An Emotional Skills Intervention for Elementary Children with Autism in China: A Pilot Study

The purpose of this pilot study was to examine the effects of an emotional skills intervention on behavioral and emotional competence, as well as on communication for children with autism in China. Eight children (seven boys and one girl), aged 7 to 8, participated in this study. We used a pre and posttest group design. The intervention consisted of 10 group sessions and four individual sessions. Each group session had two or three children. The intervention curriculum consisted of emotion recognition, emotion recognition within context, self-expression of emotions, seeking help when encountering problems, and techniques for emotion regulation. Results indicated that the intervention significantly improved children’s emotional skills, behavioral and emotional competence, and communication. The potential implications of this study for elementary children with autism in China are also discussed

Phosphomolybdic acid-responsive Pickering emulsions stabilized by ionic liquid functionalized Janus nanosheets

<p><b>A</b> Representative photomicrographs of Caspase-3 immunofluorescence staining (400×). <b>B</b> Quantification of Caspase-3 fluorescence intensity in different groups. <b>C</b> Representative Western blot band of Caspase-3 activation in the ischemic cortex at 24 h after reperfusion. <b>D</b> Effect of LBP (40 mg/kg) on the Caspase-3 activation in MCAO mice cortex at 24 h after reperfusion. Data are expressed as mean±SEM (n = 6). ^##P<0.01 vs. sham-operated group; **P<0.01 vs. vehicle group.</p

Protective effect of LBP against cerebral ischemic injury in MCAO mice brains.

<p><b>A</b> TTC staining of representative coronal sections at 24<b>B</b> Quantitative analysis of infarct volumes at 24 h after reperfusion. <b>C</b> Quantification of neurologic scores at 24 h after reperfusion. Data are expressed as mean±SEM (n = 6). ^##P<0.01, vs. sham-operated group, * P<0.05, **P<0.01 vs. vehicle group.</p

LBP reduces the number of Tunel positive neurons after focal cerebral ischemic injury.

<p><b>A</b> TUNEL staining of representative sections in mice ischemic penumbra of the cortex at 24<b>B</b> Quantitative analysis of apoptosis cells in cortex in different groups at 24 h after reperfusion. Data are expressed as mean±SEM (n = 6). ^##P<0.01 vs. sham-operated group; *P<0.05, **P<0.01 vs. vehicle group.</p

Effect of LBP treatment on morphological changes in ischemic penumbra of the cortex at 24-eosin staining (400×).

<p>A Sham-operated group. B Vehicle group. C LBP 10 mg/kg group. D LBP 20mg/kg group. E LBP 40mg/kg group. F Nimodipine 0.4mg/kg group.</p

Effects of LBP on the expression of Bcl-2 protein.

<p><b>A</b> Representative photomicrographs of Bcl-2 immunofluorescence staining (400×). <b>B</b> Quantification of Bcl-2 protein fluorescence intensity in different groups. <b>C</b> Representative Western blot band of Bcl-2 protein expression in the ischemic cortex at 24 h after reperfusion. <b>D</b> Effect of LBP (40 mg/kg) on the Bcl-2 expression in MCAO mice cortex at 24 h after reperfusion. Data are expressed as mean±SEM (n = 6). ^#P<0.05, ^##P<0.01 vs. sham-operated group; **P<0.01 vs. vehicle group.</p

Effects of LBP on the expression of CytC.

<p><b>A</b> Representative photomicrographs of CytC immunofluorescence staining (400×). <b>B</b> Quantification of CytC fluorescence intensity in different groups. <b>C</b> Representative Western blot band of CytC activation in the ischemic cortex at 24 h after reperfusion. <b>D</b> Effect of LBP (40 mg/kg) on the CytC activation in MCAO mice cortex at 24 h after reperfusion. Data are expressed as mean±SEM (n = 6). ^##P<0.01 vs. sham-operated group; *P<0.05, **P<0.01 vs. vehicle group.</p