Vibrio ponticus, a new pathogen of cultured cobia

Most of the members of the family Vibrionaceae are natural inhabitants of marine and estuarine ecosystem and several of them are pathogens in cultured aquatic organisms. Vibriosis caused by some pathogenic Vibrio spp., can cause huge mortality in marine fish culture systems. Intermittent mortality with haemorrhagic lesions on the fin, body surface, and head, exophthalmia (Fig.1) and stopping of feeding activity were noticed in cobia (25±5 cm length; 17±4 g weight) reared in sea cages off Polem, Goa during June 2015. The clinical signs lasted for a week with a total mortality of 12%. Isolation of bacteria aseptically from liver and kidney was done

Nursery rearing of Asian Seabass

Lates calcarifer species is widely distributed in the tropical and subtropical areas of the western Pacific and Indian ocean including Australia, Southeast Asia, the Philippines and countries bordering the Arabian sea. Seabass spend most of their life in a lagoon which connects to the sea. They spend two to three more years in estuarine areas until they mature, then migrate to the sea water around the mouth of a river or lagoon for spawning. Larvae and juveniles live in the sea grass bed in coastal areas for about six months, attaining a size of about 2 to 5 inches. The fish migrate to freshwater when they grow bigger

MANAGEMENT OF AUTISM SPECTRUM DISORDER WITH ABHAYAGHRITA AND PANCHA BHAUTIKA TAILANASYA- A CASE REPORT

Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental condition with its onset before the age of three years. It is characterized by abnormalities in communication, impaired social function, repetitive behaviours and restricted interests. There is no effective treatment currently available for ASD and there is a growing need of an alternative treatment modality. A three year six month old male patient, diagnosed with ASD was brought to the OPD for Ayurvedic treatment of ASD. There is no mention of ASD in Ayurveda classics and hence, considered an Anukta Vyadhi. ASD involves vitiation of all the three Doshas mainly Vata Dosha in the lead. The management was primarily based on the associated Doshas and Ayurvedic formulations i.e. Abhaya Ghrita orally for three months and Marsha Nasya with Panchabhautika Taila for forty five days were used. Changes in the clinical features were assessed using Aberrant Behaviour Checklist (ABC) and changes in the severity of disease after treatment was done using Clinical Global Impression scale (CGI). The patient showed significant improvement in the core features of ASD after the treatment duration

A Cell-Based Protein-Protein Interaction Method Using a Permuted Luciferase Reporter

We have developed a novel cell-based protein-protein interaction assay method. The method relies on conversion of an inactive permuted luciferase containing a Tobacco Etch Virus protease (TEV) cleavage sequence fused onto protein (A) to an active luciferase upon interaction and cleavage by another protein (B) fused with the TEV protease. We demonstrate assay applicability for ligand-induced protein-protein interactions including G-protein coupled receptors, receptor tyrosine kinases and nuclear hormone receptors

Improving the Optical and Thermoelectric Properties of Cs2InAgCl6 with Substitutional Doping: A DFT Insight

New generation Indium based lead-free Cs2InAgCl6 is a promising halide material in photovoltaic applications due to its good air stability and non-toxic behavior. But its wide band gap (>3 eV) is not suitable for solar spectrum and hence reducing the photoelectronic efficiency for device applications. Here we report a significant band gap reduction from 3.3 eV to 0.6 eV by substitutional doping and its effect on opto-electronic and opto-thermoelectric properties from first-principles study. The results predict that Sn/Pb and Ga & Cu co-doping enhance the density of states significantly near the valence band maximum (VBM) and thus reduce the band gap by shifting the VBM upward while the alkali-metals (K/Rb) slightly increase the band gap. A strong absorption peak near Shockley-Queisser limit is observed in co-doped case while in Sn/Pb-doped case, we notice a peak in the middle of the visible region of solar spectrum. The nature of band gap is indirect with Cu-Ga/Pb/Sn doping with a significant reduction in the band gap. We observe a significant increase in the power factor (PF) (2.03 mW/mK2) for n-type carrier in Pb-dpoing, which is ~3.5 times higher than the pristine case (0.6 mW/mK2) at 500 K

Evaluation of the Effectiveness of Telemedicine in Postoperative Follow-Up Care After Dental Implant Surgery. A Pilot Study

AIM: Telemedicine has emerged as a potential solution to enhance postoperative follow-up care after dental implant surgery, offering the convenience of remote monitoring and reduced need for in-person visits. MATERIALS AND METHODS: Participants were randomly assigned to either the telemedicine group (n = 15) or the in-person group (n = 15). In the telemedicine group, patients received remote follow-up care through virtual consultations, during which they could communicate their concerns and share images of the surgical site. The in-person group received standard in-person follow-up visits. Patient satisfaction was measured using a standardized survey, with responses collected on a Likert scale. RESULTS: Telemedicine group exhibited comparable levels of patient satisfaction (mean satisfaction score ± standard deviation: 4.6 ± 0.3) to the in-person group (4.7 ± 0.2). Moreover, clinical outcomes, including wound healing assessment, were similar between the two groups. No significant differences were observed in the incidence of postoperative complications or the need for additional interventions. CONCLUSION: In conclusion, this pilot study demonstrates that telemedicine is an effective alternative to traditional in-person follow-up care for postoperative dental implant surgery patients. It offers comparable patient satisfaction and clinical outcomes while proving to be more cost-effective

Note on the ocean sunfish, Mola mola (Linnaeus, 1758) landed at Karwar, west coast of India

The spine tail devil ray Mobula japanica (Muller & Henle, 1841) is a large zooplanktivorous ray circumglobally distributed within tropical to warm temperate waters. This species belong to the family Mobulidae. In the genus Mobula, the mouth is located ventrally and is currently represented by nine recognised species

Risso's dolphin Grampus griseus, (Cuvier, 1812) rescued off Aligadda Beach, Karwar, Karnataka

On 23rd August 2013, a Risso’s Dolphin was nearly stranded on the Aligadda beach, Karwar. The dolphin appeared to be under stress and it was coming towards the shore. On seeing the dolphin, the local fishermen dragged it into the deeper waters to rescue. This dolphin is locally known as “God’s fish”, and hence the rescue operation was carried out by the local fishermen