4 research outputs found

    A Review of Numerical Simulation Strategies for Hydraulic Fracturing, Natural Fracture Reactivation and Induced Microseismicity Prediction

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    Hydraulic fracturing, natural fracture reactivation and resulting induced microseismicity are interconnected phenomena involved in shale gas exploitation. Due to their multi-physics and their complexity, deep understanding of these phenomena as well as their mutual interaction require the adoption of coupled mechanical and fluid flow approaches. Modeling these systems is a challenging procedure as the involved processes take place on different scales of space and also require adequate multidisciplinary knowledge. An extensive literature review is presented here to provide knowledge on the modeling approaches adopted for these coupled problems. The review is intended as a guide to select effective modeling approaches for problems of different complexit

    Natural-Fracture Reactivation in Shale Gas Reservoir and Resulting Microseismicity

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    A geomechanical and fluid-flow coupled model was developed to simulate natural-fracture network reactivation during hydraulic fracturing treatments in shale gas reservoirs. The fractures were modelled using the continuum approach in a commercial finite-difference code, labeled the "softening ubiquitous joints" model with randomply distributed strength parameters to describe heterogeneity along the fracture plane. The models allow for intersecting fractures to represent realistic scenarios. The permeability values in the fractures are dynamically updated during the simulations together with the reversible tensile opening because of elastic response and irreversible shear opening caused by plastic deformations. The reactivation of the fracture network resulted in hugh permeability along these fracture planes. The developed model can predict microseismic events caused by slip on the fracture planes. The magnitude levels of these microseismic events are comparable with the levels observed in events monitored by use of geophone arrays during hydraulic-fracturing treatments for different shale gas reservoir

    Proceedings of the 1st Liaquat University of Medical & Health Sciences (LUMHS) International Medical Research Conference

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    Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study

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    Background Stratifying risk of postoperative pulmonary complications after major abdominal surgery allows clinicians to modify risk through targeted interventions and enhanced monitoring. In this study, we aimed to identify and validate prognostic models against a new consensus definition of postoperative pulmonary complications. Methods We did a systematic review and international external validation cohort study. The systematic review was done in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched MEDLINE and Embase on March 1, 2020, for articles published in English that reported on risk prediction models for postoperative pulmonary complications following abdominal surgery. External validation of existing models was done within a prospective international cohort study of adult patients (≥18 years) undergoing major abdominal surgery. Data were collected between Jan 1, 2019, and April 30, 2019, in the UK, Ireland, and Australia. Discriminative ability and prognostic accuracy summary statistics were compared between models for the 30-day postoperative pulmonary complication rate as defined by the Standardised Endpoints in Perioperative Medicine Core Outcome Measures in Perioperative and Anaesthetic Care (StEP-COMPAC). Model performance was compared using the area under the receiver operating characteristic curve (AUROCC). Findings In total, we identified 2903 records from our literature search; of which, 2514 (86·6%) unique records were screened, 121 (4·8%) of 2514 full texts were assessed for eligibility, and 29 unique prognostic models were identified. Nine (31·0%) of 29 models had score development reported only, 19 (65·5%) had undergone internal validation, and only four (13·8%) had been externally validated. Data to validate six eligible models were collected in the international external validation cohort study. Data from 11 591 patients were available, with an overall postoperative pulmonary complication rate of 7·8% (n=903). None of the six models showed good discrimination (defined as AUROCC ≥0·70) for identifying postoperative pulmonary complications, with the Assess Respiratory Risk in Surgical Patients in Catalonia score showing the best discrimination (AUROCC 0·700 [95% CI 0·683–0·717]). Interpretation In the pre-COVID-19 pandemic data, variability in the risk of pulmonary complications (StEP-COMPAC definition) following major abdominal surgery was poorly described by existing prognostication tools. To improve surgical safety during the COVID-19 pandemic recovery and beyond, novel risk stratification tools are required. Funding British Journal of Surgery Society
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