Mango anthracnose disease: the current situation and direction for future research

Mango anthracnose disease (MAD) is a destructive disease of mangoes, with estimated yield losses of up to 100% in unmanaged plantations. Several strains that constitute Colletotrichum complexes are implicated in MAD worldwide. All mangoes grown for commercial purposes are susceptible, and a resistant cultivar for all strains is not presently available on the market. The infection can widely spread before being detected since the disease is invincible until after a protracted latent period. The detection of multiple strains of the pathogen in Mexico, Brazil, and China has prompted a significant increase in research on the disease. Synthetic pesticide application is the primary management technique used to manage the disease. However, newly observed declines in anthracnose susceptibility to many fungicides highlight the need for more environmentally friendly approaches. Recent progress in understanding the host range, molecular and phenotypic characterization, and susceptibility of the disease in several mango cultivars is discussed in this review. It provides updates on the mode of transmission, infection biology and contemporary management strategies. We suggest an integrated and ecologically sound approach to managing MAD

Community vulnerability assessment index for flood prone savannah agro-ecological zone: A case study of Wa West District, Ghana

The savannah regions of Northern Ghana are characterized by smallholder farming systems and high levels of poverty. Over the past two decades, communities in the regions have become more prone to climate and human-induced disasters in the form of annual floods and droughts. This study evaluates the degree and magnitude of vulnerability in four communities subjected to similar climate change induced flood events and propose intervention options. The study employs rural participatory research approaches in developing four vulnerability categories namely socio-economic, ecological, engineering and political; which were used to develop indicators that aided the calculation of total community vulnerability index for each community. The findings indicate that the state of a community's vulnerability to flood is a composite effect of the four vulnerability index categories which may act independently or concurrently to produce the net effect. Based on a synthesis of total vulnerability obtained in each community, Baleufili was found to be the least vulnerable to flood due to its high scores in engineering, socio-economic and political vulnerability indicators. Baleufili and Bankpama were the most ecologically vulnerable communities. The selection of vulnerability index categories and associated indicators were grounded in specific local peculiarities that evolved out of engagement with community stakeholders and expert knowledge of the socioecological landscape. Thus, the Total Community Vulnerability Assessment Framework (TCVAF) provides an effective decision support for identifying communities’ vulnerability status and help to design both short and long term interventions options that are community specific as a way of enhancing their coping and adaptive capacity to disasters

The Global Impact of COVID-19: Historical Development, Molecular Characterization, Drug Discovery and Future Directions

In December 2019, an outbreak of a respiratory disease called the coronavirus disease 2019 (COVID-19) caused by a new coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in Wuhan, China. The SARS-CoV-2, an encapsulated positive-stranded RNA virus, spread worldwide with disastrous consequences for people’s health, economies, and quality of life. The disease has had far-reaching impacts on society, including economic disruption, school closures, and increased stress and anxiety. It has also highlighted disparities in healthcare access and outcomes, with marginalized communities disproportionately affected by the SARS-CoV-2. The symptoms of COVID-19 range from mild to severe. There is presently no effective cure. Nevertheless, significant progress has been made in developing COVID-19 vaccine for different therapeutic targets. For instance, scientists developed multifold vaccine candidates shortly after the COVID-19 outbreak after Pfizer and AstraZeneca discovered the initial COVID-19 vaccines. These vaccines reduce disease spread, severity, and mortality. The addition of rapid diagnostics to microscopy for COVID-19 diagnosis has proven crucial. Our review provides a thorough overview of the historical development of COVID-19 and molecular and biochemical characterization of the SARS-CoV-2. We highlight the potential contributions from insect and plant sources as anti-SARS-CoV-2 and present directions for future research