5-[(E)-(2,6-Dichloro­benzyl­idene)amino]-2-hy­droxy­benzoic acid

There are two geometrically different mol­ecules in the asymmetric unit of the title compound, C14H9Cl2NO3. The 5-amino-2-hy­droxy­benzoic acid units [r.m.s. deviations of 0.0323 and 0.0414 Å] and 2,6-dichloro­benzaldehyde groups [r.m.s. deviations of 0.0285 and 0.0226 Å] are roughly planar and oriented at dihedral angles of 11.69 (13) and 83.12 (6)° in the two mol­ecules. An intra­molecular O—H⋯O hydrogen bond completes an S(6) ring motif in each mol­ecule. The two mol­ecules form dimers with each other through inter­molecular O—H⋯N and C—H⋯O hydrogen bonds, completing an R 2 2(8) ring motif. The dimers are inter­linked via inter­molecular O—H⋯N and C—H⋯O hydrogen bonds, forming polymeric sheets

2-{[(E)-1,3-Benzodioxol-5-yl]methyl­idene­amino}­benzoic acid

In the title compound, C15H11NO4, the dihedral angle between the aromatic rings is 23.8 (2)° and an intra­molecular O—H⋯N hydrogen bond generates an S(6) ring. In the crystal, C—H⋯O hydrogen bonds link the mol­ecules into a three-dimensional network

Field Application of Trichogramma chilonis (Ishii) for the Management of Sugarcane Borers

Abstract.-These studies were conducted at farmer's fields in Mardan district during the cropping season [2008][2009] to investigate the efficacy and potentiality of inundative and inoculative release methods of Trichogramma chilonis (Ishii) for the management of sugarcane borers. The experiment was laid out in Randomized Complete Block Design. There were three treatments and four replications in each treatment. The data revealed that both inundative and inoculative release methods of T. chilonis were more effective as compared with the control throughout the entire growing season. Inundative release method of T. chilonis was found the most effective technique against Chilo infuscatellus (Snellen) infestation in both sugarcane plant and ratoon crops with minimum mean percent infestation of 3.50 and 6.50 respectively. This was followed by Inoculative release method, where 6.75 and 10.00 mean percent infestation was recorded in sugarcane plant and ratoon crops respectively. Maximum infestation was recorded in control plots with mean percent infestation of 7.87 and 12.75 in sugarcane plant and ratoon crops respectively. The data further revealed that inundative release method of T. chilonis in both sugarcane plant and ratoon crops also effectively controlled Acigona steniellus (Hamp) with minimum borer's infestation by recording 3.25 and 3.37 mean percent infestations in both sugarcane plant and ratoon crops respectively. It was followed by the plots where T. chilonis were released as inoculative release method, where 4.87 and 6.25 mean percent infestation was recorded in sugarcane plant and ratoon crop respectively. Control plots showed maximum A. steniellus infestation in plant crop (7.27%) and ratoon crop (7.65%). The data further showed that no Scirpophaga nivella Fabric infestation was recorded in both sugarcane plant and ratoon crops. Maximum yield of sugarcane was recorded in both plant and ratoon crops of sugarcane in plots treated with inundative release method (101.5t/ha in plant crop and 69.25 t/ha in ratoon crop) followed by inoculative release method (95.84t/ha in plant crop and 63.14t/ha in ratoon crop). The lowest yield of sugarcane was recorded in control (91.14 t/ha and 58.33 t/ha)

Brief review: Applications of nanocomposite in electrochemical sensor and drugs delivery

The recent advancement of nanoparticles (NPs) holds significant potential for treating various ailments. NPs are employed as drug carriers for diseases like cancer because of their small size and increased stability. In addition, they have several desirable properties that make them ideal for treating bone cancer, including high stability, specificity, higher sensitivity, and efficacy. Furthermore, they might be taken into account to permit the precise drug release from the matrix. Drug delivery systems for cancer treatment have progressed to include nanocomposites, metallic NPs, dendrimers, and liposomes. Materials’ mechanical strength, hardness, electrical and thermal conductivity, and electrochemical sensors are significantly improved using nanoparticles (NPs). New sensing devices, drug delivery systems, electrochemical sensors, and biosensors can all benefit considerably from the NPs’ exceptional physical and chemical capabilities. Nanotechnology is discussed in this article from a variety of angles, including its recent applications in the medical sciences for the effective treatment of bone cancers and its potential as a promising option for treating other complex health anomalies via the use of anti-tumour therapy, radiotherapy, the delivery of proteins, antibiotics, and vaccines, and other methods. This also brings to light the role that model simulations can play in diagnosing and treating bone cancer, an area where Nanomedicine has recently been formulated. There has been a recent uptick in using nanotechnology to treat conditions affecting the skeleton. Consequently, it will pave the door for more effective utilization of cutting-edge technology, including electrochemical sensors and biosensors, and improved therapeutic outcomes

