Antimicrobial Activity Of New Synthetic Derivative Of Sesamol And Sesamum Indicum Seeds Extract Against Meningitis Causing Bacteria

The facts over S. aureus and E. coli to cause meningitis, and the antimicrobial potential of Sesame seeds and Sesamol were motivation for present study to compare the antibacterial potential of new synthetic derivativeof Sesamol (SDS) and Sesamum indicum seeds extract against meningitis causing bacteria (MCB). Present study involved synthesis of SDS and preparation of sesame seeds extract. The SDS was characterized using ATR-IR, 1H-NMR and Mass spectrometric data. Both SDS and sesame extract were tested for the inhibitory potential against MCB, namely: S. aureus and E. coli. Among both, the SDS exhibited higher inhibitory potential when compared with sesame extract. Based on the results present study concludes that SDS possess high inhibition potential against MCB and recommends that SDSmust be further evaluated for its clinical significance

Response Of New Sesamol Analogue And Sesamum Indicum Seeds Extract Against Meningitis Triggering Pathogens

A certain type of bacteria can cause an upper respiratory tract infection and then travel through the bloodstream to brain and can result in meningitis. Evidence over S. aureus and E. coli to trigger meningitis, antimicrobial potential of Sesamum indicumplant and sesamol intended present study to compare the antimicrobial response of new sesamol analogue (NSA) and Sesamum indicum seeds extract against meningitis triggering pathogens (MTP). Present study involved synthesis of NSA and preparation of sesame seeds extract (SSE). The NSA was characterized using ATR-IR, 1H-NMR and Mass spectrometric data. Both NSA and SSE were tested for antimicrobial potential against MTP, namely: S. aureus and E. coli. Among both, the NSA exhibited much higher antimicrobial potential when compared with SSE. Based on the resultant data present study concludes that NSA possess high inhibition potential against MTP and recommends that NSA should be further evaluated to support its clinical importance