Abdominal fat segmentation using T1- and T2*- corrected images and characterization by proton spectroscopy: preliminary study

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Comparison of 3D spoiled-gradient multiple echo with STEAM for proton density fat fraction and fatty acid composition estimation

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Effect of polyphenols during a high-fat diet enhanced with chemical shift-encoded MRI

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Effect of polyphenols during a high-fat diet enhanced with chemical shift-encoded MRI

International audienceFull abstract available online at:http://indexsmart.mirasmart.com/ISMRM2018/PDFfiles/4725.htmlRésumé disponible en ligne : http://indexsmart.mirasmart.com/ISMRM2018/PDFfiles/4725.htm

Comparison of 3D spoiled-gradient multiple echo with STEAM for proton density fat fraction and fatty acid composition estimation

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Etude de modèles paramétriques pour l'estimation de la composition lipidique en spectroscopie de résonance magnétique : comparaison théorique des fonctions modèles et application in vivo

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Etude de modèles paramétriques pour l'estimation de la composition lipidique en spectroscopie de résonance magnétique : comparaison théorique des fonctions modèles et application in vivo

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Effect of the phase variation induced by eddy currents on localized spectroscopy fatty acid composition quantification and its correction

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Effect of the phase variation induced by eddy currents on localized spectroscopy fatty acid composition quantification and its correction

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Plasma acyl-ghrelin increases after meal initiation: a new insight

BACKGROUND/OBJECTIVES: Plasma ghrelin secretion over time in humans is characterized by pre-prandial increases and by post-prandial decreases all day long. However, some authors who measured ghrelin concentrations around meals showed a rise in plasma ghrelin concentration after meal initiation followed by the typical post-prandial decrease. In order to confirm this observation that has never been discussed, we described ghrelin profiles around four eating episodes in the morning in adult men.SUBJECTS/METHODS: Twenty normal-weight and 17 obese men were instructed to eat four fixed meals (706 kJ) 10 min long at 0800 h, 0900 h, 1000 h and 1100 h. Using frequent blood sampling, we determined plasma acyl-ghrelin concentrations around those eating episodes. Glucose, insulin and GLP-1 concentrations were also measured.RESULTS: The meals consumption induced a significant increase in plasma acyl-ghrelin concentrations 10 min after meal initiation (P<0.0001): +20.9 +/- 5.8 and +10.7 +/- 3.3 pg/ml in normal-weight and obese subjects for the first meal; +10.4 +/- 3.0 and +5.5 +/- 3.9 pg/ml in normal-weight and obese subjects for the second meal; +12.4 +/- 3.6 and +4.2 +/- 2.1 pg/ml in normal-weight and obese subjects for the third meal; and +4.4 +/- 4.1 and +3.3 +/- 2.61 pg/ml in normal-weight and obese subjects for the fourth meal.CONCLUSIONS: This study is the first to describe and discuss the post-meal initiation ghrelin increase. This finding is consistent in normal-weight and obese individuals