8 research outputs found
Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone
No full textZika virus (ZIKV) infection is an
emerging pandemic threat to humans
that can be fatal in newborns. Advances in digital health systems
and nanoparticles can facilitate the development of sensitive and
portable detection technologies for timely management of emerging
viral infections. Here we report a nanomotor-based bead-motion cellphone
(NBC) system for the immunological detection of ZIKV. The presence
of virus in a testing sample results in the accumulation of platinum
(Pt)-nanomotors on the surface of beads, causing their motion in H<sub>2</sub>O<sub>2</sub> solution. Then the virus concentration is detected
in correlation with the change in beads motion. The developed NBC
system was capable of detecting ZIKV in samples with virus concentrations
as low as 1 particle/μL. The NBC system allowed a highly specific
detection of ZIKV in the presence of the closely related dengue virus
and other neurotropic viruses, such as herpes simplex virus type 1
and human cytomegalovirus. The NBC platform technology has the potential
to be used in the development of point-of-care diagnostics for pathogen
detection and disease management in developed and developing countries
Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone
No full textZika virus (ZIKV) infection is an
emerging pandemic threat to humans
that can be fatal in newborns. Advances in digital health systems
and nanoparticles can facilitate the development of sensitive and
portable detection technologies for timely management of emerging
viral infections. Here we report a nanomotor-based bead-motion cellphone
(NBC) system for the immunological detection of ZIKV. The presence
of virus in a testing sample results in the accumulation of platinum
(Pt)-nanomotors on the surface of beads, causing their motion in H<sub>2</sub>O<sub>2</sub> solution. Then the virus concentration is detected
in correlation with the change in beads motion. The developed NBC
system was capable of detecting ZIKV in samples with virus concentrations
as low as 1 particle/μL. The NBC system allowed a highly specific
detection of ZIKV in the presence of the closely related dengue virus
and other neurotropic viruses, such as herpes simplex virus type 1
and human cytomegalovirus. The NBC platform technology has the potential
to be used in the development of point-of-care diagnostics for pathogen
detection and disease management in developed and developing countries
Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone
No full textZika virus (ZIKV) infection is an
emerging pandemic threat to humans
that can be fatal in newborns. Advances in digital health systems
and nanoparticles can facilitate the development of sensitive and
portable detection technologies for timely management of emerging
viral infections. Here we report a nanomotor-based bead-motion cellphone
(NBC) system for the immunological detection of ZIKV. The presence
of virus in a testing sample results in the accumulation of platinum
(Pt)-nanomotors on the surface of beads, causing their motion in H<sub>2</sub>O<sub>2</sub> solution. Then the virus concentration is detected
in correlation with the change in beads motion. The developed NBC
system was capable of detecting ZIKV in samples with virus concentrations
as low as 1 particle/μL. The NBC system allowed a highly specific
detection of ZIKV in the presence of the closely related dengue virus
and other neurotropic viruses, such as herpes simplex virus type 1
and human cytomegalovirus. The NBC platform technology has the potential
to be used in the development of point-of-care diagnostics for pathogen
detection and disease management in developed and developing countries
Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone
No full textZika virus (ZIKV) infection is an
emerging pandemic threat to humans
that can be fatal in newborns. Advances in digital health systems
and nanoparticles can facilitate the development of sensitive and
portable detection technologies for timely management of emerging
viral infections. Here we report a nanomotor-based bead-motion cellphone
(NBC) system for the immunological detection of ZIKV. The presence
of virus in a testing sample results in the accumulation of platinum
(Pt)-nanomotors on the surface of beads, causing their motion in H<sub>2</sub>O<sub>2</sub> solution. Then the virus concentration is detected
in correlation with the change in beads motion. The developed NBC
system was capable of detecting ZIKV in samples with virus concentrations
as low as 1 particle/μL. The NBC system allowed a highly specific
detection of ZIKV in the presence of the closely related dengue virus
and other neurotropic viruses, such as herpes simplex virus type 1
and human cytomegalovirus. The NBC platform technology has the potential
to be used in the development of point-of-care diagnostics for pathogen
detection and disease management in developed and developing countries
Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone
No full textZika virus (ZIKV) infection is an
emerging pandemic threat to humans
that can be fatal in newborns. Advances in digital health systems
and nanoparticles can facilitate the development of sensitive and
portable detection technologies for timely management of emerging
viral infections. Here we report a nanomotor-based bead-motion cellphone
(NBC) system for the immunological detection of ZIKV. The presence
of virus in a testing sample results in the accumulation of platinum
(Pt)-nanomotors on the surface of beads, causing their motion in H<sub>2</sub>O<sub>2</sub> solution. Then the virus concentration is detected
in correlation with the change in beads motion. The developed NBC
system was capable of detecting ZIKV in samples with virus concentrations
as low as 1 particle/μL. The NBC system allowed a highly specific
detection of ZIKV in the presence of the closely related dengue virus
and other neurotropic viruses, such as herpes simplex virus type 1
and human cytomegalovirus. The NBC platform technology has the potential
to be used in the development of point-of-care diagnostics for pathogen
detection and disease management in developed and developing countries
Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone
No full textZika virus (ZIKV) infection is an
emerging pandemic threat to humans
that can be fatal in newborns. Advances in digital health systems
and nanoparticles can facilitate the development of sensitive and
portable detection technologies for timely management of emerging
viral infections. Here we report a nanomotor-based bead-motion cellphone
(NBC) system for the immunological detection of ZIKV. The presence
of virus in a testing sample results in the accumulation of platinum
(Pt)-nanomotors on the surface of beads, causing their motion in H<sub>2</sub>O<sub>2</sub> solution. Then the virus concentration is detected
in correlation with the change in beads motion. The developed NBC
system was capable of detecting ZIKV in samples with virus concentrations
as low as 1 particle/μL. The NBC system allowed a highly specific
detection of ZIKV in the presence of the closely related dengue virus
and other neurotropic viruses, such as herpes simplex virus type 1
and human cytomegalovirus. The NBC platform technology has the potential
to be used in the development of point-of-care diagnostics for pathogen
detection and disease management in developed and developing countries
Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone
No full textZika virus (ZIKV) infection is an
emerging pandemic threat to humans
that can be fatal in newborns. Advances in digital health systems
and nanoparticles can facilitate the development of sensitive and
portable detection technologies for timely management of emerging
viral infections. Here we report a nanomotor-based bead-motion cellphone
(NBC) system for the immunological detection of ZIKV. The presence
of virus in a testing sample results in the accumulation of platinum
(Pt)-nanomotors on the surface of beads, causing their motion in H<sub>2</sub>O<sub>2</sub> solution. Then the virus concentration is detected
in correlation with the change in beads motion. The developed NBC
system was capable of detecting ZIKV in samples with virus concentrations
as low as 1 particle/μL. The NBC system allowed a highly specific
detection of ZIKV in the presence of the closely related dengue virus
and other neurotropic viruses, such as herpes simplex virus type 1
and human cytomegalovirus. The NBC platform technology has the potential
to be used in the development of point-of-care diagnostics for pathogen
detection and disease management in developed and developing countries
Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone
No full textZika virus (ZIKV) infection is an
emerging pandemic threat to humans
that can be fatal in newborns. Advances in digital health systems
and nanoparticles can facilitate the development of sensitive and
portable detection technologies for timely management of emerging
viral infections. Here we report a nanomotor-based bead-motion cellphone
(NBC) system for the immunological detection of ZIKV. The presence
of virus in a testing sample results in the accumulation of platinum
(Pt)-nanomotors on the surface of beads, causing their motion in H<sub>2</sub>O<sub>2</sub> solution. Then the virus concentration is detected
in correlation with the change in beads motion. The developed NBC
system was capable of detecting ZIKV in samples with virus concentrations
as low as 1 particle/μL. The NBC system allowed a highly specific
detection of ZIKV in the presence of the closely related dengue virus
and other neurotropic viruses, such as herpes simplex virus type 1
and human cytomegalovirus. The NBC platform technology has the potential
to be used in the development of point-of-care diagnostics for pathogen
detection and disease management in developed and developing countries
