Poly[[piperazine-1,4-dium [diaqua­tetra­kis­(μ-sulfanediyldiacetato)­dicerate(III)]] trihydrate]

The title compound, (C4H12N2)[Ce2(C4H4O4S)4(H2O)2]·3H2O, features a polymeric anion with a centrosymmetric Ce2O2 core and a Ce⋯Ce distance of 4.3625 (4) Å. The anions form ribbons {[Ce2(C4H4O4S)4(H2O)2]2−}n extending along [100]. The doubly protonated piperazinium cations reside on centers of inversion and link the polymeric ribbons via N—H⋯O hydrogen bonding. Each CeIII cation is ten-coordinated by an O2S donor set from two tridentate sulfanediyldiacetate (tda) ligands, one water mol­ecule and three other tda O donors from adjacent {Ce(tda)2(H2O)} units in a distorted bicapped cubic environment. Additional O—H⋯O hydrogen bonding involving the coordinated and solvent water mol­ecules is also present. H atoms of the crystal water molecules could not be located and were not included in the refinement

Poly[[piperazine-1,4-dium [diaqua-tetra-kis-(μ-sulfanediyldiacetato)-dicerate(III)]] trihydrate].

The title compound, (C(4)H(12)N(2))[Ce(2)(C(4)H(4)O(4)S)(4)(H(2)O)(2)]·3H(2)O, features a polymeric anion with a centrosymmetric Ce(2)O(2) core and a Ce⋯Ce distance of 4.3625 (4) Å. The anions form ribbons {[Ce(2)(C(4)H(4)O(4)S)(4)(H(2)O)(2)](2-)}(n) extending along [100]. The doubly protonated piperazinium cations reside on centers of inversion and link the polymeric ribbons via N-H⋯O hydrogen bonding. Each Ce(III) cation is ten-coordinated by an O(2)S donor set from two tridentate sulfanediyldiacetate (tda) ligands, one water mol-ecule and three other tda O donors from adjacent {Ce(tda)(2)(H(2)O)} units in a distorted bicapped cubic environment. Additional O-H⋯O hydrogen bonding involving the coordinated and solvent water mol-ecules is also present. H atoms of the crystal water molecules could not be located and were not included in the refinement

The relationship between dietary micronutrients and endometriosis: A case-control study

Abstract Background: Fewer studies were on micronutrient intake in women with endometriosis, and the etiology of endometriosis remains unclear between dietary micronutrients and the risk of endometriosis. Objective: This study aimed to investigate the relationship between dietary micronutrients and the risk of endometriosis. Materials and Methods: This case-control study was conducted on 156 women (18-45 yr) with and without endometriosis in the gynecology clinic of Arash hospital between May 2017 and May 2018 in Tehran, Iran. According to the laparoscopic findings, the participants were divided into 2 groups (n = 78/each), women with pelvic endometriosis as the case group and women without endometriosis pelvic as the control group. Dietary data were collected using a validated 168-item semiquantitative food frequency questionnaire with the standard serving. A logistic regression model was used to determine the association between micronutrients and the risk of endometriosis. Results: Data analysis showed a significant relationship between micronutrients such as: potassium (OR: 0.74; CI: 0.56-0.99; p = 0.01), calcium (OR: 0.70; CI: 0.52-0.94; p = 0.003), and also among the vitamin C (OR: 0.70; CI: 0.52-0.94; p = 0.02), B2 (OR: 0.73; CI: 0.55-0.98; p = 0.01), and B12 (OR: 0.71; CI: 0.53-0.95; p = 0.02) with endometriosis, so those who used fewer micronutrients were at higher risk of endometriosis. Conclusion: The findings showed that the dietary intakes of calcium, potassium, vitamins B12, B2, B6, and C are inversely related to the risk of endometriosis

Diagnostic Salivary Biomarkers in Traumatic Brain Injury: Narrative Review

Traumatic brain injury (TBI) is a common cause of disability and mortality worldwide. TBI is an acquired brain injury that may be open (penetrating) or closed (non-penetrating) and is be categorized as mild, moderate, or severe, depending on the clinical presentation. Accurate diagnosis at the earliest stages can significantly affect patient discomfort, prognosis, therapeutic intervention, survival rates and recurrence. Whereas traditional CT and MRI techniques for diagnosis are dominant in clinical situations, a promising direction for clinical diagnosis is the use of fluid biomarkers like blood, CSF, urine, and saliva. Fluid biomarkers that may track these injuries and inflammatory processes have been explored for their potential to provide objective measures in TBI assessment. At present, there are limited clinical guidelines available regarding the use of fluid biomarkers in TBI. In recent years, saliva has received significant attention as a biomarker for TBI in clinical practice due to the non-invasive accessibility, cost-effective collection, and consistent relationship with serum. This review examines the utility of saliva biomarkers such as S100B, noncoding RNAs (ncRNAs), extracellular vesicles (EVs), miRNAs levels, microtubule-associated protein tau, alpha-amylase, cortisol, and oxidative stress in TBI. The study highlights the current state of salivary diagnostics, future aspirations, and their potential as the preferred route of TBI detection. The newly developed techniques for salivary analysis of these molecules may help to improve outcomes for TBI through rapid detection current unavailable with serum samples. Future studies via salivary biomarkers will help establish consistent strategies for early diagnosis of TBI and improve treatment outcomes of TBI patients