Are we doing enough? Evaluation of the Polio Eradication Initiative in a district of Pakistan's Punjab province: a LQAS study

<p>Abstract</p> <p>Background</p> <p>The success of the Global Polio Eradication Initiative was remarkable, but four countries - Afghanistan, Pakistan, India and Nigeria - never interrupted polio transmission. Pakistan reportedly achieved all milestones except interrupting virus transmission. The aim of the study was to establish valid and reliable estimate for: routine oral polio vaccine (OPV) coverage, logistics management and the quality of monitoring systems in health facilities, NIDs OPV coverage, the quality of NIDs service delivery in static centers and mobile teams, and to ultimately provide scientific evidence for tailoring future interventions.</p> <p>Methods</p> <p>A cross-sectional study using lot quality assessment sampling was conducted in the District Nankana Sahib of Pakistan's Punjab province. Twenty primary health centers and their catchment areas were selected randomly as <it>'lots'</it>. The study involved the evaluation of 1080 children aged 12-23 months for routine OPV coverage, 20 health centers for logistics management and quality of monitoring systems, 420 households for NIDs OPV coverage, 20 static centers and 20 mobile teams for quality of NIDs service delivery. Study instruments were designed according to WHO guidelines.</p> <p>Results</p> <p>Five out of twenty lots were rejected for unacceptably low routine immunization coverage. The validity of coverage was questionable to extent that all lots were rejected. Among the 54.1% who were able to present immunization cards, only 74.0% had valid immunization. Routine coverage was significantly associated with card availability and socioeconomic factors. The main reasons for routine immunization failure were absence of a vaccinator and unawareness of need for immunization. Health workers (96.9%) were a major source of information. All of the 20 lots were rejected for poor compliance in logistics management and quality of monitoring systems. Mean compliance score and compliance percentage for logistics management were 5.4 ± 2.0 (scale 0-9) and 59.4% while those for quality of monitoring systems were 3.3 ± 1.2 (scale 0-6) and 54.2%. The 15 out of 20 lots were rejected for unacceptably low NIDs coverage by finger-mark. All of the 20 lots were rejected for poor NIDs service delivery (mean compliance score = 11.7 ± 2.1 [scale 0-16]; compliance percentage = 72.8%).</p> <p>Conclusion</p> <p>Low coverage, both routine and during NIDs, and poor quality of logistics management, monitoring systems and NIDs service delivery were highlighted as major constraints in polio eradication and these should be considered in prioritizing future strategies.</p

Why Competitive Intelligence Fail: Interrogating the Correlates of CI Failure in the Nigerian Brewery Industry

Globally, as businesses grapple with uncertainties and challenges of growth and expansion, competitive intelligence failure has remained an obvious reality. This work therefore attempts to evaluate the intervening variables underlying the menace of competitive intelligence failure in the business world. Specifically, the study identifies the factors responsible for CI failures in the brewery industry in Nigeria. The identified factors include; lack of planning and management skills by managers and top company executives, faulty business decision making process and implementation by management and lack of coordinated organisational culture and political climate in the brewery industry in the country. In reaching these analytical premises, the study adopted a quantitative evaluation of some breweries in Nigeria to determine the pattern and trends of the competitive intelligence correlates and offered corresponding recommendations that will help to mitigate the menace of competitive failure in Nigeria. Key Words: Competitive Intelligence, Correlates, Failure, Nigeria, Brewery Industr

Crystal structure of (E)-2-[(4-hydroxybenzylidene)azaniumyl]benzoate

The title Schiff base, C14H11NO3, crystallizes as a zwitterion (i.e. proton transfer from the carboxylic acid group to the imine N atom). The dihedral angle between the aromatic rings is 19.59 (6)° and an intramolecular N—H...O hydrogen bond closes an S(6) ring. In the crystal, inversion dimers linked by pairs of O—H...O hydrogen bonds generate R24(24) loops. The dimers are linked by C—H...O interactions, generating (211) sheets