5 research outputs found

    Design of Short Synchronization Codes for Use in Future GNSS System

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    The prolific growth in civilian GNSS market initiated the modernization of GPS and the GLONASS systems in addition to the potential deployment of Galileo and Compass GNSS system.The modernization efforts include numerous signal structure innovations to ensure better performances over legacy GNSS system. The adoption of secondary short synchronization codes is one among these innovations that play an important role in spectral separation, bit synchronization, and narrowband interference protection. In this paper, we present a short synchronization code design based on the optimization of judiciously selected performance criteria. The new synchronization codes were obtained for lengths up to 30 bits through exhaustive search and are characterized by optimal periodic correlation. More importantly, the presence of better synchronization codes over standardized GPS and Galileo codes corroborates the benefits and the need for short synchronization code design.Peer Reviewe

    Factors associated with unexplained sudden deaths among adults aged 18-45 years in India – A multicentric matched case–control study

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    Background & objectives: In view of anecdotal reports of sudden unexplained deaths in India's apparently healthy young adults, linking to coronavirus disease 2019 (COVID-19) infection or vaccination, we determined the factors associated with such deaths in individuals aged 18-45 years through a multicentric matched case–control study. Methods: This study was conducted through participation of 47 tertiary care hospitals across India. Cases were apparently healthy individuals aged 18-45 years without any known co-morbidity, who suddenly (<24 h of hospitalization or seen apparently healthy 24 h before death) died of unexplained causes during 1st October 2021-31st March 2023. Four controls were included per case matched for age, gender and neighborhood. We interviewed/perused records to collect data on COVID-19 vaccination/infection and post-COVID-19 conditions, family history of sudden death, smoking, recreational drug use, alcohol frequency and binge drinking and vigorous-intensity physical activity two days before death/interviews. We developed regression models considering COVID-19 vaccination ≤42 days before outcome, any vaccine received anytime and vaccine doses to compute an adjusted matched odds ratio (aOR) with 95 per cent confidence interval (CI). Results: Seven hundred twenty nine cases and 2916 controls were included in the analysis. Receipt of at least one dose of COVID-19 vaccine lowered the odds [aOR (95% CI)] for unexplained sudden death [0.58 (0.37, 0.92)], whereas past COVID-19 hospitalization [3.8 (1.36, 10.61)], family history of sudden death [2.53 (1.52, 4.21)], binge drinking 48 h before death/interview [5.29 (2.57, 10.89)], use of recreational drug/substance [2.92 (1.1, 7.71)] and performing vigorous-intensity physical activity 48 h before death/interview [3.7 (1.36, 10.05)] were positively associated. Two doses lowered the odds of unexplained sudden death [0.51 (0.28, 0.91)], whereas single dose did not. Interpretation & conclusions: COVID-19 vaccination did not increase the risk of unexplained sudden death among young adults in India. Past COVID-19 hospitalization, family history of sudden death and certain lifestyle behaviors increased the likelihood of unexplained sudden death

    Cellular and molecular mechanisms of renal fibrosis

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