278 research outputs found
That Baboon Baby Dance / music by Joe Cooper; words by Dave Oppenheim
Cover: a drawing of baboons playing; Publisher: Shapiro Music Pub. Co. (New York)https://egrove.olemiss.edu/sharris_c/1036/thumbnail.jp
(The Song That I Heard In My Childhood) That\u27s The Song For Me / music by Nat. Osborne; words by Joe Goodwin
Cover: a photo of a mother and her child, floral illustration; Publisher: Shapiro Bernstein and Co. (New York)https://egrove.olemiss.edu/sharris_c/1097/thumbnail.jp
(There\u27s a Light That\u27s Burning in the Window of) The Little House Upon the Hill / words by Ballard Mc Donald, Joe Goodwin, and Harry Puck
Cover: drawing of an elderly lady sitting on a bench near a dog, a house is centered in the background; photo inset of Ward and Delmore; Publisher: Shapiro Bernstein and Co. (New York)https://egrove.olemiss.edu/sharris_c/1075/thumbnail.jp
Predictors of rater bias in the assessment of social-emotional competence
The Devereux Student Strengths Assessment Mini (DESSA-Mini) (LeBuffe, Shapiro, &
Naglieri, 2014) efficiently monitors the growth of Social-Emotional Competence (SEC)
in the routine implementation of Social Emotional Learning programs. The DESSAMini
is used to assess approximately half a million children around the world. Since
behavior rating scales can have ‘rater bias’, this paper examines rater characteristics that
contribute to DESSA-Mini ratings. Rater characteristics and DESSA-Mini ratings were
collected from elementary school classroom teachers (n=72) implementing TOOLBOX
in a racially/ethnically diverse California school district. Teachers rated 1,676 students,
who scored similarly to a national reference group. Multilevel modeling analysis showed
that only 16% of variance in DESSA-mini ratings was attributable to raters.
Relationships between teacher characteristics and ratings were estimated to examine
rater variance. Collectively, four characteristics of teachers (perceived barriers to student
learning, sense of their ‘typical’ student’s level of SEC, anticipation of SEL program
implementation challenges, and intentions to fully implement a newly adopted SEL
program) accounted for bias in teacher-generated DESSA scores, leaving only 10% of
the variance unexplained. Identified sources of ‘rater bias’ can be controlled for in
research and addressed through thoughtful program selection, training, and
implementation.peer-reviewe
Na/K-ATPase mimetic pNaKtide Peptide inhibits the growth of human cancer cells
Cells contain a large pool of non-pumping Na/K-ATPase that participates in signal transduction. Here, we show that the expression of α1 Na/K-ATPase is significantly reduced in human prostate carcinoma as well as in several human cancer cell lines. This down-regulation impairs the ability of Na/K-ATPase to regulate Src-related signaling processes. Supplement of pNaKtide, a peptide derived from α1 Na/K-ATPase, reduces activities of Src and Src effectors. Consequently, these treatments stimulate apoptosis and inhibit growth in cultures of human cancer cells. Moreover, administration of pNaKtide inhibits angiogenesis and growth of tumor xenograft. Thus, the new findings demonstrate the in vivo effectiveness of pNaKtide, and suggest that the defect in Na/K-ATPase-mediated signal transduction may be targeted for developing new anti-cancer therapeutics
Recommended from our members
Recombination in the Open-Ended Value Landscape of Digital Innovation
Digital innovation introduces a new open-ended value landscape to anyone seeking to generate or capture new value. To understand this landscape, we distinguish between design recombination and use recombination, explore how they play out together, and redirect the attention from products and services toward digital resources. Digital resources serve as building-blocks in digital innovation, and they hold the potential to simultaneously be part of multiple value paths, offered through design recombination and assembled through use recombination. Building on this perspective, we offer the value spaces framework as a tool for better understanding value creation and capture in digital innovation. We illustrate the framework and offer the early contours of a research agenda for information systems researchers
- …