronal dynamics, yet allowing for chaotic phase
synchronization in a large range of parameters. As we increase the synaptic
strength, the neurons undergo to a periodic state, and no chaotic complete
synchronization is found.Comment: to appear in Int. J. Bif. Chao
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