987 research outputs found
The Physics of Compressive Sensing and the Gradient-Based Recovery Algorithms
The physics of compressive sensing (CS) and the gradient-based recovery
algorithms are presented. First, the different forms for CS are summarized.
Second, the physical meanings of coherence and measurement are given. Third,
the gradient-based recovery algorithms and their geometry explanations are
provided. Finally, we conclude the report and give some suggestion for future
work.Comment: 7 pages, 11 Figures. It is a research report which has not been
published in any Journal or Conferenc
Casimir Force for Arbitrary Objects Using the Argument Principle and Boundary Element Methods
Recent progress in the simulation of Casimir forces between various objects
has allowed traditional computational electromagnetic solvers to be used to
find Casimir forces in arbitrary three-dimensional objects. The underlying
theory to these approaches requires knowledge and manipulation of quantum field
theory and statistical physics. We present a calculation of the Casimir force
using the method of moments via the argument principle. This simplified
derivation allows greater freedom in the moment matrix where the argument
principle can be used to calculate Casimir forces for arbitrary geometries and
materials with the use of various computational electromagnetic techniques.Comment: 6 pages, 2 figure
New definition of potential spicity by the least square method
Author Posting. © American Geophysical Union, 2018. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research: Oceans 123 (2018): 7351-7365, doi:10.1029/2018JC014306.A differentiable function whose contours are orthogonal to potential density (σ) contours does not exist. However, such a function, called potential spicity (π), can be defined in the least square sense; these two functions form a practically orthogonal coordinate system in potential temperature‐salinity (θ‐S) space. Thus, in addition to the classical potential temperature‐salinity (θ‐S) diagram, seawater properties can be studied in the potential density‐potential spicity (σ − π) diagram.Guangzhou Science and Technology Program key projects. Grant Number: 201804020056
National Natural Science Foundation of China. Grant Numbers: 41476167, 91752108
National Natural Science Foundation of Guangdong Province, China Grant Number: 2016A030311042;
Strategic Priority Research Program of the Chinese Academy of Sciences Grant Number: XDA11030302;
Guangzhou Science and Technology Program;
NSF of Guangdong Province, China2019-04-1
Identifying risk factors for cesarean scar pregnancy: a retrospective study of 79 cases
Objectives: To explore the possible risk factors for cesarean scar pregnancy (CSP), the incidence of which is increasing rapidly in China. Material and methods: 79 patients with CSP and 69 non-CSP expectant mothers with at least 1 previous cesarean section were employed in the study. The obstetric histories of the participants were collected and analyzed using Chi square test. Results: We found that 77.2% CSP patients had ≥ 3 pregnancies and only 36.2% women had ≥ 3 pregnacies in non-CSP group. During the previous cesarean delivery, 21.5% of CSP patients had entered the first stage of labor, which was 43.5% in non-CSP group (P < 0.05). Cephalopelvic disproportion occurred in 51.9% of CSP patients, which was significantly higher than that (23.2%) in non-CSP group (P < 0.01). 11.4% of CSP patients had undergone cesarean section due to breech and shoulder presentation in the past, which was only 1.4% in non-CSP group. However, no significance was noted (P > 0.05). We did not find significant differences between the CSP and non-CSP patients in maternal age, multiple cesarean sections, gestational age, emergency or elective caesarean section. Conclusions: Multiple pregnancies, absence of the first stage of labor, and cephalopelvic disproportion might be the risk factors for the occurrence of CSP.
URLLC packet management for packetized predictive control
Packetized predictive control (PPC) is an effective
solution to ensure the robustness of the control
system over unreliable wireless links. However, conventional
wireless transmission methods in PPC suffer from either
high wireless resource consumption or poor performance of
real-time control due to the separately design of the two
parts. To deal with the issue, we propose a communicationcontrol
co-design approach to achieve good trade-off between
real-time control performance and communication
energy efficiency. Our results demonstrate the advantages
of the communication-control co-design
A network pharmacology-based study on the anti-hepatoma effect of Radix Salviae Miltiorrhizae
This work is licensed under a Creative Commons Attribution 4.0 International License.Background
Radix Salviae Miltiorrhizae (RSM), a well-known traditional Chinese medicine, has been shown to inhibit tumorigenesis in various human cancers. However, the anticancer effects of RSM on human hepatocellular carcinoma (HCC) and the underlying mechanisms of action remain to be fully elucidated.
Methods
In this study, we aimed to elucidate the underlying molecular mechanisms of RSM in the treatment of HCC using a network pharmacology approach. In vivo and in vitro experiments were also performed to validate the therapeutic effects of RSM on HCC.
Results
In total, 62 active compounds from RSM and 72 HCC-related targets were identified through network pharmacological analysis. RSM was found to play a critical role in HCC via multiple targets and pathways, especially the EGFR and PI3K/AKT signaling pathways. In addition, RSM was found to suppress HCC cell proliferation, and impair cancer cell migration and invasion in vitro. Flow cytometry analysis revealed that RSM induced cell cycle G2/M arrest and apoptosis, and western blot analysis showed that RSM up-regulated the expression of BAX and down-regulated the expression of Bcl-2 in MHCC97-H and HepG2 cells. Furthermore, RSM administration down-regulated the expression of EGFR, PI3K, and p-AKT proteins, whereas the total AKT level was not altered. Finally, the results of our in vivo experiments confirmed the therapeutic effects of RSM on HCC in nude mice.
Conclusions
We provide an integrative network pharmacology approach, in combination with in vitro and in vivo experiments, to illustrate the underlying therapeutic mechanisms of RSM action on HCC
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